SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vpv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 2vpv PROTEIN MIF2
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 439
ALA A 440
LEU A 441
SER A 469
 None
 1.06A 1sbrA-2vpvA:
undetectable
1sbrB-2vpvA:
undetectable		 1sbrA-2vpvA:
17.50
1sbrB-2vpvA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 2vpv PROTEIN MIF2
(Saccharomyces
cerevisiae) 		3 / 3 MET A 522
MET A 444
PHE A 439
 None
 1.19A 3gn8A-2vpvA:
undetectable		 3gn8A-2vpvA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1C_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 2vpv PROTEIN MIF2
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 476
PHE A 478
ILE A 443
LEU A 457
SER A 469
 None
 1.20A 3o1cA-2vpvA:
undetectable		 3o1cA-2vpvA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 2vpv PROTEIN MIF2
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 476
PHE A 478
ILE A 443
LEU A 457
SER A 469
 None
 1.22A 3o1xA-2vpvA:
undetectable		 3o1xA-2vpvA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 2vpv PROTEIN MIF2
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 476
PHE A 478
ILE A 443
LEU A 457
SER A 469
 None
 1.20A 3qgzA-2vpvA:
undetectable		 3qgzA-2vpvA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_B_15UB301_1
(THROMBIN HEAVY CHAIN)		 2vpv PROTEIN MIF2
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 520
ALA A 513
VAL A 485
GLY A 516
GLY A 483
 None
 0.97A 4rn6B-2vpvA:
undetectable		 4rn6B-2vpvA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCO_A_FY5A1003_0
(ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
2)		 2vpv PROTEIN MIF2
(Saccharomyces
cerevisiae) 		5 / 11 PHE A 494
VAL A 489
THR A 501
VAL A 480
MET A 522
 None
 1.46A 6hcoA-2vpvA:
undetectable
6hcoB-2vpvA:
undetectable		 6hcoA-2vpvA:
13.55
6hcoB-2vpvA:
13.55