SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vsm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_1
(HIV-1 PROTEASE)		 2vsm HEMAGGLUTININ-NEURAM
INIDASE
(Nipah
henipavirus) 		5 / 9 GLY A 523
ASP A 510
ILE A 520
VAL A 484
ILE A 485
 None
 1.06A 1hxwA-2vsmA:
undetectable		 1hxwA-2vsmA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_2
(PHOSPHOLIPASE A2
HOMOLOG 2)		 2vsm HEMAGGLUTININ-NEURAM
INIDASE
(Nipah
henipavirus) 		5 / 11 LEU A 592
LEU A 577
VAL A 255
GLY A 253
TYR A 231
 None
 1.48A 1y4lB-2vsmA:
undetectable		 1y4lB-2vsmA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 2vsm HEMAGGLUTININ-NEURAM
INIDASE
(Nipah
henipavirus) 		4 / 8 GLY A 400
THR A 308
ILE A 401
SER A 405
 None
 0.98A 2a8tB-2vsmA:
undetectable		 2a8tB-2vsmA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2vsm HEMAGGLUTININ-NEURAM
INIDASE
(Nipah
henipavirus) 		5 / 12 SER A 411
VAL A 367
THR A 308
ILE A 304
PHE A 369
 None
 1.20A 2vdyA-2vsmA:
undetectable		 2vdyA-2vsmA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 2vsm HEMAGGLUTININ-NEURAM
INIDASE
(Nipah
henipavirus) 		3 / 3 ARG A 410
GLY A 439
SER A 307
 None
 0.60A 2xctB-2vsmA:
undetectable		 2xctB-2vsmA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 2vsm HEMAGGLUTININ-NEURAM
INIDASE
(Nipah
henipavirus) 		3 / 3 PRO A 598
LEU A 198
ARG A 548
 None
 0.85A 3aqiA-2vsmA:
undetectable		 3aqiA-2vsmA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 2vsm HEMAGGLUTININ-NEURAM
INIDASE
(Nipah
henipavirus) 		4 / 6 LEU A 265
TYR A 205
LEU A 207
LEU A 592
 None
 1.01A 3f33A-2vsmA:
undetectable		 3f33A-2vsmA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 2vsm HEMAGGLUTININ-NEURAM
INIDASE
(Nipah
henipavirus) 		4 / 5 LYS A 391
PRO A 392
SER A 380
LEU A 397
 None
 1.16A 3iluH-2vsmA:
undetectable		 3iluH-2vsmA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 2vsm HEMAGGLUTININ-NEURAM
INIDASE
(Nipah
henipavirus) 		4 / 7 ILE A 356
GLY A 355
SER A 354
PHE A 512
 None
 0.82A 3v7pA-2vsmA:
undetectable		 3v7pA-2vsmA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2vsm HEMAGGLUTININ-NEURAM
INIDASE
(Nipah
henipavirus) 		5 / 12 SER A 411
VAL A 367
THR A 308
ILE A 304
PHE A 369
 None
 1.19A 4c49B-2vsmA:
undetectable		 4c49B-2vsmA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2vsm HEMAGGLUTININ-NEURAM
INIDASE
(Nipah
henipavirus) 		5 / 12 SER A 411
VAL A 367
THR A 308
ILE A 304
PHE A 369
 None
 1.20A 4c49C-2vsmA:
undetectable		 4c49C-2vsmA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2vsm HEMAGGLUTININ-NEURAM
INIDASE
(Nipah
henipavirus) 		5 / 12 SER A 411
VAL A 367
THR A 308
ILE A 304
PHE A 369
 None
 1.30A 4c49D-2vsmA:
undetectable		 4c49D-2vsmA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 2vsm HEMAGGLUTININ-NEURAM
INIDASE
(Nipah
henipavirus) 		5 / 12 ILE A 431
THR A 471
VAL A 469
LEU A 413
TYR A 363
 None
 1.14A 4g1bD-2vsmA:
undetectable		 4g1bD-2vsmA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 2vsm HEMAGGLUTININ-NEURAM
INIDASE
(Nipah
henipavirus) 		4 / 6 LEU A 198
TYR A 547
ILE A 514
GLY A 523
 None
 1.00A 4l39A-2vsmA:
undetectable		 4l39A-2vsmA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 2vsm HEMAGGLUTININ-NEURAM
INIDASE
(Nipah
henipavirus) 		5 / 9 PRO A 273
LEU A 319
GLY A 251
VAL A 293
THR A 317
 None
 1.08A 4x3mA-2vsmA:
undetectable		 4x3mA-2vsmA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 2vsm HEMAGGLUTININ-NEURAM
INIDASE
(Nipah
henipavirus) 		5 / 9 PRO A 273
LEU A 319
GLY A 251
VAL A 293
THR A 317
 None
 1.05A 4x3mB-2vsmA:
undetectable		 4x3mB-2vsmA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 2vsm HEMAGGLUTININ-NEURAM
INIDASE
(Nipah
henipavirus) 		5 / 12 ASN A 306
ILE A 438
SER A 411
GLN A 455
TRP A 504
 None
 1.49A 4xueA-2vsmA:
undetectable		 4xueA-2vsmA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 2vsm HEMAGGLUTININ-NEURAM
INIDASE
(Nipah
henipavirus) 		4 / 5 PRO A 535
LEU A 222
TYR A 454
PHE A 466
 None
None
IPA  A1604 (-4.5A)
None
 1.39A 5igjA-2vsmA:
1.8		 5igjA-2vsmA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 2vsm HEMAGGLUTININ-NEURAM
INIDASE
(Nipah
henipavirus) 		4 / 8 SER A 576
THR A 563
THR A 561
PRO A 200
 None
 1.10A 5jhdE-2vsmA:
undetectable
5jhdG-2vsmA:
undetectable		 5jhdE-2vsmA:
24.06
5jhdG-2vsmA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2vsm HEMAGGLUTININ-NEURAM
INIDASE
(Nipah
henipavirus) 		3 / 3 GLU A 235
HIS A 233
ARG A 248
 None
 0.93A 5uunA-2vsmA:
undetectable		 5uunA-2vsmA:
20.05