SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vxb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 2vxb DNA REPAIR PROTEIN
RHP9
(Schizosaccharomy
ces
pombe) 		4 / 7 LEU A 158
SER A 157
ASP A 160
PHE A  61
 None
 1.05A 1ismB-2vxbA:
undetectable		 1ismB-2vxbA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_B_TACB1888_1
(ELONGATION FACTOR
EF-TU)		 2vxb DNA REPAIR PROTEIN
RHP9
(Schizosaccharomy
ces
pombe) 		4 / 5 THR A 258
SER A 254
ASP A 255
SER A 252
 None
 1.28A 2hdnA-2vxbA:
undetectable
2hdnB-2vxbA:
undetectable
2hdnD-2vxbA:
undetectable		 2hdnA-2vxbA:
9.64
2hdnB-2vxbA:
21.15
2hdnD-2vxbA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_D_TACD2888_1
(ELONGATION FACTOR
EF-TU)		 2vxb DNA REPAIR PROTEIN
RHP9
(Schizosaccharomy
ces
pombe) 		4 / 5 SER A 252
THR A 258
SER A 254
ASP A 255
 None
 1.33A 2hdnB-2vxbA:
undetectable
2hdnC-2vxbA:
undetectable
2hdnD-2vxbA:
undetectable		 2hdnB-2vxbA:
21.15
2hdnC-2vxbA:
9.64
2hdnD-2vxbA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 2vxb DNA REPAIR PROTEIN
RHP9
(Schizosaccharomy
ces
pombe) 		4 / 6 THR A 258
SER A 254
ASP A 255
SER A 252
 None
 1.29A 2hdnI-2vxbA:
undetectable
2hdnJ-2vxbA:
undetectable
2hdnL-2vxbA:
undetectable		 2hdnI-2vxbA:
9.64
2hdnJ-2vxbA:
21.15
2hdnL-2vxbA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 2vxb DNA REPAIR PROTEIN
RHP9
(Schizosaccharomy
ces
pombe) 		4 / 5 ASN A  85
LEU A 158
SER A  83
LEU A  51
 None
 1.31A 4n09C-2vxbA:
undetectable		 4n09C-2vxbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2vxb DNA REPAIR PROTEIN
RHP9
(Schizosaccharomy
ces
pombe) 		4 / 5 ALA A 199
TYR A 202
GLY A  50
LEU A  60
 None
 0.95A 5eslA-2vxbA:
undetectable		 5eslA-2vxbA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 2vxb DNA REPAIR PROTEIN
RHP9
(Schizosaccharomy
ces
pombe) 		4 / 4 ASN A  85
LEU A 158
SER A  83
LEU A  51
 None
 1.28A 5kb5A-2vxbA:
undetectable		 5kb5A-2vxbA:
23.81