SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vxz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_D_DESD128_1
(TRANSTHYRETIN)		 2vxz PYRSV_GP04
(Pyrobaculum
spherical
virus) 		4 / 4 LYS A  25
LEU A  20
LEU A  67
SER A  68
 None
 1.50A 1tz8D-2vxzA:
undetectable		 1tz8D-2vxzA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 2vxz PYRSV_GP04
(Pyrobaculum
spherical
virus) 		5 / 11 ASP A 107
ARG A  85
ILE A 120
ILE A 104
ILE A 105
 None
 1.26A 5hw8B-2vxzA:
undetectable		 5hw8B-2vxzA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 2vxz PYRSV_GP04
(Pyrobaculum
spherical
virus) 		3 / 3 LEU A 131
SER A 129
PHE A 130
 None
 0.65A 6fgcA-2vxzA:
undetectable		 6fgcA-2vxzA:
17.66