SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vnu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 LEU D 604
PRO D 605
LEU D 608
 None
 0.51A 1hrkA-2vnuD:
undetectable		 1hrkA-2vnuD:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWF_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		5 / 9 LEU D 733
VAL D 566
VAL D 626
GLY D 567
LEU D 684
 None
 1.30A 1lwfA-2vnuD:
undetectable		 1lwfA-2vnuD:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		4 / 8 GLY D 271
GLY D 267
GLY D 266
LEU D 268
 None
 0.56A 1qzzA-2vnuD:
undetectable		 1qzzA-2vnuD:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_2
(PROTEASE)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		5 / 11 LEU D 407
VAL D 434
ILE D 453
VAL D 422
VAL D 424
 None
 0.90A 2nnpB-2vnuD:
undetectable		 2nnpB-2vnuD:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 LEU D 431
PRO D 432
LEU D 426
 None
 0.56A 2po7B-2vnuD:
undetectable		 2po7B-2vnuD:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 LEU D 604
PRO D 605
LEU D 608
 None
 0.49A 2qd5B-2vnuD:
undetectable		 2qd5B-2vnuD:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 LEU D 790
ASN D 695
ARG D 806
 None
 0.98A 2qhfA-2vnuD:
undetectable		 2qhfA-2vnuD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 PRO D 457
LEU D 464
ARG D 437
 None
 0.92A 3aqiA-2vnuD:
undetectable		 3aqiA-2vnuD:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_2
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		4 / 4 VAL D 568
ARG D 688
ILE D 636
THR D 843
 None
None
None
A  B  -2 ( 3.2A)
 1.28A 3cl9A-2vnuD:
undetectable		 3cl9A-2vnuD:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_2
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		4 / 4 VAL D 577
ARG D 590
ILE D 884
THR D 581
 None
 1.33A 3cl9A-2vnuD:
undetectable		 3cl9A-2vnuD:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		4 / 5 VAL D 499
THR D 592
GLY D 591
LYS D 887
 None
 1.08A 3elzB-2vnuD:
2.4		 3elzB-2vnuD:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		5 / 12 LEU D 780
LEU D 696
LEU D 694
GLY D 833
HIS D 755
 None
A  B  -5 ( 4.2A)
None
A  B  -5 ( 3.4A)
A  B  -5 ( 3.5A)
 0.98A 3g1uA-2vnuD:
undetectable		 3g1uA-2vnuD:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		5 / 12 LEU D 780
LEU D 696
LEU D 694
GLY D 833
HIS D 755
 None
A  B  -5 ( 4.2A)
None
A  B  -5 ( 3.4A)
A  B  -5 ( 3.5A)
 1.00A 3g1uB-2vnuD:
undetectable		 3g1uB-2vnuD:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		5 / 12 LEU D 780
LEU D 696
LEU D 694
GLY D 833
HIS D 755
 None
A  B  -5 ( 4.2A)
None
A  B  -5 ( 3.4A)
A  B  -5 ( 3.5A)
 0.98A 3g1uD-2vnuD:
undetectable		 3g1uD-2vnuD:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		5 / 12 LEU D 780
LEU D 696
LEU D 694
GLY D 833
HIS D 755
 None
A  B  -5 ( 4.2A)
None
A  B  -5 ( 3.4A)
A  B  -5 ( 3.5A)
 0.95A 3glqA-2vnuD:
undetectable		 3glqA-2vnuD:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		5 / 12 LEU D 780
LEU D 696
LEU D 694
GLY D 833
HIS D 755
 None
A  B  -5 ( 4.2A)
None
A  B  -5 ( 3.4A)
A  B  -5 ( 3.5A)
 0.98A 3glqB-2vnuD:
undetectable		 3glqB-2vnuD:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 GLY D 833
PRO D 758
LEU D 786
 A  B  -5 ( 3.4A)
None
None
 0.56A 3hcpB-2vnuD:
undetectable		 3hcpB-2vnuD:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 LEU D 431
PRO D 432
LEU D 426
 None
 0.34A 3hcrA-2vnuD:
undetectable		 3hcrA-2vnuD:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 LEU D 604
PRO D 605
LEU D 608
 None
 0.48A 3hcrA-2vnuD:
undetectable		 3hcrA-2vnuD:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 ASN D 551
ASP D 549
ARG D 896
 A  B  -1 ( 3.9A)
A  B  -1 ( 2.3A)
A  B  -6 ( 3.9A)
 0.91A 3k13C-2vnuD:
undetectable		 3k13C-2vnuD:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 PHE D 829
TYR D 820
LEU D 834
 None
None
A  B  -4 ( 4.4A)
 0.72A 3keeB-2vnuD:
undetectable		 3keeB-2vnuD:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		5 / 12 LEU D 780
LEU D 696
LEU D 694
GLY D 833
HIS D 755
 None
A  B  -5 ( 4.2A)
None
A  B  -5 ( 3.4A)
A  B  -5 ( 3.5A)
 1.03A 3n58A-2vnuD:
undetectable		 3n58A-2vnuD:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		4 / 5 HIS D 555
ILE D 539
HIS D 569
LEU D 534
 None
 1.46A 3qpkA-2vnuD:
undetectable		 3qpkA-2vnuD:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_A_SALA301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		4 / 8 ARG D 971
VAL D 973
VAL D 981
ILE D 939
 None
 1.06A 3remA-2vnuD:
undetectable		 3remA-2vnuD:
