SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vxk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 2vxk GLUCOSAMINE
6-PHOSPHATE
ACETYLTRANSFERASE
(Aspergillus
fumigatus) 		3 / 3 ASP A  57
LEU A  97
LEU A  53
 None
 0.64A 1ikeA-2vxkA:
undetectable		 1ikeA-2vxkA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 2vxk GLUCOSAMINE
6-PHOSPHATE
ACETYLTRANSFERASE
(Aspergillus
fumigatus) 		3 / 3 ASP A  57
LEU A  97
LEU A  53
 None
 0.65A 1np1B-2vxkA:
undetectable		 1np1B-2vxkA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2vxk GLUCOSAMINE
6-PHOSPHATE
ACETYLTRANSFERASE
(Aspergillus
fumigatus) 		4 / 6 ILE A 147
ILE A 106
TYR A  62
LEU A 164
 None
None
None
16G  A1191 ( 3.9A)
 1.04A 3adsA-2vxkA:
undetectable		 3adsA-2vxkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 2vxk GLUCOSAMINE
6-PHOSPHATE
ACETYLTRANSFERASE
(Aspergillus
fumigatus) 		3 / 3 ILE A 106
VAL A  98
ARG A  51
 None
 0.71A 3p73A-2vxkA:
undetectable		 3p73A-2vxkA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EDL_A_VIBA201_1
(PUTATIVE
HMP/THIAMINE
PERMEASE PROTEIN
YKOE)		 2vxk GLUCOSAMINE
6-PHOSPHATE
ACETYLTRANSFERASE
(Aspergillus
fumigatus) 		5 / 12 TYR A  62
TRP A  80
GLU A  85
ILE A  87
SER A 111
 None
 1.39A 5edlA-2vxkA:
undetectable		 5edlA-2vxkA:
25.47