SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vsa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 8 PHE A 185
SER A  61
ILE A  64
LEU A  73
 None
 0.86A 1eupA-2vsaA:
undetectable		 1eupA-2vsaA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_A_HISA450_0
(HISTIDYL-TRNA
SYNTHETASE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 10 GLU A 301
THR A 440
ARG A 546
TYR A 442
GLY A 332
 None
 1.32A 1httA-2vsaA:
undetectable		 1httA-2vsaA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RI4_A_SAMA299_0
(MRNA CAPPING ENZYME)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 GLY A 178
ILE A 173
ALA A 175
PHE A 140
SER A 142
 None
 1.17A 1ri4A-2vsaA:
undetectable		 1ri4A-2vsaA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 11 LEU A  73
GLY A 203
GLY A 202
ILE A 139
ILE A 179
 None
 0.89A 1sduA-2vsaA:
undetectable		 1sduA-2vsaA:
8.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9U_A_CPFA5002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 6 PHE A 208
PHE A 229
ASN A 226
ASN A 536
 None
 1.29A 1t9uA-2vsaA:
undetectable		 1t9uA-2vsaA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 ILE A 204
ILE A 209
ARG A 205
ILE A  89
PHE A 107
 None
 1.22A 1xzxX-2vsaA:
undetectable		 1xzxX-2vsaA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 9 THR A 848
LEU A 833
GLU A 813
ALA A 826
TYR A 809
 None
 1.44A 2azqA-2vsaA:
undetectable		 2azqA-2vsaA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 8 ALA A  44
PHE A 200
ALA A 175
LEU A  95
 None
 0.84A 2bxmA-2vsaA:
undetectable		 2bxmA-2vsaA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		3 / 3 ASP A 701
ASN A 700
THR A 595
 None
 0.54A 2pymB-2vsaA:
undetectable		 2pymB-2vsaA:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		3 / 3 ASP A 701
ASN A 700
THR A 595
 None
 0.59A 2q63B-2vsaA:
undetectable		 2q63B-2vsaA:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 6 PHE A 566
GLY A 570
GLY A 571
ASN A 573
 None
 1.01A 2qr2A-2vsaA:
undetectable
2qr2B-2vsaA:
undetectable		 2qr2A-2vsaA:
13.25
2qr2B-2vsaA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		3 / 3 TYR A 349
VAL A 296
THR A 388
 None
 0.69A 2ygnA-2vsaA:
undetectable		 2ygnA-2vsaA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 5 LEU A  55
ILE A 681
ARG A 683
TYR A 718
 None
 1.47A 2zlcA-2vsaA:
undetectable		 2zlcA-2vsaA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 8 ILE A  64
ASN A 860
SER A 735
SER A  66
 None
 1.08A 2zw9B-2vsaA:
undetectable		 2zw9B-2vsaA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_0
(UNCHARACTERIZED
PROTEIN PH0793)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 SER A 725
ASN A 726
GLY A 589
HIS A 721
ILE A 638
 None
 1.45A 3a25A-2vsaA:
undetectable		 3a25A-2vsaA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 8 SER A 233
GLY A  85
GLU A 534
ILE A  87
 None
 0.92A 3aodA-2vsaA:
undetectable		 3aodA-2vsaA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 4 ILE A 437
GLN A 298
ILE A 351
LEU A 294
 None
 1.30A 3dzyD-2vsaA:
undetectable		 3dzyD-2vsaA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 11 GLY A 678
LEU A 120
ASN A 117
LEU A  56
LEU A  55
 None
 1.21A 3ndvA-2vsaA:
undetectable
3ndvB-2vsaA:
undetectable		 3ndvA-2vsaA:
17.95
3ndvB-2vsaA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 11 LEU A  56
LEU A  55
GLY A 678
LEU A 120
ASN A 117
 None
 1.22A 3ndvA-2vsaA:
undetectable
3ndvB-2vsaA:
undetectable		 3ndvA-2vsaA:
17.95
3ndvB-2vsaA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 11 GLY A 678
LEU A 120
ASN A 117
LEU A  56
LEU A  55
 None
 1.20A 3ndvC-2vsaA:
undetectable
3ndvD-2vsaA:
undetectable		 3ndvC-2vsaA:
17.95
3ndvD-2vsaA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 11 LEU A  56
LEU A  55
GLY A 678
LEU A 120
ASN A 117
 None
 1.20A 3ndvC-2vsaA:
undetectable
3ndvD-2vsaA:
undetectable		 3ndvC-2vsaA:
17.95
3ndvD-2vsaA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 LEU A 359
GLY A 376
SER A 323
LEU A 361
TRP A 338
 None
 1.29A 3ou6C-2vsaA:
undetectable		 3ou6C-2vsaA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 LEU A 359
GLY A 376
SER A 323
LEU A 361
TRP A 338
 None
 1.24A 3ou6D-2vsaA:
undetectable		 3ou6D-2vsaA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 LEU A 359
GLY A 376
SER A 323
LEU A 361
TRP A 338
 None
 1.26A 3ou7A-2vsaA:
undetectable		 3ou7A-2vsaA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 LEU A 359
GLY A 376
SER A 323
LEU A 361
TRP A 338
 None
 1.25A 3ou7C-2vsaA:
undetectable		 3ou7C-2vsaA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 LEU A 359
GLY A 376
SER A 323
LEU A 361
TRP A 338
 None
 1.25A 3ou7D-2vsaA:
undetectable		 3ou7D-2vsaA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 ASP A 273
ILE A 139
ASP A 105
ASP A  99
ARG A  97
