SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vsk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 2vsk HEMAGGLUTININ-NEURAM
INIDASE
(Hendra
henipavirus) 		4 / 8 ASN A 482
LEU A 466
TYR A 454
SER A 457
 None
 1.07A 1hk3A-2vskA:
undetectable		 1hk3A-2vskA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_2
(THYMIDYLATE SYNTHASE)		 2vsk HEMAGGLUTININ-NEURAM
INIDASE
(Hendra
henipavirus) 		3 / 3 HIS A 281
ILE A 279
LEU A 234
 None
 0.76A 2kceA-2vskA:
undetectable		 2kceA-2vskA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2vsk HEMAGGLUTININ-NEURAM
INIDASE
(Hendra
henipavirus) 		4 / 8 THR A 437
SER A 457
TYR A 508
TYR A 454
 None
 1.28A 2xz5A-2vskA:
undetectable
2xz5C-2vskA:
undetectable		 2xz5A-2vskA:
19.41
2xz5C-2vskA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 2vsk HEMAGGLUTININ-NEURAM
INIDASE
(Hendra
henipavirus) 		5 / 12 ASN A 306
ILE A 438
SER A 411
GLN A 455
TRP A 504
 None
 1.42A 3bwmA-2vskA:
undetectable		 3bwmA-2vskA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 2vsk HEMAGGLUTININ-NEURAM
INIDASE
(Hendra
henipavirus) 		4 / 7 ILE A 356
GLY A 355
SER A 354
PHE A 512
 None
 0.79A 3v7pA-2vskA:
undetectable		 3v7pA-2vskA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 2vsk HEMAGGLUTININ-NEURAM
INIDASE
(Hendra
henipavirus) 		4 / 7 LEU A 198
TYR A 547
ILE A 514
GLY A 523
 None
 0.95A 4eq4A-2vskA:
undetectable		 4eq4A-2vskA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 2vsk HEMAGGLUTININ-NEURAM
INIDASE
(Hendra
henipavirus) 		4 / 7 LEU A 198
TYR A 547
ILE A 514
GLY A 523
 None
 0.95A 4eqlA-2vskA:
undetectable		 4eqlA-2vskA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 2vsk HEMAGGLUTININ-NEURAM
INIDASE
(Hendra
henipavirus) 		4 / 7 LEU A 198
TYR A 547
ILE A 514
GLY A 523
 None
 0.95A 4eqlB-2vskA:
undetectable		 4eqlB-2vskA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 2vsk HEMAGGLUTININ-NEURAM
INIDASE
(Hendra
henipavirus) 		4 / 6 LEU A 198
TYR A 547
ILE A 514
GLY A 523
 None
 0.89A 4l39A-2vskA:
undetectable		 4l39A-2vskA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 2vsk HEMAGGLUTININ-NEURAM
INIDASE
(Hendra
henipavirus) 		3 / 3 ASP A 585
VAL A 215
ASN A 557
 None
 0.66A 4lmnA-2vskA:
undetectable		 4lmnA-2vskA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 2vsk HEMAGGLUTININ-NEURAM
INIDASE
(Hendra
henipavirus) 		4 / 5 GLN A 559
THR A 507
THR A 563
LEU A 551
 None
 1.26A 4lvcC-2vskA:
undetectable		 4lvcC-2vskA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 2vsk HEMAGGLUTININ-NEURAM
INIDASE
(Hendra
henipavirus) 		5 / 12 ASN A 306
ILE A 438
SER A 411
GLN A 455
TRP A 504
 None
 1.39A 4xueA-2vskA:
undetectable		 4xueA-2vskA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSA_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 2vsk HEMAGGLUTININ-NEURAM
INIDASE
(Hendra
henipavirus) 		5 / 12 ASN A 306
ILE A 438
SER A 411
GLN A 455
TRP A 504
 None
 1.38A 5lsaA-2vskA:
undetectable		 5lsaA-2vskA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2vsk HEMAGGLUTININ-NEURAM
INIDASE
(Hendra
henipavirus) 		4 / 4 GLN A 559
THR A 507
THR A 563
LEU A 551
 None
 1.24A 5m5kA-2vskA:
undetectable		 5m5kA-2vskA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2vsk HEMAGGLUTININ-NEURAM
INIDASE
(Hendra
henipavirus) 		4 / 4 GLN A 559
THR A 507
THR A 563
LEU A 551
 None
 1.24A 5m5kC-2vskA:
undetectable		 5m5kC-2vskA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2vsk HEMAGGLUTININ-NEURAM
INIDASE
(Hendra
henipavirus) 		4 / 4 GLN A 559
THR A 507
THR A 563
LEU A 551
 None
 1.30A 5m66B-2vskA:
undetectable		 5m66B-2vskA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2vsk HEMAGGLUTININ-NEURAM
INIDASE
(Hendra
henipavirus) 		3 / 3 GLU A 235
HIS A 233
ARG A 248
 None
 0.99A 5uunA-2vskA:
undetectable		 5uunA-2vskA:
21.07