SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vuo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2vuo IG GAMMA CHAIN C
REGION
(Oryctolagus
cuniculus) 		4 / 7 SER A 378
LYS A 248
SER A 426
VAL A 379
 FMT  A1458 ( 2.6A)
FMT  A1458 (-2.8A)
FMT  A1458 (-2.7A)
GOL  A1454 (-4.5A)
 1.29A 2j9cA-2vuoA:
undetectable
2j9cB-2vuoA:
undetectable
2j9cC-2vuoA:
undetectable		 2j9cA-2vuoA:
22.28
2j9cB-2vuoA:
22.28
2j9cC-2vuoA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 2vuo IG GAMMA CHAIN C
REGION
(Oryctolagus
cuniculus) 		5 / 12 GLY A 352
PHE A 423
ILE A 441
ASP A 421
VAL A 363
 None
 1.12A 3o7wA-2vuoA:
undetectable		 3o7wA-2vuoA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 2vuo IG GAMMA CHAIN C
REGION
(Oryctolagus
cuniculus) 		4 / 4 LEU A 432
ILE A 377
HIS A 429
VAL A 427
 None
GOL  A1454 (-4.6A)
None
None
 1.33A 4xyzA-2vuoA:
undetectable		 4xyzA-2vuoA:
14.16