SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vvt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		3 / 3 TRP A  56
ALA A  77
VAL A  52
 None
 0.87A 1c4dA-2vvtA:
undetectable
1c4dB-2vvtA:
undetectable		 1c4dA-2vvtA:
4.67
1c4dB-2vvtA:
4.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		3 / 3 ALA A  77
VAL A  52
TRP A  56
 None
 0.94A 1c4dC-2vvtA:
undetectable
1c4dD-2vvtA:
undetectable		 1c4dC-2vvtA:
4.67
1c4dD-2vvtA:
4.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		3 / 3 TRP A  56
ALA A  77
VAL A  52
 None
 0.87A 1c4dC-2vvtA:
undetectable
1c4dD-2vvtA:
undetectable		 1c4dC-2vvtA:
4.67
1c4dD-2vvtA:
4.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
None
DGL  A1270 (-3.0A)
 1.02A 1c9sP-2vvtA:
undetectable
1c9sQ-2vvtA:
undetectable		 1c9sP-2vvtA:
12.76
1c9sQ-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_2
(PROTEIN (HIV-1
PROTEASE))		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		4 / 8 LEU A  89
ILE A  33
VAL A  93
ILE A  91
 None
 0.59A 1d4yB-2vvtA:
undetectable		 1d4yB-2vvtA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 9 GLY A 184
THR A 186
ALA A  77
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
None
None
DGL  A1270 (-3.6A)
 0.91A 1gtfD-2vvtA:
undetectable
1gtfE-2vvtA:
undetectable		 1gtfD-2vvtA:
12.76
1gtfE-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
ALA A  77
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
None
None
DGL  A1270 (-3.6A)
 0.98A 1gtfJ-2vvtA:
undetectable
1gtfK-2vvtA:
undetectable		 1gtfJ-2vvtA:
12.76
1gtfK-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.11A 1gtfJ-2vvtA:
undetectable
1gtfK-2vvtA:
undetectable		 1gtfJ-2vvtA:
12.76
1gtfK-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
None
DGL  A1270 (-3.0A)
 1.02A 1gtfQ-2vvtA:
undetectable
1gtfR-2vvtA:
undetectable		 1gtfQ-2vvtA:
12.76
1gtfR-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
None
DGL  A1270 (-3.0A)
 1.03A 1gtfS-2vvtA:
undetectable
1gtfT-2vvtA:
undetectable		 1gtfS-2vvtA:
12.76
1gtfT-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
None
DGL  A1270 (-3.0A)
 1.05A 1gtnT-2vvtA:
undetectable
1gtnU-2vvtA:
undetectable		 1gtnT-2vvtA:
12.76
1gtnU-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		4 / 7 TYR A 188
VAL A  96
ILE A  97
LEU A 181
 None
 1.01A 1j96B-2vvtA:
undetectable		 1j96B-2vvtA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 ILE A 138
ASP A 179
LYS A 106
ILE A 182
ILE A 131
 None
 1.24A 1rb3A-2vvtA:
undetectable		 1rb3A-2vvtA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
None
DGL  A1270 (-3.0A)
 1.07A 1utdE-2vvtA:
undetectable
1utdF-2vvtA:
undetectable		 1utdE-2vvtA:
12.76
1utdF-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 ALA A  77
THR A 121
THR A 118
GLY A 184
THR A 186
 None
None
DGL  A1270 (-3.6A)
None
DGL  A1270 (-3.0A)
 0.96A 1utdH-2vvtA:
undetectable
1utdI-2vvtA:
undetectable		 1utdH-2vvtA:
12.76
1utdI-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
None
DGL  A1270 (-3.0A)
 1.07A 1utdH-2vvtA:
undetectable
1utdI-2vvtA:
undetectable		 1utdH-2vvtA:
12.76
1utdI-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 12 ALA A  77
THR A 121
THR A 118
GLY A 184
THR A 186
 None
None
DGL  A1270 (-3.6A)
None
DGL  A1270 (-3.0A)
 0.98A 1utdL-2vvtA:
undetectable
1utdM-2vvtA:
undetectable		 1utdL-2vvtA:
12.76
1utdM-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 11 ALA A  77
THR A 121
THR A 118
GLY A 184
THR A 186
 None
None
DGL  A1270 (-3.6A)
None
DGL  A1270 (-3.0A)
 0.96A 1utdP-2vvtA:
undetectable
1utdQ-2vvtA:
undetectable		 1utdP-2vvtA:
12.76
1utdQ-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
None
DGL  A1270 (-3.0A)
 1.04A 1utdS-2vvtA:
undetectable
1utdT-2vvtA:
undetectable		 1utdS-2vvtA:
12.76
1utdT-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 11 GLY A 184
THR A 186
ALA A  77
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
None
None
DGL  A1270 (-3.6A)
 0.98A 1utdL-2vvtA:
undetectable
1utdV-2vvtA:
undetectable		 1utdL-2vvtA:
12.76
1utdV-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 11 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.06A 1utdL-2vvtA:
