SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vxg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 2vxg CG6181-PA, ISOFORM A
(Drosophila
melanogaster) 		5 / 9 ILE A1222
LEU A1289
VAL A1247
GLY A1245
ALA A1238
 None
 1.13A 1e7aA-2vxgA:
undetectable		 1e7aA-2vxgA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)		 2vxg CG6181-PA, ISOFORM A
(Drosophila
melanogaster) 		5 / 9 ILE A1222
LEU A1289
VAL A1247
GLY A1245
ALA A1238
 None
 1.18A 1e7bA-2vxgA:
undetectable		 1e7bA-2vxgA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_F_REAF177_1
(RETINOL BINDING
PROTEIN)		 2vxg CG6181-PA, ISOFORM A
(Drosophila
melanogaster) 		5 / 11 LEU A1244
VAL A1247
LEU A1239
LEU A1275
GLN A1277
 None
 1.17A 1rlbF-2vxgA:
undetectable		 1rlbF-2vxgA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2vxg CG6181-PA, ISOFORM A
(Drosophila
melanogaster) 		4 / 4 ASN A1232
ILE A1279
TYR A1293
PHE A1249
 None
 1.13A 5igvA-2vxgA:
undetectable		 5igvA-2vxgA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNA_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 2vxg CG6181-PA, ISOFORM A
(Drosophila
melanogaster) 		3 / 3 ARG A1340
LYS A1344
TYR A1320
 None
 0.91A 6gnaA-2vxgA:
undetectable		 6gnaA-2vxgA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNB_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 2vxg CG6181-PA, ISOFORM A
(Drosophila
melanogaster) 		3 / 3 ARG A1340
LYS A1344
TYR A1320
 None
 0.91A 6gnbA-2vxgA:
undetectable		 6gnbA-2vxgA:
19.38