SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vvy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 2vvy PROTEIN B15
(Vaccinia
virus) 		5 / 10 THR A 122
ALA A 112
ASN A 127
ALA A 128
ILE A  34
 None
 1.08A 1likA-2vvyA:
undetectable		 1likA-2vvyA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		4 / 8 CYH A  29
TYR A  51
LEU A  20
MET A 148
 None
 1.08A 1uw6A-2vvyA:
undetectable
1uw6B-2vvyA:
undetectable		 1uw6A-2vvyA:
20.66
1uw6B-2vvyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_B_NCTB1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		5 / 9 TYR A  33
CYH A  29
TYR A  51
LEU A  20
MET A 148
 None
 1.12A 1uw6B-2vvyA:
undetectable
1uw6C-2vvyA:
undetectable		 1uw6B-2vvyA:
20.66
1uw6C-2vvyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		4 / 8 CYH A  29
TYR A  51
LEU A  20
MET A 148
 None
 1.09A 1uw6D-2vvyA:
undetectable
1uw6E-2vvyA:
undetectable		 1uw6D-2vvyA:
20.66
1uw6E-2vvyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_F_NCTF1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		5 / 10 TYR A  33
CYH A  29
TYR A  51
LEU A  20
MET A 148
 None
 1.07A 1uw6F-2vvyA:
undetectable
1uw6G-2vvyA:
undetectable		 1uw6F-2vvyA:
20.66
1uw6G-2vvyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_F_NCTF1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		5 / 10 TYR A  33
CYH A  29
TYR A  51
LEU A  20
MET A 148
 None
 1.16A 1uw6F-2vvyA:
undetectable
1uw6G-2vvyA:
undetectable		 1uw6F-2vvyA:
20.66
1uw6G-2vvyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		4 / 8 CYH A  29
TYR A  51
LEU A  20
MET A 148
 None
 1.07A 1uw6G-2vvyA:
undetectable
1uw6H-2vvyA:
undetectable		 1uw6G-2vvyA:
20.66
1uw6H-2vvyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_H_NCTH1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		5 / 10 TYR A  33
CYH A  29
TYR A  51
LEU A  20
MET A 148
 None
 1.08A 1uw6H-2vvyA:
undetectable
1uw6I-2vvyA:
undetectable		 1uw6H-2vvyA:
20.66
1uw6I-2vvyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_H_NCTH1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		5 / 10 TYR A  33
CYH A  29
TYR A  51
LEU A  20
MET A 148
 None
 1.15A 1uw6H-2vvyA:
undetectable
1uw6I-2vvyA:
undetectable		 1uw6H-2vvyA:
20.66
1uw6I-2vvyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_J_NCTJ1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		5 / 9 LEU A  20
MET A 148
TYR A  33
CYH A  29
TYR A  51
 None
 1.05A 1uw6F-2vvyA:
undetectable
1uw6J-2vvyA:
undetectable		 1uw6F-2vvyA:
20.66
1uw6J-2vvyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_M_NCTM1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		5 / 10 TYR A  33
CYH A  29
TYR A  51
LEU A  20
MET A 148
 None
 1.10A 1uw6M-2vvyA:
undetectable
1uw6N-2vvyA:
undetectable		 1uw6M-2vvyA:
20.66
1uw6N-2vvyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_M_NCTM1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		5 / 10 TYR A  33
CYH A  29
TYR A  51
LEU A  20
MET A 148
 None
 1.19A 1uw6M-2vvyA:
undetectable
1uw6N-2vvyA:
undetectable		 1uw6M-2vvyA:
20.66
1uw6N-2vvyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_N_NCTN1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		5 / 10 TYR A  33
CYH A  29
TYR A  51
LEU A  20
MET A 148
 None
 1.11A 1uw6N-2vvyA:
undetectable
1uw6O-2vvyA:
undetectable		 1uw6N-2vvyA:
20.66
1uw6O-2vvyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_N_NCTN1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		5 / 10 TYR A  33
