SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vvr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1N49_B_RITB301_1 (PROTEASE)	2vvr	RIBOSE-5-PHOSPHATE ISOMERASE B (Escherichia coli)	4 / 7	ASP A 42 GLY A 71 ILE A 74 ALA A 51	None	0.63A	1n49A-2vvrA: undetectable	1n49A-2vvrA: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXE_B_1FLB2003_1 (SERUM ALBUMIN)	2vvr	RIBOSE-5-PHOSPHATE ISOMERASE B (Escherichia coli)	5 / 10	LEU A 105 PHE A 107 ARG A 26 LEU A 23 ILE A 19	None	0.96A	2bxeB-2vvrA: undetectable	2bxeB-2vvrA: 14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LB0_A_ACTA401_0 (UNCHARACTERIZED PROTEIN)	2vvr	RIBOSE-5-PHOSPHATE ISOMERASE B (Escherichia coli)	5 / 9	GLY A 108 SER A 109 ASP A 9 CYH A 66 GLY A 69	None	1.28A	4lb0A-2vvrA: undetectable	4lb0A-2vvrA: 18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N5D_B_SAMB303_0 (METHYLTRANSFERASE)	2vvr	RIBOSE-5-PHOSPHATE ISOMERASE B (Escherichia coli)	5 / 12	LEU A 52 ALA A 55 VAL A 54 ILE A 74 ALA A 47	None	1.06A	5n5dB-2vvrA: undetectable	5n5dB-2vvrA: 21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EBP_B_DAHB123_0 (RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE, BETA SUBUNIT)	2vvr	RIBOSE-5-PHOSPHATE ISOMERASE B (Escherichia coli)	5 / 10	LEU A 114 SER A 109 GLY A 108 ILE A 65 PHE A 107	None	1.22A	6ebpB-2vvrA: undetectable	6ebpB-2vvrA: 18.12

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1N49_B_RITB301_1","PROTEASE;PROTEASE","2vvr","RIBOSE-5-PHOSPHATE ISOMERASE B","Escherichia coli",4,"ASP A  42;GLY A  71;ILE A  74;ALA A  51","None","0.63A","1n49A-2vvrA:undetectable","1n49A-2vvrA:18.18"],["2BXE_B_1FLB2003_1","SERUM ALBUMIN","2vvr","RIBOSE-5-PHOSPHATE ISOMERASE B","Escherichia coli",5,"LEU A 105;PHE A 107;ARG A  26;LEU A  23;ILE A  19","None","0.96A","2bxeB-2vvrA:undetectable","2bxeB-2vvrA:14.94"],["4LB0_A_ACTA401_0","UNCHARACTERIZED PROTEIN","2vvr","RIBOSE-5-PHOSPHATE ISOMERASE B","Escherichia coli",5,"GLY A 108;SER A 109;ASP A   9;CYH A  66;GLY A  69","None","1.28A","4lb0A-2vvrA:undetectable","4lb0A-2vvrA:18.29"],["5N5D_B_SAMB303_0","METHYLTRANSFERASE","2vvr","RIBOSE-5-PHOSPHATE ISOMERASE B","Escherichia coli",5,"LEU A  52;ALA A  55;VAL A  54;ILE A  74;ALA A  47","None","1.06A","5n5dB-2vvrA:undetectable","5n5dB-2vvrA:21.05"],["6EBP_B_DAHB123_0","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE, BETA SUBUNIT","2vvr","RIBOSE-5-PHOSPHATE ISOMERASE B","Escherichia coli",5,"LEU A 114;SER A 109;GLY A 108;ILE A  65;PHE A 107","None","1.22A","6ebpB-2vvrA:undetectable","6ebpB-2vvrA:18.12"]]