SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vqa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 5 LEU A 138
LEU A 239
LEU A 253
GLY A 269
 None
None
ACT  A1395 (-4.8A)
None
 1.06A 1a4lC-2vqaA:
undetectable		 1a4lC-2vqaA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 TRP A 109
ALA A 107
VAL A 162
 None
 0.84A 1bdwA-2vqaA:
undetectable
1bdwB-2vqaA:
undetectable		 1bdwA-2vqaA:
3.14
1bdwB-2vqaA:
3.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KW0_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 VAL A 176
LEU A 100
LEU A 121
HIS A 103
GLU A 108
 None
None
None
MN  A1005 (-3.5A)
MN  A1005 (-2.5A)
 1.21A 1kw0A-2vqaA:
undetectable		 1kw0A-2vqaA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMK_A_H4BA1427_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 VAL A 176
LEU A 100
LEU A 121
HIS A 103
GLU A 108
 None
None
None
MN  A1005 (-3.5A)
MN  A1005 (-2.5A)
 1.25A 1mmkA-2vqaA:
undetectable		 1mmkA-2vqaA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 11 VAL A 176
LEU A 100
LEU A 121
HIS A 103
GLU A 108
 None
None
None
MN  A1005 (-3.5A)
MN  A1005 (-2.5A)
 1.23A 1mmtA-2vqaA:
undetectable		 1mmtA-2vqaA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_K_AG2K7002_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 7 GLU A 108
LEU A 161
LEU A  92
GLY A 151
 MN  A1005 (-2.5A)
None
None
None
 0.73A 1mt1H-2vqaA:
undetectable
1mt1K-2vqaA:
undetectable		 1mt1H-2vqaA:
13.47
1mt1K-2vqaA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 7 GLU A 108
LEU A 161
LEU A  92
GLY A 151
 MN  A1005 (-2.5A)
None
None
None
 0.75A 1n13D-2vqaA:
undetectable
1n13E-2vqaA:
undetectable		 1n13D-2vqaA:
13.47
1n13E-2vqaA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_H_AG2H7012_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 6 GLU A 108
LEU A 161
LEU A  92
GLY A 151
 MN  A1005 (-2.5A)
None
None
None
 0.74A 1n13H-2vqaA:
undetectable
1n13K-2vqaA:
undetectable		 1n13H-2vqaA:
13.47
1n13K-2vqaA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 7 LEU A 161
LEU A  92
GLY A 151
GLU A 108
 None
None
None
MN  A1005 (-2.5A)
 0.76A 1n13G-2vqaA:
undetectable
1n13J-2vqaA:
undetectable		 1n13G-2vqaA:
11.14
1n13J-2vqaA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 151
THR A 117
ALA A 215
SER A 216
GLY A  69
 None
 1.09A 1nbiC-2vqaA:
undetectable		 1nbiC-2vqaA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 GLU A 290
HIS A 329
HIS A 285
 MN  A1006 ( 2.3A)
MN  A1006 (-3.5A)
MN  A1006 ( 3.5A)
 0.66A 1oe2A-2vqaA:
undetectable		 1oe2A-2vqaA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A 329
GLU A 290
HIS A 285
HIS A 283
 MN  A1006 (-3.5A)
MN  A1006 ( 2.3A)
MN  A1006 ( 3.5A)
MN  A1006 ( 3.4A)
 1.14A 1os2D-2vqaA:
undetectable		 1os2D-2vqaA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVU_A_PRLA196_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 6 GLU A 108
TRP A 139
THR A 117
TYR A 208
 MN  A1005 (-2.5A)
None
None
None
 1.36A 1qvuA-2vqaA:
undetectable		 1qvuA-2vqaA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 7 GLN A  73
ALA A  86
PHE A  58
GLU A 170
 None
None
None
MN  A1005 ( 4.9A)
 1.12A 1t9wA-2vqaA:
undetectable		 1t9wA-2vqaA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 HIS A 283
LEU A 301
HIS A 329
VAL A 343
PHE A 345
 MN  A1006 ( 3.4A)
None
MN  A1006 (-3.5A)
None
None
 0.77A 1uobA-2vqaA:
3.9		 1uobA-2vqaA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A 329
GLU A 290
HIS A 285
HIS A 283
 MN  A1006 (-3.5A)
MN  A1006 ( 2.3A)
MN  A1006 ( 3.5A)
MN  A1006 ( 3.4A)
 1.16A 1utzA-2vqaA:
undetectable		 1utzA-2vqaA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 ASP A 349
TYR A 350
GLU A 260
 None
ACT  A1395 (-4.4A)
None
 0.78A 1vm1A-2vqaA:
