SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vvd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 2vvd SPIKE PROTEIN P1
(Pseudoalteromona
s
virus
PM2) 		4 / 5 ASP A 225
VAL A 224
SER A 221
ASP A 307
 None
 1.31A 1n2xB-2vvdA:
undetectable		 1n2xB-2vvdA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 2vvd SPIKE PROTEIN P1
(Pseudoalteromona
s
virus
PM2) 		3 / 3 PRO A 237
PHE A 239
ALA A 215
 None
 0.45A 3itaD-2vvdA:
undetectable		 3itaD-2vvdA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 2vvd SPIKE PROTEIN P1
(Pseudoalteromona
s
virus
PM2) 		4 / 6 PRO A 237
TYR A 175
VAL A 316
THR A 311
 None
 1.11A 3tneA-2vvdA:
undetectable		 3tneA-2vvdA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_C_QI9C602_0
(CYTOCHROME P450 2D6)		 2vvd SPIKE PROTEIN P1
(Pseudoalteromona
s
virus
PM2) 		5 / 9 PHE A 211
LEU A 206
ASP A 320
SER A 318
VAL A 286
 None
 1.39A 4wnvC-2vvdA:
undetectable		 4wnvC-2vvdA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 2vvd SPIKE PROTEIN P1
(Pseudoalteromona
s
virus
PM2) 		4 / 6 SER A 309
ASP A 270
ARG A 216
GLU A 315
 None
 1.07A 5cdqA-2vvdA:
undetectable
5cdqC-2vvdA:
undetectable
5cdqD-2vvdA:
undetectable		 5cdqA-2vvdA:
18.24
5cdqC-2vvdA:
18.24
5cdqD-2vvdA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 2vvd SPIKE PROTEIN P1
(Pseudoalteromona
s
virus
PM2) 		4 / 5 VAL A 301
VAL A 224
GLY A 223
PHE A 310
 None
 1.05A 5d4nA-2vvdA:
undetectable
5d4nC-2vvdA:
undetectable		 5d4nA-2vvdA:
18.78
5d4nC-2vvdA:
18.78