SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vtw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 2vtw FIBER PROTEIN 2
(Fowl
aviadenovirus
A) 		6 / 12 LEU A 383
PHE A 277
LEU A 347
ILE A 352
ILE A 394
ALA A 393
 None
 1.25A 2bxqA-2vtwA:
undetectable		 2bxqA-2vtwA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 2vtw FIBER PROTEIN 2
(Fowl
aviadenovirus
A) 		4 / 5 PHE A 226
PHE A 234
PHE A 384
VAL A 255
 None
 1.27A 2lh6A-2vtwA:
undetectable		 2lh6A-2vtwA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_B_XRAB233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2vtw FIBER PROTEIN 2
(Fowl
aviadenovirus
A) 		5 / 11 VAL A 397
PHE A 277
PHE A 234
GLY A 224
ILE A 293
 None
 1.39A 3owxA-2vtwA:
undetectable
3owxB-2vtwA:
undetectable		 3owxA-2vtwA:
20.23
3owxB-2vtwA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 2vtw FIBER PROTEIN 2
(Fowl
aviadenovirus
A) 		4 / 6 GLY A 395
PRO A 396
LEU A 253
VAL A 397
 None
 0.92A 4dubB-2vtwA:
undetectable		 4dubB-2vtwA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_2
(THYROID HORMONE
RECEPTOR ALPHA)		 2vtw FIBER PROTEIN 2
(Fowl
aviadenovirus
A) 		3 / 3 ILE A 352
MET A 356
ARG A 355
 None
 0.95A 4lnxA-2vtwA:
undetectable		 4lnxA-2vtwA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2vtw FIBER PROTEIN 2
(Fowl
aviadenovirus
A) 		5 / 11 VAL A 397
PHE A 277
PHE A 234
GLY A 224
ILE A 293
 None
 1.39A 4zvmA-2vtwA:
undetectable
4zvmB-2vtwA:
undetectable		 4zvmA-2vtwA:
20.54
4zvmB-2vtwA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA607_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 2vtw FIBER PROTEIN 2
(Fowl
aviadenovirus
A) 		4 / 4 GLY A 390
ARG A 265
ASN A 389
LEU A 347
 None
 1.13A 6b58A-2vtwA:
undetectable		 6b58A-2vtwA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 2vtw FIBER PROTEIN 2
(Fowl
aviadenovirus
A) 		4 / 6 VAL A 358
ASN A 313
PRO A 314
ILE A 315
 None
 1.23A 6h7uA-2vtwA:
undetectable		 6h7uA-2vtwA:
18.65