SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vq9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY5_A_ACTA600_0
(RIBONUCLEASE A)		 2vq9 RNASE 1
(Danio
rerio) 		4 / 4 HIS A  16
VAL A  47
ASN A  48
THR A  49
 CL  A1128 (-4.6A)
None
CL  A1128 ( 4.9A)
CL  A1128 (-4.2A)
 0.46A 1dy5A-2vq9A:
16.1		 1dy5A-2vq9A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 2vq9 RNASE 1
(Danio
rerio) 		4 / 5 PHE A  82
ILE A 109
GLY A  65
HIS A  57
 None
 1.03A 3r0lD-2vq9A:
undetectable		 3r0lD-2vq9A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2vq9 RNASE 1
(Danio
rerio) 		5 / 11 SER A  78
VAL A  17
PHE A  12
VAL A 111
HIS A  57
 None
 1.39A 3u9fN-2vq9A:
undetectable
3u9fO-2vq9A:
undetectable		 3u9fN-2vq9A:
26.22
3u9fO-2vq9A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_A_GAIA407_0
(PROTEIN (ARGINASE))		 2vq9 RNASE 1
(Danio
rerio) 		4 / 6 ARG A  94
HIS A  95
LEU A  89
ASP A  43
 None
 1.31A 4cevA-2vq9A:
undetectable
4cevB-2vq9A:
undetectable		 4cevA-2vq9A:
18.69
4cevB-2vq9A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_C_GAIC409_0
(PROTEIN (ARGINASE))		 2vq9 RNASE 1
(Danio
rerio) 		4 / 6 ASP A  43
ARG A  94
HIS A  95
LEU A  89
 None
 1.29A 4cevA-2vq9A:
undetectable
4cevC-2vq9A:
undetectable		 4cevA-2vq9A:
18.69
4cevC-2vq9A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_D_GAID410_0
(PROTEIN (ARGINASE))		 2vq9 RNASE 1
(Danio
rerio) 		4 / 6 ARG A  94
HIS A  95
LEU A  89
ASP A  43
 None
 1.28A 4cevD-2vq9A:
undetectable
4cevE-2vq9A:
undetectable		 4cevD-2vq9A:
18.69
4cevE-2vq9A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 2vq9 RNASE 1
(Danio
rerio) 		4 / 6 ARG A  94
HIS A  95
LEU A  89
ASP A  43
 None
 1.29A 4cevE-2vq9A:
undetectable
4cevF-2vq9A:
undetectable		 4cevE-2vq9A:
18.69
4cevF-2vq9A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 2vq9 RNASE 1
(Danio
rerio) 		4 / 7 LYS A 103
THR A  88
THR A  49
VAL A  47
 None
None
CL  A1128 (-4.2A)
None
 0.81A 4ik7A-2vq9A:
undetectable		 4ik7A-2vq9A:
18.71