SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2voa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 2voa EXODEOXYRIBONUCLEASE
III
(Archaeoglobus
fulgidus) 		4 / 9 ILE A   4
ALA A  94
VAL A 101
CYH A 144
 None
 0.79A 2vufB-2voaA:
undetectable		 2vufB-2voaA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 2voa EXODEOXYRIBONUCLEASE
III
(Archaeoglobus
fulgidus) 		4 / 6 ASP A 202
ASP A 218
HIS A 248
ASP A 146
 None
 1.09A 3c0zC-2voaA:
undetectable		 3c0zC-2voaA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 2voa EXODEOXYRIBONUCLEASE
III
(Archaeoglobus
fulgidus) 		3 / 3 LEU A   2
GLU A  72
ILE A  96
 None
 0.47A 3czhA-2voaA:
undetectable		 3czhA-2voaA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 2voa EXODEOXYRIBONUCLEASE
III
(Archaeoglobus
fulgidus) 		4 / 5 LYS A 120
GLN A 122
LEU A 124
GLU A 125
 OCS  A 167 ( 3.0A)
None
None
None
 0.85A 3h5gA-2voaA:
undetectable
3h5gB-2voaA:
undetectable		 3h5gA-2voaA:
9.39
3h5gB-2voaA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 2voa EXODEOXYRIBONUCLEASE
III
(Archaeoglobus
fulgidus) 		3 / 3 TYR A 203
ARG A  15
SER A 246
 None
 1.01A 4lf7I-2voaA:
undetectable
4lf7J-2voaA:
undetectable		 4lf7I-2voaA:
20.88
4lf7J-2voaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 2voa EXODEOXYRIBONUCLEASE
III
(Archaeoglobus
fulgidus) 		3 / 3 TYR A 203
ARG A  15
SER A 246
 None
 1.01A 4lf8I-2voaA:
undetectable
4lf8J-2voaA:
undetectable		 4lf8I-2voaA:
20.88
4lf8J-2voaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2voa EXODEOXYRIBONUCLEASE
III
(Archaeoglobus
fulgidus) 		4 / 5 TYR A 201
LEU A 251
ASP A 155
VAL A 106
 None
 1.27A 4nkvA-2voaA:
undetectable		 4nkvA-2voaA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 2voa EXODEOXYRIBONUCLEASE
III
(Archaeoglobus
fulgidus) 		4 / 6 ILE A 154
ARG A 189
ILE A 197
GLU A 195
 None
 1.38A 4zzcA-2voaA:
undetectable
4zzcB-2voaA:
undetectable		 4zzcA-2voaA:
22.75
4zzcB-2voaA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 2voa EXODEOXYRIBONUCLEASE
III
(Archaeoglobus
fulgidus) 		5 / 12 HIS A 165
ASP A 218
HIS A 248
ASP A 146
GLY A 217
 OCS  A 167 ( 4.1A)
None
None
None
None
 1.19A 5eenA-2voaA:
undetectable		 5eenA-2voaA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2voa EXODEOXYRIBONUCLEASE
III
(Archaeoglobus
fulgidus) 		4 / 7 SER A 139
THR A 223
PHE A 184
ILE A   4
 None
 1.14A 5vkqA-2voaA:
undetectable
5vkqB-2voaA:
undetectable		 5vkqA-2voaA:
9.06
5vkqB-2voaA:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2voa EXODEOXYRIBONUCLEASE
III
(Archaeoglobus
fulgidus) 		4 / 8 SER A 139
THR A 223
PHE A 184
ILE A   4
 None
 1.13A 5vkqB-2voaA:
undetectable
5vkqC-2voaA:
undetectable		 5vkqB-2voaA:
9.06
5vkqC-2voaA:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2voa EXODEOXYRIBONUCLEASE
III
(Archaeoglobus
fulgidus) 		4 / 7 SER A 139
THR A 223
PHE A 184
ILE A   4
 None
 1.12A 5vkqC-2voaA:
undetectable
5vkqD-2voaA:
undetectable		 5vkqC-2voaA:
9.06
5vkqD-2voaA:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 2voa EXODEOXYRIBONUCLEASE
III
(Archaeoglobus
fulgidus) 		4 / 8 ILE A 102
PRO A 225
THR A 223
PHE A 137
 None
 1.12A 5x23A-2voaA:
undetectable		 5x23A-2voaA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AJI_A_AY6A1001_0
(DRUG EXPORTERS OF
THE RND
SUPERFAMILY-LIKE
PROTEIN,ENDOLYSIN)		 2voa EXODEOXYRIBONUCLEASE
III
(Archaeoglobus
fulgidus) 		5 / 12 VAL A 231
VAL A 257
VAL A 185
ALA A 222
LEU A 226
 None
 1.17A 6ajiA-2voaA:
undetectable		 6ajiA-2voaA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 2voa EXODEOXYRIBONUCLEASE
III
(Archaeoglobus
fulgidus) 		4 / 8 VAL A  55
GLN A  34
ASN A 103
ILE A  92
 None
 0.80A 6hzpA-2voaA:
undetectable		 6hzpA-2voaA:
20.00