8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_B_SALB301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		4 / 8 ARG D 971
VAL D 973
VAL D 981
ILE D 939
 None
 1.05A 3remB-2vnuD:
undetectable		 3remB-2vnuD:
8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 PHE D 829
TYR D 820
LEU D 834
 None
None
A  B  -4 ( 4.4A)
 0.65A 3sueB-2vnuD:
undetectable		 3sueB-2vnuD:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		4 / 4 LEU D 307
GLY D 303
LEU D 286
GLU D 287
 None
 1.04A 3tgvB-2vnuD:
undetectable		 3tgvB-2vnuD:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 LYS D 687
ARG D 740
LEU D 733
 None
 1.26A 3v4tE-2vnuD:
undetectable		 3v4tE-2vnuD:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 LEU D 604
PRO D 605
LEU D 608
 None
 0.47A 3w1wB-2vnuD:
undetectable		 3w1wB-2vnuD:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		4 / 6 GLU D 957
ARG D 773
ASP D 972
ASP D 977
 None
 1.28A 4kcnA-2vnuD:
undetectable		 4kcnA-2vnuD:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		4 / 6 GLU D 957
ARG D 773
ASP D 972
ASP D 977
 None
 1.23A 4kcnB-2vnuD:
undetectable		 4kcnB-2vnuD:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA609_0
(SERUM ALBUMIN)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		4 / 4 ALA D 512
HIS D 575
PHE D 622
LEU D 612
 None
 1.45A 4luhA-2vnuD:
0.0		 4luhA-2vnuD:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		5 / 12 PHE D 801
ARG D 811
SER D 809
MET D 769
LEU D 790
 None
A  B  -6 ( 4.7A)
None
None
None
 1.40A 4o8fA-2vnuD:
0.0		 4o8fA-2vnuD:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		4 / 6 ILE D 884
GLY D 587
VAL D 577
HIS D 871
 None
 1.07A 4oltA-2vnuD:
undetectable		 4oltA-2vnuD:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		5 / 12 ILE D 449
GLY D 405
PHE D 467
VAL D 424
ILE D 436
 None
 0.89A 4rvdA-2vnuD:
undetectable		 4rvdA-2vnuD:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		5 / 12 ILE D 449
GLY D 405
PHE D 467
VAL D 424
ILE D 436
 None
 0.91A 4rvgA-2vnuD:
undetectable		 4rvgA-2vnuD:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		4 / 7 ILE D 425
ILE D 449
ILE D 436
LEU D 444
 None
 0.74A 5fukA-2vnuD:
undetectable
5fukB-2vnuD:
undetectable		 5fukA-2vnuD:
16.84
5fukB-2vnuD:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.50A 5qgjA-2vnuD:
undetectable		 5qgjA-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.51A 5qglA-2vnuD:
undetectable		 5qglA-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.54A 5qgmA-2vnuD:
undetectable		 5qgmA-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.46A 5qgnA-2vnuD:
undetectable		 5qgnA-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.57A 5qguA-2vnuD:
undetectable		 5qguA-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.55A 5qgvA-2vnuD:
undetectable		 5qgvA-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.58A 5qgwA-2vnuD:
undetectable		 5qgwA-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.55A 5qgxA-2vnuD:
undetectable		 5qgxA-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.56A 5qgyA-2vnuD:
undetectable		 5qgyA-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.56A 5qh1A-2vnuD:
undetectable		 5qh1A-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.56A 5qh3A-2vnuD:
undetectable		 5qh3A-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.54A 5qh4A-2vnuD:
undetectable		 5qh4A-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.50A 5qh5A-2vnuD:
undetectable		 5qh5A-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.55A 5qh6A-2vnuD:
undetectable		 5qh6A-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.53A 5qh7A-2vnuD:
undetectable		 5qh7A-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.56A 5qh9A-2vnuD:
undetectable		 5qh9A-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.56A 5qhcA-2vnuD:
undetectable		 5qhcA-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.58A 5qheA-2vnuD:
undetectable		 5qheA-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.55A 5qhfA-2vnuD:
undetectable		 5qhfA-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.50A 5qhgA-2vnuD:
undetectable		 5qhgA-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 VAL D 392
VAL D 318
GLN D 275
 None
 0.55A 5qhhA-2vnuD:
undetectable		 5qhhA-2vnuD:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 TYR D 820
ASP D 873
ASP D 878
 None
 0.68A 5x6yA-2vnuD:
undetectable		 5x6yA-2vnuD:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44
(Saccharomyces
cerevisiae) 		3 / 3 LEU D 334
SER D 336
PHE D 339
 None
 0.65A 6fgcA-2vnuD:
undetectable		 6fgcA-2vnuD:
20.93