SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vq2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 2vq2 PUTATIVE FIMBRIAL
BIOGENESIS AND
TWITCHING MOTILITY
PROTEIN
(Neisseria
meningitidis) 		3 / 3 LEU A  42
TYR A  46
GLY A  49
 None
GOL  A1253 (-4.6A)
GOL  A1253 (-3.5A)
 0.55A 2ocuA-2vq2A:
undetectable		 2ocuA-2vq2A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 2vq2 PUTATIVE FIMBRIAL
BIOGENESIS AND
TWITCHING MOTILITY
PROTEIN
(Neisseria
meningitidis) 		4 / 8 ASN A 108
ALA A 143
GLY A 148
ILE A 149
 None
 0.71A 3so9A-2vq2A:
undetectable		 3so9A-2vq2A:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_2
(HIV-1 PROTEASE)		 2vq2 PUTATIVE FIMBRIAL
BIOGENESIS AND
TWITCHING MOTILITY
PROTEIN
(Neisseria
meningitidis) 		4 / 7 ASN A 108
ALA A 143
GLY A 148
ILE A 149
 None
 0.74A 3spkB-2vq2A:
undetectable		 3spkB-2vq2A:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 2vq2 PUTATIVE FIMBRIAL
BIOGENESIS AND
TWITCHING MOTILITY
PROTEIN
(Neisseria
meningitidis) 		3 / 3 TYR A 127
GLN A  90
TRP A 112
 None
 0.91A 4kn2C-2vq2A:
undetectable		 4kn2C-2vq2A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_D_MXMD606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2vq2 PUTATIVE FIMBRIAL
BIOGENESIS AND
TWITCHING MOTILITY
PROTEIN
(Neisseria
meningitidis) 		5 / 12 MET A  47
ILE A  59
VAL A  85
ALA A  89
SER A  92
 None
 1.34A 4m11D-2vq2A:
undetectable		 4m11D-2vq2A:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 2vq2 PUTATIVE FIMBRIAL
BIOGENESIS AND
TWITCHING MOTILITY
PROTEIN
(Neisseria
meningitidis) 		4 / 6 SER A 124
GLY A 116
ASN A 119
ILE A 149
 None
 1.11A 5j4nA-2vq2A:
undetectable		 5j4nA-2vq2A:
19.82