CYH A  29
TYR A  51
LEU A  20
MET A 148
 None
 1.16A 1uw6N-2vvyA:
undetectable
1uw6O-2vvyA:
undetectable		 1uw6N-2vvyA:
20.66
1uw6O-2vvyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_O_NCTO1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		5 / 9 LEU A  20
MET A 148
TYR A  33
CYH A  29
TYR A  51
 None
 1.07A 1uw6K-2vvyA:
undetectable
1uw6O-2vvyA:
undetectable		 1uw6K-2vvyA:
20.66
1uw6O-2vvyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		4 / 8 CYH A  29
TYR A  51
LEU A  20
MET A 148
 None
 1.09A 1uw6P-2vvyA:
undetectable
1uw6Q-2vvyA:
undetectable		 1uw6P-2vvyA:
20.66
1uw6Q-2vvyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_Q_NCTQ1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		5 / 10 TYR A  33
CYH A  29
TYR A  51
LEU A  20
MET A 148
 None
 1.09A 1uw6Q-2vvyA:
undetectable
1uw6R-2vvyA:
undetectable		 1uw6Q-2vvyA:
20.66
1uw6R-2vvyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_Q_NCTQ1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		5 / 10 TYR A  33
CYH A  29
TYR A  51
LEU A  20
MET A 148
 None
 1.17A 1uw6Q-2vvyA:
undetectable
1uw6R-2vvyA:
undetectable		 1uw6Q-2vvyA:
20.66
1uw6R-2vvyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_S_NCTS1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		5 / 10 TYR A  33
CYH A  29
TYR A  51
LEU A  20
MET A 148
 None
 1.08A 1uw6S-2vvyA:
undetectable
1uw6T-2vvyA:
undetectable		 1uw6S-2vvyA:
20.66
1uw6T-2vvyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_S_NCTS1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		5 / 10 TYR A  33
CYH A  29
TYR A  51
LEU A  20
MET A 148
 None
 1.17A 1uw6S-2vvyA:
undetectable
1uw6T-2vvyA:
undetectable		 1uw6S-2vvyA:
20.66
1uw6T-2vvyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		4 / 8 LEU A  20
MET A 148
CYH A  29
TYR A  51
 None
 1.16A 1uw6P-2vvyA:
undetectable
1uw6T-2vvyA:
undetectable		 1uw6P-2vvyA:
20.66
1uw6T-2vvyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 2vvy PROTEIN B15
(Vaccinia
virus) 		3 / 3 ARG A 146
ASP A  24
ASN A 142
 None
 0.88A 2zzmA-2vvyA:
undetectable		 2zzmA-2vvyA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		4 / 8 TYR A  33
TYR A  51
LEU A  20
MET A 148
 None
 1.17A 3wipG-2vvyA:
undetectable
3wipH-2vvyA:
undetectable		 3wipG-2vvyA:
18.18
3wipH-2vvyA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_H_ACHH301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		5 / 9 TYR A  33
CYH A  29
TYR A  51
LEU A  20
MET A 148
 None
 1.17A 3wipH-2vvyA:
undetectable
3wipI-2vvyA:
undetectable		 3wipH-2vvyA:
18.18
3wipI-2vvyA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vvy PROTEIN B15
(Vaccinia
virus) 		4 / 8 LEU A  20
MET A 148
TYR A  33
TYR A  51
 None
 1.28A 3wipF-2vvyA:
undetectable
3wipJ-2vvyA:
undetectable		 3wipF-2vvyA:
18.18
3wipJ-2vvyA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2vvy PROTEIN B15
(Vaccinia
virus) 		4 / 8 LEU A  20
THR A  53
LEU A  54
LEU A  50
 None
 0.74A 4z90F-2vvyA:
undetectable
4z90G-2vvyA:
2.1
4z90H-2vvyA:
2.1
4z90I-2vvyA:
undetectable
4z90J-2vvyA:
undetectable		 4z90F-2vvyA:
20.34
4z90G-2vvyA:
20.34
4z90H-2vvyA:
20.34
4z90I-2vvyA:
20.34
4z90J-2vvyA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)		 2vvy PROTEIN B15
(Vaccinia
virus) 		4 / 8 HIS A  14
GLN A  28
LEU A  50
LEU A  20
 None
 1.17A 5hs6A-2vvyA:
undetectable		 5hs6A-2vvyA:
18.18