SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vve'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 2vve SPIKE PROTEIN P1
(Pseudoalteromona
s
virus
PM2) 		4 / 5 ASP A 224
VAL A 223
SER A 220
ASP A 306
 None
 1.26A 1n2xB-2vveA:
undetectable		 1n2xB-2vveA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 2vve SPIKE PROTEIN P1
(Pseudoalteromona
s
virus
PM2) 		4 / 6 SER A 220
SER A 261
ASP A 228
GLU A 299
 None
 1.17A 2j2pE-2vveA:
undetectable
2j2pF-2vveA:
undetectable		 2j2pE-2vveA:
23.02
2j2pF-2vveA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_B_VDYB6178_1
(VITAMIN D
HYDROXYLASE)		 2vve SPIKE PROTEIN P1
(Pseudoalteromona
s
virus
PM2) 		5 / 12 ASN A  94
MET A 332
ILE A 119
VAL A 163
LEU A 100
 None
 1.41A 3a51B-2vveA:
undetectable		 3a51B-2vveA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 2vve SPIKE PROTEIN P1
(Pseudoalteromona
s
virus
PM2) 		3 / 3 PRO A 236
PHE A 238
ALA A 214
 None
 0.50A 3itaD-2vveA:
undetectable		 3itaD-2vveA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 2vve SPIKE PROTEIN P1
(Pseudoalteromona
s
virus
PM2) 		4 / 6 PRO A 236
TYR A 174
VAL A 315
THR A 310
 None
 1.12A 3tneA-2vveA:
undetectable		 3tneA-2vveA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_C_QI9C602_0
(CYTOCHROME P450 2D6)		 2vve SPIKE PROTEIN P1
(Pseudoalteromona
s
virus
PM2) 		5 / 9 PHE A 210
LEU A 205
ASP A 319
SER A 317
VAL A 285
 None
 1.32A 4wnvC-2vveA:
undetectable		 4wnvC-2vveA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 2vve SPIKE PROTEIN P1
(Pseudoalteromona
s
virus
PM2) 		4 / 5 GLY A 227
SER A 261
GLU A 299
ASP A 228
 None
 1.37A 4xueA-2vveA:
undetectable		 4xueA-2vveA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 2vve SPIKE PROTEIN P1
(Pseudoalteromona
s
virus
PM2) 		4 / 5 VAL A 300
VAL A 223
GLY A 222
PHE A 309
 None
 1.06A 5d4nA-2vveA:
undetectable
5d4nC-2vveA:
undetectable		 5d4nA-2vveA:
15.35
5d4nC-2vveA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 2vve SPIKE PROTEIN P1
(Pseudoalteromona
s
virus
PM2) 		3 / 3 TRP A 126
ILE A 125
ASP A 124
 None
 0.90A 6i0y7-2vveA:
undetectable		 6i0y7-2vveA:
9.62