SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vr3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 2vr3 CLUMPING FACTOR A
(Staphylococcus
aureus) 		4 / 7 HIS A 494
ASN A 423
THR A 431
GLY A 493
 None
 1.05A 2f6dA-2vr3A:
undetectable		 2f6dA-2vr3A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 2vr3 CLUMPING FACTOR A
(Staphylococcus
aureus) 		5 / 12 ASP A 405
ASN A 401
VAL A 400
GLY A 511
ILE A 380
 None
 0.93A 2f80B-2vr3A:
undetectable		 2f80B-2vr3A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 2vr3 CLUMPING FACTOR A
(Staphylococcus
aureus) 		5 / 12 GLY A 287
LEU A 283
VAL A 315
MET A 335
LEU A 333
 None
 1.00A 2nyuB-2vr3A:
undetectable		 2nyuB-2vr3A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 2vr3 CLUMPING FACTOR A
(Staphylococcus
aureus) 		3 / 3 ASP A 312
ASN A 314
THR A 233
 None
 0.76A 2q63B-2vr3A:
undetectable		 2q63B-2vr3A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 2vr3 CLUMPING FACTOR A
(Staphylococcus
aureus) 		6 / 12 LEU A 304
ALA A 331
ALA A 269
THR A 359
VAL A 241
ILE A 277
 None
 1.45A 3c6gA-2vr3A:
undetectable		 3c6gA-2vr3A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LBD_A_9CRA424_1
(RETINOIC ACID
RECEPTOR GAMMA)		 2vr3 CLUMPING FACTOR A
(Staphylococcus
aureus) 		5 / 12 PHE A 263
ALA A 331
LEU A 304
PHE A 275
GLY A 307
 None
 1.27A 3lbdA-2vr3A:
undetectable		 3lbdA-2vr3A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 2vr3 CLUMPING FACTOR A
(Staphylococcus
aureus) 		4 / 4 TYR A 394
GLY A 414
SER A 507
LEU A 505
 None
 1.39A 5bphC-2vr3A:
undetectable		 5bphC-2vr3A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_1
(PROTEIN CYP51)		 2vr3 CLUMPING FACTOR A
(Staphylococcus
aureus) 		5 / 12 ALA A 528
TYR A 261
ALA A 361
ALA A 353
LEU A 283
 None
 1.23A 5tl8A-2vr3A:
undetectable		 5tl8A-2vr3A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2vr3 CLUMPING FACTOR A
(Staphylococcus
aureus) 		4 / 5 ILE A 297
LEU A 304
THR A 233
LEU A 236
 None
 0.87A 6nmpN-2vr3A:
undetectable
6nmpW-2vr3A:
undetectable		 6nmpN-2vr3A:
20.08
6nmpW-2vr3A:
11.66