undetectable
1utdV-2vvtA:
undetectable		 1utdL-2vvtA:
12.76
1utdV-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		3 / 3 VAL A  94
VAL A 213
ASP A 224
 None
 0.77A 2fumD-2vvtA:
undetectable		 2fumD-2vvtA:
28.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		4 / 8 GLU A  30
LEU A 220
VAL A  71
ALA A   6
 None
 1.01A 3ax9A-2vvtA:
undetectable		 3ax9A-2vvtA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_2
(DIHYDROFOLATE
REDUCTASE)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		4 / 5 ARG A 102
ILE A  97
VAL A 115
THR A 108
 None
 1.14A 3eigA-2vvtA:
3.1		 3eigA-2vvtA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 12 ALA A  73
GLU A 215
VAL A  94
GLY A  95
VAL A  19
 None
 0.98A 3f8wA-2vvtA:
undetectable		 3f8wA-2vvtA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 12 ALA A  73
GLU A 215
VAL A  94
GLY A  95
VAL A  19
 None
 0.98A 3f8wC-2vvtA:
undetectable		 3f8wC-2vvtA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		4 / 7 ALA A 251
PHE A 247
ALA A 262
LEU A 260
 None
 0.95A 4du2A-2vvtA:
undetectable		 4du2A-2vvtA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_B_CLQB303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 11 HIS A 236
PHE A 238
PHE A 247
GLY A  16
GLY A  15
 None
None
None
None
I24  A1269 ( 3.8A)
 1.35A 4fglA-2vvtA:
undetectable
4fglB-2vvtA:
undetectable		 4fglA-2vvtA:
20.45
4fglB-2vvtA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		3 / 3 GLN A 264
THR A 241
THR A 240
 None
 0.82A 4fu9A-2vvtA:
undetectable		 4fu9A-2vvtA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		3 / 3 GLN A 264
THR A 241
THR A 240
 None
 0.79A 4fufA-2vvtA:
undetectable		 4fufA-2vvtA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		4 / 5 GLY A  15
ASP A  11
GLU A  22
VAL A 216
 I24  A1269 ( 3.8A)
DGL  A1270 (-3.4A)
None
None
 0.95A 4nkvD-2vvtA:
undetectable		 4nkvD-2vvtA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		3 / 3 MET A   1
ASP A 224
PHE A 223
 None
 1.05A 4xeyA-2vvtA:
undetectable		 4xeyA-2vvtA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		3 / 3 MET A   1
ASP A 224
PHE A 223
 None
 1.00A 4xeyB-2vvtA:
undetectable		 4xeyB-2vvtA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 12 LEU A 143
VAL A 198
VAL A 194
LEU A 191
MET A 199
 None
 0.98A 4y0qA-2vvtA:
undetectable		 4y0qA-2vvtA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.10A 5eevA-2vvtA:
undetectable
5eevB-2vvtA:
undetectable		 5eevA-2vvtA:
12.76
5eevB-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.10A 5eewA-2vvtA:
undetectable
5eewB-2vvtA:
undetectable		 5eewA-2vvtA:
12.76
5eewB-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.10A 5eexA-2vvtA:
undetectable
5eexB-2vvtA:
undetectable		 5eexA-2vvtA:
12.76
5eexB-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.10A 5eeyA-2vvtA:
undetectable
5eeyB-2vvtA:
undetectable		 5eeyA-2vvtA:
12.76
5eeyB-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.10A 5eezA-2vvtA:
undetectable
5eezB-2vvtA:
undetectable		 5eezA-2vvtA:
12.76
5eezB-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.10A 5ef0A-2vvtA:
undetectable
5ef0B-2vvtA:
undetectable		 5ef0A-2vvtA:
12.76
5ef0B-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.10A 5ef1A-2vvtA:
undetectable
5ef1B-2vvtA:
undetectable		 5ef1A-2vvtA:
12.76
5ef1B-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.10A 5ef2A-2vvtA:
undetectable
5ef2B-2vvtA:
undetectable		 5ef2A-2vvtA:
12.76
5ef2B-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.10A 5ef3A-2vvtA:
undetectable
5ef3B-2vvtA:
undetectable		 5ef3A-2vvtA:
12.76
5ef3B-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		4 / 7 LEU A 260
THR A 240
THR A 241
LEU A 255
 None
 0.78A 5jq7B-2vvtA:
undetectable		 5jq7B-2vvtA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		4 / 7 TYR A 127
THR A 121
THR A  76
LEU A 181
 None
None
DGL  A1270 (-3.8A)
None
 1.13A 5jq7B-2vvtA:
undetectable		 5jq7B-2vvtA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		4 / 8 ALA A   6
VAL A  96
TYR A  34
HIS A 236
 None
 0.96A 5nu7A-2vvtA:
undetectable		 5nu7A-2vvtA:
19.86