SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vu5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 2vu5 NUCLEOSIDE
DIPHOSPHATE KINASE
(Bacillus
anthracis) 		4 / 8 ILE A 129
PHE A 130
VAL A  70
MET A  38
 None
 0.96A 1kb9A-2vu5A:
undetectable
1kb9C-2vu5A:
undetectable
1kb9D-2vu5A:
undetectable
1kb9E-2vu5A:
undetectable		 1kb9A-2vu5A:
16.24
1kb9C-2vu5A:
15.83
1kb9D-2vu5A:
19.44
1kb9E-2vu5A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 2vu5 NUCLEOSIDE
DIPHOSPHATE KINASE
(Bacillus
anthracis) 		3 / 3 TYR A 148
GLU A  78
THR A  83
 None
 0.98A 2y7hB-2vu5A:
1.5		 2y7hB-2vu5A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)		 2vu5 NUCLEOSIDE
DIPHOSPHATE KINASE
(Bacillus
anthracis) 		4 / 6 PHE A  57
PHE A  58
ALA A 123
THR A   4
 None
 1.12A 3t3sB-2vu5A:
undetectable		 3t3sB-2vu5A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2vu5 NUCLEOSIDE
DIPHOSPHATE KINASE
(Bacillus
anthracis) 		4 / 5 SER A 117
ALA A 123
HIS A 115
LEU A   6
 None
 1.46A 5dzkb-2vu5A:
undetectable
5dzkp-2vu5A:
undetectable		 5dzkb-2vu5A:
20.39
5dzkp-2vu5A:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2vu5 NUCLEOSIDE
DIPHOSPHATE KINASE
(Bacillus
anthracis) 		4 / 5 SER A 117
ALA A 123
HIS A 115
LEU A   6
 None
 1.43A 5dzkc-2vu5A:
undetectable
5dzkq-2vu5A:
undetectable		 5dzkc-2vu5A:
20.39
5dzkq-2vu5A:
6.25