SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vou'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3004_0
(BETA-CARBONIC
ANHYDRASE)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 6 GLN A 222
TYR A 206
VAL A  49
GLY A  47
 GOL  A1396 ( 2.8A)
GOL  A1396 (-4.8A)
FAD  A1395 (-3.7A)
None
 1.14A 1ekjC-2vouA:
undetectable
1ekjD-2vouA:
undetectable		 1ekjC-2vouA:
21.66
1ekjD-2vouA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3007_0
(BETA-CARBONIC
ANHYDRASE)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 6 VAL A  49
GLY A  47
GLN A 222
TYR A 206
 FAD  A1395 (-3.7A)
None
GOL  A1396 ( 2.8A)
GOL  A1396 (-4.8A)
 1.15A 1ekjC-2vouA:
undetectable
1ekjD-2vouA:
undetectable		 1ekjC-2vouA:
21.66
1ekjD-2vouA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 6 GLY A 305
ASP A 325
GLY A 354
TYR A 357
 FAD  A1395 (-3.5A)
None
None
ACT  A1397 (-4.5A)
 0.83A 1eswA-2vouA:
undetectable		 1eswA-2vouA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 8 PHE A 193
TYR A 195
ILE A 204
PHE A 374
 None
None
GOL  A1396 ( 4.4A)
None
 0.89A 1fslB-2vouA:
undetectable		 1fslB-2vouA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		3 / 3 ALA A 317
VAL A  50
TRP A  93
 FAD  A1395 ( 4.5A)
None
None
 0.77A 1grmA-2vouA:
undetectable		 1grmA-2vouA:
3.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		3 / 3 ALA A 317
VAL A  50
TRP A  93
 FAD  A1395 ( 4.5A)
None
None
 0.77A 1grmB-2vouA:
undetectable		 1grmB-2vouA:
3.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		3 / 3 ALA A 317
VAL A  50
TRP A  93
 FAD  A1395 ( 4.5A)
None
None
 0.91A 1jo4A-2vouA:
undetectable		 1jo4A-2vouA:
3.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		3 / 3 ALA A 317
VAL A  50
TRP A  93
 FAD  A1395 ( 4.5A)
None
None
 0.91A 1jo4B-2vouA:
undetectable		 1jo4B-2vouA:
3.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA8_0
(GRAMICIDIN A)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 4 VAL A 287
TRP A 172
VAL A 285
TRP A 225
 None
 1.15A 1micA-2vouA:
undetectable
1micB-2vouA:
undetectable		 1micA-2vouA:
3.56
1micB-2vouA:
3.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_B_DVAB8_0
(GRAMICIDIN A)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 5 VAL A 285
TRP A 225
VAL A 287
TRP A 172
 None
 1.39A 1micA-2vouA:
undetectable
1micB-2vouA:
undetectable		 1micA-2vouA:
3.56
1micB-2vouA:
3.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 4 LEU A 385
GLY A 319
ASP A 306
TYR A 357
 None
FAD  A1395 (-3.3A)
FAD  A1395 (-2.9A)
ACT  A1397 (-4.5A)
 1.16A 1oxrA-2vouA:
0.6		 1oxrA-2vouA:
15.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		3 / 3 PRO A 311
GLY A 318
TYR A 357
 ACT  A1397 (-4.1A)
FAD  A1395 ( 3.3A)
ACT  A1397 (-4.5A)
 0.02A 2vouA-2vouA:
72.1		 2vouA-2vouA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		3 / 3 PRO A 311
GLY A 318
TYR A 357
 ACT  A1397 (-4.1A)
FAD  A1395 ( 3.3A)
ACT  A1397 (-4.5A)
 0.21A 2vouB-2vouA:
67.7		 2vouB-2vouA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		3 / 3 PRO A 311
GLY A 318
TYR A 357
 ACT  A1397 (-4.1A)
FAD  A1395 ( 3.3A)
ACT  A1397 (-4.5A)
 0.21A 2vouC-2vouA:
67.6		 2vouC-2vouA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_A_RBFA200_1
(DODECIN)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 8 ARG A 295
ARG A 340
HIS A 298
GLN A 125
 None
 1.44A 2vxaA-2vouA:
undetectable
2vxaC-2vouA:
undetectable
2vxaE-2vouA:
undetectable		 2vxaA-2vouA:
13.33
2vxaC-2vouA:
13.33
2vxaE-2vouA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 8 ARG A 340
ARG A 295
HIS A 298
GLN A 125
 None
 1.39A 2vxaA-2vouA:
undetectable
2vxaB-2vouA:
undetectable
2vxaK-2vouA:
undetectable		 2vxaA-2vouA:
13.33
2vxaB-2vouA:
13.33
2vxaK-2vouA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_C_RBFC200_1
(DODECIN)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 8 ARG A 340
ARG A 295
HIS A 298
GLN A 125
 None
 1.40A 2vxaB-2vouA:
undetectable
2vxaC-2vouA:
undetectable
2vxaG-2vouA:
undetectable		 2vxaB-2vouA:
13.33
2vxaC-2vouA:
13.33
2vxaG-2vouA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_D_RBFD200_1
(DODECIN)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 8 ARG A 295
ARG A 340
HIS A 298
GLN A 125
 None
 1.41A 2vxaD-2vouA:
undetectable
2vxaF-2vouA:
undetectable
2vxaI-2vouA:
undetectable		 2vxaD-2vouA:
13.33
2vxaF-2vouA:
13.33
2vxaI-2vouA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_E_RBFE200_1
(DODECIN)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 8 ARG A 340
ARG A 295
HIS A 298
