SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vq1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AQI_B_CHDB5_0 (FERROCHELATASE)	2vq1	ANTI-HUMAN FC GAMMA RECEPTOR III 3G8 GAMMA HEAVY CHAIN VARIABLE REGION (Mus musculus)	3 / 3	PRO B 9 LEU B 109 ARG B 38	None	0.82A	3aqiB-2vq1B: undetectable	3aqiB-2vq1B: 18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G1U_B_ADNB438_2 (ADENOSYLHOMOCYSTEINA SE)	2vq1	ANTI-HUMAN FC GAMMA RECEPTOR III 3G8 GAMMA HEAVY CHAIN VARIABLE REGION (Mus musculus)	3 / 3	THR B 87 GLU B 148 HIS B 199	None	0.84A	3g1uB-2vq1B: undetectable	3g1uB-2vq1B: 19.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4M93_B_ACTB305_0 (S25-26 FAB (IGG1K) HEAVY CHAIN)	2vq1	ANTI-HUMAN FC GAMMA RECEPTOR III 3G8 GAMMA HEAVY CHAIN VARIABLE REGION (Mus musculus)	4 / 4	SER B 19 THR B 21 PHE B 79 LYS B 81	None	0.81A	4m93B-2vq1B: 21.4	4m93B-2vq1B: 61.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECO_A_LEUA602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	2vq1	ANTI-HUMAN FC GAMMA RECEPTOR III 3G8 GAMMA HEAVY CHAIN VARIABLE REGION (Mus musculus)	4 / 6	THR B 87 ALA B 85 THR B 84 VAL B 83	None	0.99A	5ecoA-2vq1B: undetectable	5ecoA-2vq1B: 18.66

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3AQI_B_CHDB5_0","FERROCHELATASE","2vq1","ANTI-HUMAN FC GAMMA RECEPTOR III 3G8 GAMMA HEAVY CHAIN VARIABLE REGION","Mus musculus",3,"PRO B   9;LEU B 109;ARG B  38","None","0.82A","3aqiB-2vq1B:undetectable","3aqiB-2vq1B:18.94"],["3G1U_B_ADNB438_2","ADENOSYLHOMOCYSTEINASE","2vq1","ANTI-HUMAN FC GAMMA RECEPTOR III 3G8 GAMMA HEAVY CHAIN VARIABLE REGION","Mus musculus",3,"THR B  87;GLU B 148;HIS B 199","None","0.84A","3g1uB-2vq1B:undetectable","3g1uB-2vq1B:19.82"],["4M93_B_ACTB305_0","S25-26 FAB (IGG1K) HEAVY CHAIN","2vq1","ANTI-HUMAN FC GAMMA RECEPTOR III 3G8 GAMMA HEAVY CHAIN VARIABLE REGION","Mus musculus",4,"SER B  19;THR B  21;PHE B  79;LYS B  81","None","0.81A","4m93B-2vq1B:21.4","4m93B-2vq1B:61.82"],["5ECO_A_LEUA602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","2vq1","ANTI-HUMAN FC GAMMA RECEPTOR III 3G8 GAMMA HEAVY CHAIN VARIABLE REGION","Mus musculus",4,"THR B  87;ALA B  85;THR B  84;VAL B  83","None","0.99A","5ecoA-2vq1B:undetectable","5ecoA-2vq1B:18.66"]]