SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vun'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 5 HIS A  67
HIS A 193
HIS A 220
ASP A 276
 ZN  A 401 (-3.3A)
FE  A 402 (-2.9A)
FE  A 402 (-3.1A)
ZN  A 401 (-2.9A)
 0.49A 1e9yB-2vunA:
20.9		 1e9yB-2vunA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		5 / 6 HIS A  67
HIS A  69
HIS A 193
HIS A 220
ASP A 276
 ZN  A 401 (-3.3A)
ZN  A 401 (-3.3A)
FE  A 402 (-2.9A)
FE  A 402 (-3.1A)
ZN  A 401 (-2.9A)
 0.65A 1fweC-2vunA:
21.8		 1fweC-2vunA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 8 ALA A 368
THR A   4
THR A  50
ILE A 385
 None
 0.75A 1gtnA-2vunA:
undetectable
1gtnB-2vunA:
undetectable		 1gtnA-2vunA:
12.90
1gtnB-2vunA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 7 THR A  66
VAL A 217
VAL A 247
ASP A 276
 None
None
None
ZN  A 401 (-2.9A)
 0.93A 1p7rA-2vunA:
undetectable		 1p7rA-2vunA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 8 ALA A 368
THR A   4
THR A  50
ILE A 385
 None
 0.80A 1utdB-2vunA:
undetectable
1utdC-2vunA:
undetectable		 1utdB-2vunA:
12.90
1utdC-2vunA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 8 ALA A 368
THR A   4
THR A  50
ILE A 385
 None
 0.80A 1utdF-2vunA:
undetectable
1utdG-2vunA:
undetectable		 1utdF-2vunA:
12.90
1utdG-2vunA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 8 ALA A 368
THR A   4
THR A  50
ILE A 385
 None
 0.77A 1utdI-2vunA:
undetectable
1utdJ-2vunA:
undetectable		 1utdI-2vunA:
12.90
1utdJ-2vunA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 8 ALA A 368
THR A   4
THR A  50
ILE A 385
 None
 0.79A 1utdJ-2vunA:
undetectable
1utdK-2vunA:
undetectable		 1utdJ-2vunA:
12.90
1utdK-2vunA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 8 GLU A 164
HIS A  69
ASP A 276
HIS A 220
 FE  A 402 ( 2.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-2.9A)
FE  A 402 (-3.1A)
 0.81A 1v7zA-2vunA:
undetectable		 1v7zA-2vunA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 8 GLU A 164
HIS A  69
ASP A 276
HIS A 220
 FE  A 402 ( 2.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-2.9A)
FE  A 402 (-3.1A)
 0.80A 1v7zB-2vunA:
undetectable		 1v7zB-2vunA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 8 GLU A 164
HIS A  69
ASP A 276
HIS A 220
 FE  A 402 ( 2.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-2.9A)
FE  A 402 (-3.1A)
 0.80A 1v7zC-2vunA:
undetectable		 1v7zC-2vunA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 8 GLU A 164
HIS A  69
ASP A 276
HIS A 220
 FE  A 402 ( 2.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-2.9A)
FE  A 402 (-3.1A)
 0.82A 1v7zD-2vunA:
undetectable		 1v7zD-2vunA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 8 GLU A 164
HIS A  69
ASP A 276
HIS A 220
 FE  A 402 ( 2.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-2.9A)
FE  A 402 (-3.1A)
 0.81A 1v7zE-2vunA:
undetectable		 1v7zE-2vunA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 8 GLU A 164
HIS A  69
ASP A 276
HIS A 220
 FE  A 402 ( 2.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-2.9A)
FE  A 402 (-3.1A)
 0.80A 1v7zF-2vunA:
undetectable		 1v7zF-2vunA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		3 / 3 ASP A 256
TYR A 257
GLU A 264
 None
 0.80A 1vm1A-2vunA:
undetectable		 1vm1A-2vunA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 5 PRO A 130
VAL A 135
VAL A  70
ILE A  85
 None
 1.11A 1z2bC-2vunA:
2.3		 1z2bC-2vunA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 5 GLY A  38
PRO A 327
ALA A 326
ILE A 325
 None
 0.86A 2aofA-2vunA:
undetectable		 2aofA-2vunA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 7 THR A  66