GLN A 125
 None
 1.37A 2vxaD-2vouA:
undetectable
2vxaE-2vouA:
undetectable
2vxaL-2vouA:
undetectable		 2vxaD-2vouA:
13.33
2vxaE-2vouA:
13.33
2vxaL-2vouA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_H_RBFH200_1
(DODECIN)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 8 HIS A 298
GLN A 125
ARG A 340
ARG A 295
 None
 1.44A 2vxaB-2vouA:
undetectable
2vxaG-2vouA:
undetectable
2vxaH-2vouA:
undetectable		 2vxaB-2vouA:
13.33
2vxaG-2vouA:
13.33
2vxaH-2vouA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_I_RBFI200_1
(DODECIN)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 8 ARG A 340
ARG A 295
HIS A 298
GLN A 125
 None
 1.39A 2vxaH-2vouA:
undetectable
2vxaI-2vouA:
undetectable
2vxaJ-2vouA:
undetectable		 2vxaH-2vouA:
13.33
2vxaI-2vouA:
13.33
2vxaJ-2vouA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_J_RBFJ200_1
(DODECIN)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 8 HIS A 298
GLN A 125
ARG A 295
ARG A 340
 None
 1.37A 2vxaD-2vouA:
undetectable
2vxaJ-2vouA:
undetectable
2vxaL-2vouA:
undetectable		 2vxaD-2vouA:
13.33
2vxaJ-2vouA:
13.33
2vxaL-2vouA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_K_RBFK200_1
(DODECIN)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 8 HIS A 298
GLN A 125
ARG A 340
ARG A 295
 None
 1.39A 2vxaH-2vouA:
undetectable
2vxaJ-2vouA:
undetectable
2vxaK-2vouA:
undetectable		 2vxaH-2vouA:
13.33
2vxaJ-2vouA:
13.33
2vxaK-2vouA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_L_RBFL200_1
(DODECIN)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 8 HIS A 298
GLN A 125
ARG A 340
ARG A 295
 None
 1.37A 2vxaA-2vouA:
undetectable
2vxaK-2vouA:
undetectable
2vxaL-2vouA:
undetectable		 2vxaA-2vouA:
13.33
2vxaK-2vouA:
13.33
2vxaL-2vouA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 GLY A  17
GLY A  13
ALA A 326
ARG A 327
LEU A  22
 None
FAD  A1395 ( 4.7A)
None
None
None
 0.98A 2yqzA-2vouA:
undetectable		 2yqzA-2vouA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 4 SER A  16
GLY A  17
GLY A 305
GLY A 150
 FAD  A1395 (-2.6A)
None
FAD  A1395 (-3.5A)
FAD  A1395 (-3.3A)
 0.92A 3bogB-2vouA:
undetectable
3bogD-2vouA:
undetectable		 3bogB-2vouA:
undetectable
3bogD-2vouA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 LEU A  41
PRO A 164
GLY A 150
GLY A  13
SER A  14
 FAD  A1395 (-4.5A)
None
FAD  A1395 (-3.3A)
FAD  A1395 ( 4.7A)
FAD  A1395 (-2.8A)
 1.11A 3e23A-2vouA:
3.1		 3e23A-2vouA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 PHE A 383
ILE A 204
TYR A 206
GLN A 222
THR A 171
 None
GOL  A1396 ( 4.4A)
GOL  A1396 (-4.8A)
GOL  A1396 ( 2.8A)
FAD  A1395 ( 4.7A)
 1.30A 3elzC-2vouA:
undetectable		 3elzC-2vouA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 THR A 138
PHE A 134
VAL A 145
GLN A 131
THR A 129
 None
 1.47A 3em0A-2vouA:
0.8		 3em0A-2vouA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 8 PHE A 262
LEU A 269
PHE A 221
LEU A 203
 None
 0.89A 3i45A-2vouA:
undetectable		 3i45A-2vouA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		5 / 9 GLY A 319
ALA A 322
ASP A 325
GLY A 150
LEU A  18
 FAD  A1395 (-3.3A)
FAD  A1395 ( 3.9A)
None
FAD  A1395 (-3.3A)
None
 0.92A 3u7sB-2vouA:
undetectable		 3u7sB-2vouA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 GLY A  17
ALA A  21
ALA A 330
ASP A 325
ALA A 322
 None
None
None
None
FAD  A1395 ( 3.9A)
 1.25A 4df3A-2vouA:
3.8		 4df3A-2vouA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 8 ILE A 101
ALA A 322
GLU A  53
VAL A  50
 None
FAD  A1395 ( 3.9A)
None
None
 0.81A 4jltA-2vouA:
undetectable		 4jltA-2vouA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		3 / 3 ASP A  99
GLU A 215
SER A  37
 None
 0.73A 5bw4B-2vouA:
3.7		 5bw4B-2vouA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 5 ASP A 325
VAL A 388
GLY A 354
ALA A 356
 None
 1.02A 5hwaA-2vouA:
undetectable		 5hwaA-2vouA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 7 VAL A 130
ALA A 142
LEU A 123
LEU A 120
 None
None
None
FAD  A1395 (-4.6A)
 0.62A 5jq7A-2vouA:
undetectable		 5jq7A-2vouA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 ALA A 326
LEU A 329
ALA A 330
PHE A 333
THR A 334
 None
 0.66A 5k9dA-2vouA:
undetectable		 5k9dA-2vouA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M10_A_NCAA603_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 2vou 2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE
(Paenarthrobacter
nicotinovorans) 		4 / 5 LEU A 269
PHE A 262
LEU A 278
TRP A 223
 None
 0.91A 5m10A-2vouA:
7.6		 5m10A-2vouA:
23.57