SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vul'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 2vul GH11 XYLANASE
(Escherichia
coli) 		4 / 7 TYR A  91
TYR A  80
TYR A 175
TYR A  39
 None
None
12P  A1199 (-4.2A)
None
 1.31A 3ku9B-2vulA:
undetectable		 3ku9B-2vulA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2vul GH11 XYLANASE
(Escherichia
coli) 		3 / 3 GLY A  97
THR A  71
ASN A  74
 None
 0.68A 3v4tD-2vulA:
undetectable		 3v4tD-2vulA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 2vul GH11 XYLANASE
(Escherichia
coli) 		4 / 7 SER A 114
VAL A  92
TYR A 119
ARG A 145
 None
 1.10A 4ijiH-2vulA:
undetectable		 4ijiH-2vulA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ACL_A_SASA1111_1
(MCG)		 2vul GH11 XYLANASE
(Escherichia
coli) 		4 / 7 TYR A  76
TYR A  39
GLU A 181
PHE A  69
 None
 1.11A 5aclA-2vulA:
undetectable		 5aclA-2vulA:
20.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2vul GH11 XYLANASE
(Escherichia
coli) 		4 / 8 TYR A 122
ARG A 126
GLN A 140
TRP A 142
 None
 0.67A 5tzoA-2vulA:
28.5		 5tzoA-2vulA:
51.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2vul GH11 XYLANASE
(Escherichia
coli) 		7 / 12 VAL A  50
TRP A  82
TYR A  91
PRO A 130
TRP A 142
TYR A 175
GLY A 182
 None
12P  A1199 ( 4.7A)
None
12P  A1199 ( 4.6A)
None
12P  A1199 (-4.2A)
None
 0.82A 5tzoA-2vulA:
28.5		 5tzoA-2vulA:
51.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2vul GH11 XYLANASE
(Escherichia
coli) 		6 / 12 VAL A  50
TRP A  82
TYR A  91
TRP A 142
TYR A 175
GLY A 182
 None
12P  A1199 ( 4.7A)
None
None
12P  A1199 (-4.2A)
None
 0.76A 5tzoB-2vulA:
28.5		 5tzoB-2vulA:
51.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 2vul GH11 XYLANASE
(Escherichia
coli) 		3 / 3 ARG A 126
PRO A 130
TYR A 183
 None
12P  A1199 ( 4.6A)
None
 0.55A 5tzoB-2vulA:
28.5		 5tzoB-2vulA:
51.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2vul GH11 XYLANASE
(Escherichia
coli) 		4 / 8 TYR A 122
ARG A 126
GLN A 140
TRP A 142
 None
 0.49A 5tzoB-2vulA:
28.5		 5tzoB-2vulA:
51.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2vul GH11 XYLANASE
(Escherichia
coli) 		7 / 12 VAL A  50
TRP A  82
TYR A  91
PRO A 130
TRP A 142
TYR A 175
GLY A 182
 None
12P  A1199 ( 4.7A)
None
12P  A1199 ( 4.6A)
None
12P  A1199 (-4.2A)
None
 0.89A 5tzoC-2vulA:
28.4		 5tzoC-2vulA:
51.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2vul GH11 XYLANASE
(Escherichia
coli) 		4 / 8 TYR A 122
ARG A 126
GLN A 140
TRP A 142
 None
 0.61A 5tzoC-2vulA:
28.4		 5tzoC-2vulA:
51.44