SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vod'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_4
(POL POLYPROTEIN)		 2vod LUPUS LA PROTEIN
(Homo
sapiens) 		3 / 3 ARG A  57
VAL A 156
GLY A 135
 None
 0.35A 2avvE-2vodA:
undetectable		 2avvE-2vodA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 2vod LUPUS LA PROTEIN
(Homo
sapiens) 		6 / 12 GLN A  39
GLY A  45
ASP A  33
LEU A  30
ASN A  29
GLU A  81
 None
None
U  C  -1 ( 2.8A)
None
U  C  -1 ( 4.1A)
None
 1.47A 2zw9B-2vodA:
undetectable		 2zw9B-2vodA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 2vod LUPUS LA PROTEIN
(Homo
sapiens) 		5 / 9 PHE A 118
LEU A 131
VAL A 156
LEU A 180
ILE A 115
 None
 0.81A 3tbgD-2vodA:
undetectable		 3tbgD-2vodA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 2vod LUPUS LA PROTEIN
(Homo
sapiens) 		4 / 8 ILE A  40
ASP A  27
GLY A  26
PHE A  25
 None
 0.88A 4iqqD-2vodA:
undetectable		 4iqqD-2vodA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 2vod LUPUS LA PROTEIN
(Homo
sapiens) 		4 / 8 ILE A  40
ASP A  27
GLY A  26
PHE A  25
 None
 0.90A 5nooD-2vodA:
undetectable		 5nooD-2vodA:
20.58