VAL A 217
VAL A 247
ASP A 276
 None
None
None
ZN  A 401 (-2.9A)
 1.01A 2cppA-2vunA:
undetectable		 2cppA-2vunA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_A_H4BA1003_1
(HYPOTHETICAL PROTEIN
PH0634)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		5 / 10 HIS A  67
HIS A 220
THR A  66
TYR A 318
ASP A 216
 ZN  A 401 (-3.3A)
FE  A 402 (-3.1A)
None
None
None
 1.25A 2dttA-2vunA:
undetectable
2dttC-2vunA:
undetectable		 2dttA-2vunA:
15.28
2dttC-2vunA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 5 VAL A 361
SER A  57
VAL A  59
SER A 360
 None
 1.39A 2j9cA-2vunA:
undetectable
2j9cB-2vunA:
undetectable
2j9cC-2vunA:
undetectable		 2j9cA-2vunA:
15.80
2j9cB-2vunA:
15.80
2j9cC-2vunA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 8 PRO A 130
SER A  98
SER A 101
ASP A  74
 None
None
GOL  A1390 (-3.2A)
None
 1.15A 2obvA-2vunA:
undetectable		 2obvA-2vunA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		5 / 10 THR A  66
VAL A 217
VAL A 218
VAL A 247
ASP A 276
 None
None
None
None
ZN  A 401 (-2.9A)
 1.11A 2qboA-2vunA:
undetectable		 2qboA-2vunA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		5 / 12 THR A 315
ASP A 332
GLU A 330
LEU A  64
HIS A 136
 None
 1.43A 2zj0A-2vunA:
undetectable		 2zj0A-2vunA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		5 / 12 THR A 315
ASP A 332
GLU A 330
LEU A  64
HIS A 136
 None
 1.50A 2zj0C-2vunA:
undetectable		 2zj0C-2vunA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 8 GLU A 164
HIS A  69
ASP A 276
HIS A 220
 FE  A 402 ( 2.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-2.9A)
FE  A 402 (-3.1A)
 0.81A 3a6jA-2vunA:
undetectable		 3a6jA-2vunA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 7 GLU A 164
HIS A  69
ASP A 276
HIS A 220
 FE  A 402 ( 2.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-2.9A)
FE  A 402 (-3.1A)
 0.78A 3a6jB-2vunA:
undetectable		 3a6jB-2vunA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 8 GLU A 164
HIS A  69
ASP A 276
HIS A 220
 FE  A 402 ( 2.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-2.9A)
FE  A 402 (-3.1A)
 0.78A 3a6jC-2vunA:
undetectable		 3a6jC-2vunA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 8 GLU A 164
HIS A  69
ASP A 276
HIS A 220
 FE  A 402 ( 2.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-2.9A)
FE  A 402 (-3.1A)
 0.80A 3a6jE-2vunA:
undetectable		 3a6jE-2vunA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 8 GLU A 164
HIS A  69
ASP A 276
HIS A 220
 FE  A 402 ( 2.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-2.9A)
FE  A 402 (-3.1A)
 0.78A 3a6jF-2vunA:
undetectable		 3a6jF-2vunA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		5 / 12 THR A 315
ASP A 332
GLU A 330
LEU A  64
HIS A 136
 None
 1.50A 3ce6B-2vunA:
2.2		 3ce6B-2vunA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		5 / 8 GLY A  47
ALA A  46
ASP A  45
THR A  26
ILE A   5
 None
 1.40A 3el0A-2vunA:
undetectable		 3el0A-2vunA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		5 / 12 ASN A 222
GLY A 250
VAL A 210
GLY A 195
ILE A 228
 None
 1.12A 3k13A-2vunA:
5.2		 3k13A-2vunA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		3 / 3 SER A 279
GLY A 280
THR A 281
 None
 0.17A 3k9wA-2vunA:
undetectable		 3k9wA-2vunA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		3 / 3 SER A 203
SER A 202
HIS A 193
 None
None
FE  A 402 (-2.9A)
 0.65A 3mzeA-2vunA:
undetectable		 3mzeA-2vunA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_I_SAMI228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		5 / 12 ALA A 352
ILE A 295