undetectable		 1vm1A-2vqaA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 6 ILE A 272
HIS A 283
HIS A 329
HIS A 285
 None
MN  A1006 ( 3.4A)
MN  A1006 (-3.5A)
MN  A1006 ( 3.5A)
 0.89A 1y93A-2vqaA:
undetectable		 1y93A-2vqaA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 6 ILE A 272
HIS A 329
GLU A 290
HIS A 285
HIS A 283
 None
MN  A1006 (-3.5A)
MN  A1006 ( 2.3A)
MN  A1006 ( 3.5A)
MN  A1006 ( 3.4A)
 1.07A 1y93A-2vqaA:
undetectable		 1y93A-2vqaA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 HIS A 235
THR A 236
THR A 228
THR A 223
ALA A 222
 None
 0.91A 2gluA-2vqaA:
undetectable		 2gluA-2vqaA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 HIS A 235
THR A 236
THR A 228
THR A 223
ALA A 222
 None
 0.86A 2gluB-2vqaA:
undetectable		 2gluB-2vqaA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A 329
GLU A 290
HIS A 285
HIS A 283
 MN  A1006 (-3.5A)
MN  A1006 ( 2.3A)
MN  A1006 ( 3.5A)
MN  A1006 ( 3.4A)
 1.15A 2ow9B-2vqaA:
undetectable		 2ow9B-2vqaA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A 329
GLU A 290
HIS A 285
HIS A 283
 MN  A1006 (-3.5A)
MN  A1006 ( 2.3A)
MN  A1006 ( 3.5A)
MN  A1006 ( 3.4A)
 1.14A 2ozrC-2vqaA:
undetectable		 2ozrC-2vqaA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS A 329
GLU A 290
HIS A 285
HIS A 283
 MN  A1006 (-3.5A)
MN  A1006 ( 2.3A)
MN  A1006 ( 3.5A)
MN  A1006 ( 3.4A)
 1.11A 2ozrD-2vqaA:
undetectable		 2ozrD-2vqaA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 103
HIS A 147
HIS A 101
 MN  A1005 (-3.5A)
MN  A1005 (-3.5A)
MN  A1005 (-3.3A)
 0.75A 3abkA-2vqaA:
undetectable		 3abkA-2vqaA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 103
HIS A 147
HIS A 101
 MN  A1005 (-3.5A)
MN  A1005 (-3.5A)
MN  A1005 (-3.3A)
 0.74A 3abkN-2vqaA:
undetectable		 3abkN-2vqaA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 103
HIS A 147
HIS A 101
 MN  A1005 (-3.5A)
MN  A1005 (-3.5A)
MN  A1005 (-3.3A)
 0.74A 3ag1A-2vqaA:
undetectable		 3ag1A-2vqaA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 103
HIS A 147
HIS A 101
 MN  A1005 (-3.5A)
MN  A1005 (-3.5A)
MN  A1005 (-3.3A)
 0.75A 3ag2N-2vqaA:
undetectable		 3ag2N-2vqaA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 103
HIS A 147
HIS A 101
 MN  A1005 (-3.5A)
MN  A1005 (-3.5A)
MN  A1005 (-3.3A)
 0.76A 3ag3A-2vqaA:
undetectable		 3ag3A-2vqaA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 TYR A 350
GLY A 269
GLY A 348
SER A 257
HIS A 285
 ACT  A1395 (-4.4A)
None
None
None
MN  A1006 ( 3.5A)
 1.13A 3ou6B-2vqaA:
undetectable		 3ou6B-2vqaA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3C_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 103
HIS A 147
HIS A 101
 MN  A1005 (-3.5A)
MN  A1005 (-3.5A)
MN  A1005 (-3.3A)
 0.79A 3s3cA-2vqaA:
undetectable		 3s3cA-2vqaA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 103
HIS A 147
HIS A 101
 MN  A1005 (-3.5A)
MN  A1005 (-3.5A)
MN  A1005 (-3.3A)
 0.75A 3x2qA-2vqaA:
undetectable		 3x2qA-2vqaA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_B_HAEB1270_1
(COLLAGENASE 3)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 5 LEU A 253
HIS A 329
GLU A 290
HIS A 285
 ACT  A1395 (-4.8A)
MN  A1006 (-3.5A)
MN  A1006 ( 2.3A)
MN  A1006 ( 3.5A)
 1.31A 4a7bB-2vqaA:
undetectable		 4a7bB-2vqaA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 ARG A  98
HIS A 101
TYR A 208
 None
MN  A1005 (-3.3A)
None
 1.26A 4fu8A-2vqaA:
undetectable		 4fu8A-2vqaA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 ARG A  98
HIS A 101
TYR A 208
 None
MN  A1005 (-3.3A)
None
 1.20A 4fu9A-2vqaA:
undetectable		 4fu9A-2vqaA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 6 LEU A  92
HIS A 101
HIS A 147
GLU A 108
 None
MN  A1005 (-3.3A)
MN  A1005 (-3.5A)
