SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vsv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_2
(PROTEIN (PROTEASE))		 2vsv RHOPHILIN-2
(Homo
sapiens) 		5 / 12 GLY A 551
ALA A 552
ASP A 556
ILE A 558
THR A 520
 None
 0.72A 1c6zB-2vsvA:
undetectable		 1c6zB-2vsvA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 2vsv RHOPHILIN-2
(Homo
sapiens) 		4 / 6 ASP A 556
TYR A 557
PHE A 519
LEU A 578
 None
 1.17A 2w98A-2vsvA:
undetectable
2w98B-2vsvA:
undetectable		 2w98A-2vsvA:
14.04
2w98B-2vsvA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 2vsv RHOPHILIN-2
(Homo
sapiens) 		5 / 10 ALA A 550
ILE A 517
ILE A 561
LEU A 578
ILE A 586
 None
 1.04A 4dtaA-2vsvA:
undetectable		 4dtaA-2vsvA:
16.36