ASP A 256
ALA A 259
ASP A 302
 None
 1.06A 3nvkI-2vunA:
undetectable		 3nvkI-2vunA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 7 PHE A 188
ALA A 118
LEU A 146
LEU A 142
 None
GOL  A1390 ( 3.7A)
None
None
 0.93A 4ejgC-2vunA:
undetectable		 4ejgC-2vunA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 5 HIS A  67
HIS A 193
HIS A 220
ASP A 276
 ZN  A 401 (-3.3A)
FE  A 402 (-2.9A)
FE  A 402 (-3.1A)
ZN  A 401 (-2.9A)
 0.50A 4h9mA-2vunA:
22.7		 4h9mA-2vunA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 8 PRO A 130
SER A  98
SER A 101
ASP A  74
 None
None
GOL  A1390 (-3.2A)
None
 1.18A 4kttA-2vunA:
undetectable		 4kttA-2vunA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 8 PRO A 130
SER A  98
SER A 101
ASP A  74
 None
None
GOL  A1390 (-3.2A)
None
 1.18A 4ndnA-2vunA:
undetectable		 4ndnA-2vunA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		5 / 12 GLY A  92
ILE A 356
GLY A 358
ARG A 374
ASN A 375
 None
 1.05A 4obwC-2vunA:
undetectable		 4obwC-2vunA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		5 / 12 GLY A  92
ILE A 356
GLY A 358
ARG A 374
ASN A 375
 None
 1.03A 4obwD-2vunA:
undetectable		 4obwD-2vunA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		5 / 12 LEU A  63
GLY A  62
VAL A 361
ILE A  34
VAL A  29
 None
 1.24A 4okwA-2vunA:
undetectable		 4okwA-2vunA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		5 / 12 THR A 338
GLY A 349
ASP A 355
ASP A 346
SER A  57
 None
 1.39A 4pooB-2vunA:
undetectable		 4pooB-2vunA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 2vun ENAMIDASE
(Eubacterium
barkeri) 		5 / 6 HIS A  67
HIS A  69
HIS A 193
HIS A 220
ASP A 276
 ZN  A 401 (-3.3A)
ZN  A 401 (-3.3A)
FE  A 402 (-2.9A)
FE  A 402 (-3.1A)
ZN  A 401 (-2.9A)
 0.51A 4ubpC-2vunA:
21.0		 4ubpC-2vunA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		3 / 3 LYS A  80
ARG A  78
HIS A 103
 None
 1.12A 4zbrA-2vunA:
undetectable		 4zbrA-2vunA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 7 ILE A   9
GLY A  10
LEU A 289
ASP A 337
 None
 0.89A 5hieB-2vunA:
undetectable		 5hieB-2vunA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		5 / 12 ALA A  36
LEU A  42
MET A  43
LEU A 333
ILE A  37
 None
 1.12A 5m24A-2vunA:
undetectable		 5m24A-2vunA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_1
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 5 ARG A 290
ASP A  65
MET A  96
GLN A 191
 None
 1.44A 5ubbA-2vunA:
undetectable		 5ubbA-2vunA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_F_C2FF3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		5 / 12 ASN A 222
GLY A 250
VAL A 210
GLY A 195
ILE A 228
 None
 1.18A 5vooF-2vunA:
5.2		 5vooF-2vunA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		5 / 12 ASN A 222
GLY A 250
VAL A 210
GLY A 195
ILE A 228
 None
 1.11A 5vopB-2vunA:
5.3		 5vopB-2vunA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWP_A_FVXA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		5 / 9 ILE A 334
SER A  87
SER A 373
SER A 360
GLY A 358
 None
 1.43A 6awpA-2vunA:
undetectable		 6awpA-2vunA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BM5_A_SAMA1301_0
(METHIONINE SYNTHASE)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		5 / 11 PRO A 102
ARG A 107
PRO A 173
ALA A 176
PRO A 215
 None
GOL  A1390 (-4.1A)
None
None
None
 1.41A 6bm5A-2vunA:
undetectable		 6bm5A-2vunA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2vun ENAMIDASE
(Eubacterium
barkeri) 		4 / 8 PRO A 130
SER A  98
SER A 101
ASP A  74
 None
None
GOL  A1390 (-3.2A)
None
 1.12A 6fcbA-2vunA:
undetectable		 6fcbA-2vunA:
24.54