SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vo9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OKB_A_198A1002_2 (ANDROGEN RECEPTOR)	2vo9	L-ALANYL-D-GLUTAMATE PEPTIDASE (Listeria phage A500)	4 / 6	LEU A 16 MET A 114 LEU A 88 VAL A 98	None	0.79A	4okbA-2vo9A: undetectable	4okbA-2vo9A: 21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PFJ_B_ADNB502_1 (ADENOSYLHOMOCYSTEINA SE)	2vo9	L-ALANYL-D-GLUTAMATE PEPTIDASE (Listeria phage A500)	5 / 12	THR A 25 GLU A 135 LEU A 88 GLY A 48 HIS A 80	None None None None ZN A 501 ( 3.2A)	1.26A	4pfjB-2vo9A: undetectable	4pfjB-2vo9A: 16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5F8Y_B_X6XB201_1 (GALNAC/GAL-SPECIFIC LECTIN)	2vo9	L-ALANYL-D-GLUTAMATE PEPTIDASE (Listeria phage A500)	5 / 8	GLY A 123 GLY A 122 VAL A 111 ASP A 87 HIS A 133	None None None ZN A 501 (-2.2A) ZN A 501 (-3.1A)	1.37A	5f8yB-2vo9A: undetectable	5f8yB-2vo9A: 21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HIE_C_P06C801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	2vo9	L-ALANYL-D-GLUTAMATE PEPTIDASE (Listeria phage A500)	4 / 7	ILE A 41 ILE A 9 CYH A 89 ASN A 93	None	0.97A	5hieC-2vo9A: undetectable	5hieC-2vo9A: 21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6APH_A_ADNA501_1 (ADENOSYLHOMOCYSTEINA SE)	2vo9	L-ALANYL-D-GLUTAMATE PEPTIDASE (Listeria phage A500)	5 / 12	THR A 25 GLU A 135 LEU A 88 GLY A 48 HIS A 80	None None None None ZN A 501 ( 3.2A)	1.26A	6aphA-2vo9A: undetectable	6aphA-2vo9A: 18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F3N_A_ADNA505_1 (-)	2vo9	L-ALANYL-D-GLUTAMATE PEPTIDASE (Listeria phage A500)	5 / 12	THR A 25 GLU A 135 LEU A 88 GLY A 48 HIS A 80	None None None None ZN A 501 ( 3.2A)	1.25A	6f3nA-2vo9A: undetectable	6f3nA-2vo9A: 19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F3N_D_ADND506_1 (-)	2vo9	L-ALANYL-D-GLUTAMATE PEPTIDASE (Listeria phage A500)	5 / 12	THR A 25 GLU A 135 LEU A 88 GLY A 48 HIS A 80	None None None None ZN A 501 ( 3.2A)	1.25A	6f3nD-2vo9A: undetectable	6f3nD-2vo9A: 19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GBN_B_ADNB501_1 (-)	2vo9	L-ALANYL-D-GLUTAMATE PEPTIDASE (Listeria phage A500)	5 / 12	THR A 25 GLU A 135 LEU A 88 GLY A 48 HIS A 80	None None None None ZN A 501 ( 3.2A)	1.41A	6gbnB-2vo9A: undetectable	6gbnB-2vo9A: 18.55

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4OKB_A_198A1002_2","ANDROGEN RECEPTOR","2vo9","L-ALANYL-D-GLUTAMATE PEPTIDASE","Listeria phage A500",4,"LEU A  16;MET A 114;LEU A  88;VAL A  98","None","0.79A","4okbA-2vo9A:undetectable","4okbA-2vo9A:21.63"],["4PFJ_B_ADNB502_1","ADENOSYLHOMOCYSTEINASE","2vo9","L-ALANYL-D-GLUTAMATE PEPTIDASE","Listeria phage A500",5,"THR A  25;GLU A 135;LEU A  88;GLY A  48;HIS A  80","None;None;None;None; ZN A 501 ( 3.2A)","1.26A","4pfjB-2vo9A:undetectable","4pfjB-2vo9A:16.86"],["5F8Y_B_X6XB201_1","GALNAC\/GAL-SPECIFIC LECTIN","2vo9","L-ALANYL-D-GLUTAMATE PEPTIDASE","Listeria phage A500",5,"GLY A 123;GLY A 122;VAL A 111;ASP A  87;HIS A 133","None;None;None; ZN A 501 (-2.2A); ZN A 501 (-3.1A)","1.37A","5f8yB-2vo9A:undetectable","5f8yB-2vo9A:21.47"],["5HIE_C_P06C801_2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","2vo9","L-ALANYL-D-GLUTAMATE PEPTIDASE","Listeria phage A500",4,"ILE A  41;ILE A   9;CYH A  89;ASN A  93","None","0.97A","5hieC-2vo9A:undetectable","5hieC-2vo9A:21.36"],["6APH_A_ADNA501_1","ADENOSYLHOMOCYSTEINASE","2vo9","L-ALANYL-D-GLUTAMATE PEPTIDASE","Listeria phage A500",5,"THR A  25;GLU A 135;LEU A  88;GLY A  48;HIS A  80","None;None;None;None; ZN A 501 ( 3.2A)","1.26A","6aphA-2vo9A:undetectable","6aphA-2vo9A:18.60"],["6F3N_A_ADNA505_1","-","2vo9","L-ALANYL-D-GLUTAMATE PEPTIDASE","Listeria phage A500",5,"THR A  25;GLU A 135;LEU A  88;GLY A  48;HIS A  80","None;None;None;None; ZN A 501 ( 3.2A)","1.25A","6f3nA-2vo9A:undetectable","6f3nA-2vo9A:19.02"],["6F3N_D_ADND506_1","-","2vo9","L-ALANYL-D-GLUTAMATE PEPTIDASE","Listeria phage A500",5,"THR A  25;GLU A 135;LEU A  88;GLY A  48;HIS A  80","None;None;None;None; ZN A 501 ( 3.2A)","1.25A","6f3nD-2vo9A:undetectable","6f3nD-2vo9A:19.02"],["6GBN_B_ADNB501_1","-","2vo9","L-ALANYL-D-GLUTAMATE PEPTIDASE","Listeria phage A500",5,"THR A  25;GLU A 135;LEU A  88;GLY A  48;HIS A  80","None;None;None;None; ZN A 501 ( 3.2A)","1.41A","6gbnB-2vo9A:undetectable","6gbnB-2vo9A:18.55"]]