 None
 1.02A 3phaB-2vsaA:
undetectable		 3phaB-2vsaA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_C_ACRC701_1
(ALPHA-GLUCOSIDASE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 ASP A 273
ILE A 139
ASP A 105
ASP A  99
ARG A  97
 None
 0.99A 3phaC-2vsaA:
undetectable		 3phaC-2vsaA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 ASP A 273
ILE A 139
ASP A 105
ASP A  99
ARG A  97
 None
 1.01A 3phaD-2vsaA:
undetectable		 3phaD-2vsaA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 5 ILE A 173
THR A 143
THR A 144
PHE A 200
 None
 1.21A 3snfA-2vsaA:
undetectable		 3snfA-2vsaA:
7.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 10 ALA A 706
GLY A 693
LEU A 648
ASN A 695
ILE A 612
 None
 0.97A 3wdmB-2vsaA:
undetectable		 3wdmB-2vsaA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 ASP A 656
GLN A 712
ILE A 691
PRO A 703
ILE A 658
 None
 1.10A 4drhD-2vsaA:
undetectable		 4drhD-2vsaA:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_C_TMQC202_1
(DIHYDROFOLATE
REDUCTASE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 ILE A 179
LEU A  56
LEU A  49
ILE A 139
THR A 143
 None
 1.01A 4m2xC-2vsaA:
undetectable		 4m2xC-2vsaA:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_C_TMQC202_1
(DIHYDROFOLATE
REDUCTASE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 ILE A 179
LEU A  56
LEU A  49
TYR A 131
THR A 143
 None
 1.01A 4m2xC-2vsaA:
undetectable		 4m2xC-2vsaA:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 8 VAL A 549
ILE A 577
VAL A 445
THR A 444
 None
 0.93A 4ma7A-2vsaA:
undetectable		 4ma7A-2vsaA:
8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 6 PHE A 248
ILE A 225
ARG A 210
VAL A 296
 None
 1.31A 4mk4B-2vsaA:
undetectable		 4mk4B-2vsaA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 5 ILE A 572
LEU A 456
ASP A 551
VAL A 452
 None
 1.06A 4nkxB-2vsaA:
undetectable		 4nkxB-2vsaA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		3 / 3 ASN A 231
SER A 233
ARG A 310
 None
 0.91A 5b2qA-2vsaA:
undetectable		 5b2qA-2vsaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 8 TYR A 527
ASP A 522
ILE A 490
TYR A 487
 None
 1.04A 5cfsA-2vsaA:
undetectable		 5cfsA-2vsaA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 GLY A 693
ILE A 612
ILE A 597
PHE A 593
LEU A 719
 None
 1.06A 5fa8A-2vsaA:
undetectable		 5fa8A-2vsaA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 SER A 425
GLY A 414
THR A 416
VAL A 423
LEU A 422
 None
 1.20A 5kocB-2vsaA:
undetectable		 5kocB-2vsaA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 4 GLN A 443
THR A 444
GLU A 207
LEU A 235
 None
 1.37A 5m66A-2vsaA:
undetectable		 5m66A-2vsaA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 12 GLY A 322
LEU A 422
LEU A 409
LEU A 361
LEU A 359
 None
 0.84A 5nfjA-2vsaA:
undetectable		 5nfjA-2vsaA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		3 / 3 HIS A 654
SER A 655
LYS A 657
 None
 1.46A 5os7A-2vsaA:
undetectable		 5os7A-2vsaA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 5 THR A 694
ASN A 714
TRP A 717
LEU A 648
 None
 1.40A 5vkqA-2vsaA:
undetectable
5vkqB-2vsaA:
undetectable		 5vkqA-2vsaA:
18.85
5vkqB-2vsaA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 5 THR A 694
ASN A 714
TRP A 717
LEU A 648
 None
 1.43A 5vkqB-2vsaA:
undetectable
5vkqC-2vsaA:
undetectable		 5vkqB-2vsaA:
18.85
5vkqC-2vsaA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 5 THR A 694
ASN A 714
TRP A 717
LEU A 648
 None
 1.44A 5vkqC-2vsaA:
undetectable
5vkqD-2vsaA:
undetectable		 5vkqC-2vsaA:
18.85
5vkqD-2vsaA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		5 / 9 LEU A  56
ILE A 139
GLY A 202
LEU A  46
ILE A 586
 None
 0.92A 5vkqC-2vsaA:
undetectable
5vkqD-2vsaA:
undetectable		 5vkqC-2vsaA:
18.85
5vkqD-2vsaA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		3 / 3 GLY A 240
ASN A 291
ARG A 170
 None
 0.71A 5w7bD-2vsaA:
undetectable		 5w7bD-2vsaA:
6.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 8 LEU A 422
VAL A 325
VAL A 314
ILE A 351
 None
 0.79A 5y9mA-2vsaA:
undetectable		 5y9mA-2vsaA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		4 / 5 ASP A 677
ILE A 673
ASN A 598
TYR A 718
 None
 0.98A 6a93B-2vsaA:
undetectable		 6a93B-2vsaA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		3 / 3 GLN A 857
TYR A 852
ASN A 854
 None
 0.72A 6dwdC-2vsaA:
undetectable		 6dwdC-2vsaA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		3 / 3 TYR A 669
ASP A 667
GLN A 668
 None
 0.95A 6g1pA-2vsaA:
undetectable		 6g1pA-2vsaA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_B_ACTB402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2vsa MOSQUITOCIDAL TOXIN
(Lysinibacillus
sphaericus) 		3 / 3 HIS A 654
SER A 655
LYS A 657
 None
 1.46A 6gmdB-2vsaA:
undetectable		 6gmdB-2vsaA:
16.96