MN  A1005 (-2.5A)
 1.13A 4pahA-2vqaA:
undetectable		 4pahA-2vqaA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 171
GLU A 170
PRO A 203
LEU A 180
HIS A 182
 None
MN  A1005 ( 4.9A)
None
None
None
 1.15A 4wcxC-2vqaA:
undetectable		 4wcxC-2vqaA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 4 GLY A 321
VAL A 294
PHE A 388
ILE A 272
 None
 0.90A 4xv2B-2vqaA:
undetectable		 4xv2B-2vqaA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 ASP A 340
GLU A 114
SER A 247
 None
 0.85A 5bw4B-2vqaA:
undetectable		 5bw4B-2vqaA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 MET A 279
GLN A 281
ARG A 280
 None
None
ACT  A1395 (-4.1A)
 1.10A 5ewzB-2vqaA:
undetectable		 5ewzB-2vqaA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 PHE A 159
GLY A 151
HIS A 101
TYR A 208
LEU A 161
 None
None
MN  A1005 (-3.3A)
None
None
 1.36A 5ji0D-2vqaA:
undetectable		 5ji0D-2vqaA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 5 GLY A 166
THR A 167
GLY A 297
LEU A 160
 None
 0.69A 5jlcA-2vqaA:
undetectable		 5jlcA-2vqaA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 MET A 279
GLN A 281
ARG A 280
 None
None
ACT  A1395 (-4.1A)
 0.98A 5m35B-2vqaA:
undetectable		 5m35B-2vqaA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 MET A 279
GLN A 281
ARG A 280
 None
None
ACT  A1395 (-4.1A)
 0.94A 5m36A-2vqaA:
undetectable		 5m36A-2vqaA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 5 ILE A 272
HIS A 283
HIS A 329
HIS A 285
 None
MN  A1006 ( 3.4A)
MN  A1006 (-3.5A)
MN  A1006 ( 3.5A)
 0.94A 5n5kA-2vqaA:
undetectable		 5n5kA-2vqaA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 5 ILE A 272
HIS A 329
GLU A 290
HIS A 285
HIS A 283
 None
MN  A1006 (-3.5A)
MN  A1006 ( 2.3A)
MN  A1006 ( 3.5A)
MN  A1006 ( 3.4A)
 1.05A 5n5kA-2vqaA:
undetectable		 5n5kA-2vqaA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 7 GLY A 297
HIS A 273
ASP A 340
ASN A 333
 None
 0.82A 5nnwD-2vqaA:
undetectable		 5nnwD-2vqaA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 7 GLY A 297
HIS A 273
ASP A 340
ASN A 333
 None
 0.78A 5no9D-2vqaA:
undetectable		 5no9D-2vqaA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 103
HIS A 147
HIS A 101
 MN  A1005 (-3.5A)
MN  A1005 (-3.5A)
MN  A1005 (-3.3A)
 0.73A 5x19A-2vqaA:
undetectable		 5x19A-2vqaA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 103
HIS A 147
HIS A 101
 MN  A1005 (-3.5A)
MN  A1005 (-3.5A)
MN  A1005 (-3.3A)
 0.73A 5x1fA-2vqaA:
undetectable		 5x1fA-2vqaA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 283
HIS A 329
HIS A 285
 MN  A1006 ( 3.4A)
MN  A1006 (-3.5A)
MN  A1006 ( 3.5A)
 0.46A 5zrdA-2vqaA:
undetectable		 5zrdA-2vqaA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 5 VAL A 133
THR A 117
VAL A 344
LEU A 271
 ACT  A1396 (-3.9A)
None
None
None
 0.97A 6bqgA-2vqaA:
undetectable		 6bqgA-2vqaA:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 MET A 279
GLN A 281
ARG A 280
 None
None
ACT  A1395 (-4.1A)
 0.96A 6fn9A-2vqaA:
undetectable		 6fn9A-2vqaA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 MET A 279
GLN A 281
ARG A 280
 None
None
ACT  A1395 (-4.1A)
 0.97A 6fnaB-2vqaA:
undetectable		 6fnaB-2vqaA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 MET A 279
GLN A 281
ARG A 280
 None
None
ACT  A1395 (-4.1A)
 0.95A 6fnbA-2vqaA:
undetectable		 6fnbA-2vqaA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 103
HIS A 147
HIS A 101
 MN  A1005 (-3.5A)
MN  A1005 (-3.5A)
MN  A1005 (-3.3A)
 0.73A 6giqa-2vqaA:
undetectable		 6giqa-2vqaA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 2vqa SLL1358 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 6 PRO A 124
TRP A 145
ILE A 231
GLY A 126
 None
 1.12A 6gqiA-2vqaA:
undetectable		 6gqiA-2vqaA:
20.00