SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vy0'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTI_C_CCSC47_0 (GLUTATHIONE S-TRANSFERASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	LEU A  84 GLY A 148 LYS A 105 TYR A 118	None	1.25A	1gtiC-2vy0A: undetectable	1gtiC-2vy0A: 20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTI_F_CCSF47_0 (GLUTATHIONE S-TRANSFERASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 5	LEU A  84 GLY A 148 LYS A 105 TYR A 118	None	1.25A	1gtiF-2vy0A: undetectable	1gtiF-2vy0A: 20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1J96_B_TESB904_1 (3ALPHA-HYDROXYSTEROI D DEHYDROGENASE TYPE 3)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 240 ILE A 228 GLU A 175 LEU A 156	None None MPD  A1299 (-3.4A) None	1.04A	1j96B-2vy0A: undetectable	1j96B-2vy0A: 20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1K2R_A_H4BA1760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.41A	1k2rA-2vy0A: undetectable 1k2rB-2vy0A: undetectable	1k2rA-2vy0A: 19.68 1k2rB-2vy0A: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1K2R_B_H4BB2760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.39A	1k2rA-2vy0A: undetectable 1k2rB-2vy0A: undetectable	1k2rA-2vy0A: 19.68 1k2rB-2vy0A: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1K2S_A_H4BA1760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.38A	1k2sA-2vy0A: undetectable 1k2sB-2vy0A: undetectable	1k2sA-2vy0A: 19.68 1k2sB-2vy0A: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1K2T_A_H4BA1760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	1k2tA-2vy0A: undetectable 1k2tB-2vy0A: undetectable	1k2tA-2vy0A: 19.68 1k2tB-2vy0A: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1K2T_B_H4BB2760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	1k2tA-2vy0A: undetectable 1k2tB-2vy0A: undetectable	1k2tA-2vy0A: 19.68 1k2tB-2vy0A: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1K2U_A_H4BA1760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.41A	1k2uA-2vy0A: undetectable 1k2uB-2vy0A: undetectable	1k2uA-2vy0A: 19.68 1k2uB-2vy0A: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1K2U_B_H4BB2760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	1k2uA-2vy0A: undetectable 1k2uB-2vy0A: undetectable	1k2uA-2vy0A: 19.68 1k2uB-2vy0A: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIF_A_BEZA349_0 (D-AMINO ACID OXIDASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 5	TYR A 250 TYR A 193 ILE A 199 GLY A 249	None	1.21A	1kifA-2vy0A: undetectable	1kifA-2vy0A: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIF_B_BEZB349_0 (D-AMINO ACID OXIDASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 5	TYR A 250 TYR A 193 ILE A 199 GLY A 249	None	1.21A	1kifB-2vy0A: undetectable	1kifB-2vy0A: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIF_C_BEZC349_0 (D-AMINO ACID OXIDASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 5	TYR A 250 TYR A 193 ILE A 199 GLY A 249	None	1.21A	1kifC-2vy0A: undetectable	1kifC-2vy0A: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIF_D_BEZD349_0 (D-AMINO ACID OXIDASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 5	TYR A 250 TYR A 193 ILE A 199 GLY A 249	None	1.21A	1kifD-2vy0A: undetectable	1kifD-2vy0A: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIF_E_BEZE349_0 (D-AMINO ACID OXIDASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 5	TYR A 250 TYR A 193 ILE A 199 GLY A 249	None	1.21A	1kifE-2vy0A: undetectable	1kifE-2vy0A: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIF_F_BEZF349_0 (D-AMINO ACID OXIDASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 5	TYR A 250 TYR A 193 ILE A 199 GLY A 249	None	1.21A	1kifF-2vy0A: undetectable	1kifF-2vy0A: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIF_G_BEZG349_0 (D-AMINO ACID OXIDASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 5	TYR A 250 TYR A 193 ILE A 199 GLY A 249	None	1.21A	1kifG-2vy0A: undetectable	1kifG-2vy0A: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIF_H_BEZH349_0 (D-AMINO ACID OXIDASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 5	TYR A 250 TYR A 193 ILE A 199 GLY A 249	None	1.21A	1kifH-2vy0A: undetectable	1kifH-2vy0A: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LZX_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	1lzxA-2vy0A: undetectable 1lzxB-2vy0A: undetectable	1lzxA-2vy0A: 19.68 1lzxB-2vy0A: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LZX_B_H4BB1760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	1lzxA-2vy0A: undetectable 1lzxB-2vy0A: undetectable	1lzxA-2vy0A: 19.68 1lzxB-2vy0A: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LZZ_B_H4BB1760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.40A	1lzzA-2vy0A: undetectable 1lzzB-2vy0A: undetectable	1lzzA-2vy0A: 19.68 1lzzB-2vy0A: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M00_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	1m00A-2vy0A: undetectable 1m00B-2vy0A: undetectable	1m00A-2vy0A: 19.68 1m00B-2vy0A: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M00_B_H4BB1760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	1m00A-2vy0A: undetectable 1m00B-2vy0A: undetectable	1m00A-2vy0A: 19.68 1m00B-2vy0A: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MF1_A_ACTA458_0 (ADENYLOSUCCINATE SYNTHETASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 4	GLY A 148 LYS A 147 GLY A 178 HIS A 179	None	1.07A	1mf1A-2vy0A: undetectable	1mf1A-2vy0A: 21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MMV_A_H4BA1760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	1mmvA-2vy0A: undetectable 1mmvB-2vy0A: undetectable	1mmvA-2vy0A: 19.68 1mmvB-2vy0A: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MMW_A_H4BA1760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	1mmwA-2vy0A: undetectable 1mmwB-2vy0A: undetectable	1mmwA-2vy0A: 19.68 1mmwB-2vy0A: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MMW_B_H4BB2760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	1mmwA-2vy0A: undetectable 1mmwB-2vy0A: undetectable	1mmwA-2vy0A: 19.68 1mmwB-2vy0A: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OM4_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	1om4A-2vy0A: undetectable 1om4B-2vy0A: undetectable	1om4A-2vy0A: 20.00 1om4B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OM4_B_H4BB761_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	1om4A-2vy0A: undetectable 1om4B-2vy0A: undetectable	1om4A-2vy0A: 20.00 1om4B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OM5_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 8	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	1om5A-2vy0A: undetectable 1om5B-2vy0A: undetectable	1om5A-2vy0A: 19.82 1om5B-2vy0A: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P6H_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.40A	1p6hA-2vy0A: undetectable 1p6hB-2vy0A: undetectable	1p6hA-2vy0A: 19.82 1p6hB-2vy0A: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P6H_B_H4BB761_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	1p6hA-2vy0A: undetectable 1p6hB-2vy0A: undetectable	1p6hA-2vy0A: 19.82 1p6hB-2vy0A: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P6I_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.39A	1p6iA-2vy0A: undetectable 1p6iB-2vy0A: undetectable	1p6iA-2vy0A: 19.82 1p6iB-2vy0A: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P6I_B_H4BB761_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.40A	1p6iA-2vy0A: undetectable 1p6iB-2vy0A: undetectable	1p6iA-2vy0A: 19.82 1p6iB-2vy0A: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P6J_B_H4BB761_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	1p6jA-2vy0A: undetectable 1p6jB-2vy0A: undetectable	1p6jA-2vy0A: 19.82 1p6jB-2vy0A: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P6K_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	1p6kA-2vy0A: undetectable 1p6kB-2vy0A: undetectable	1p6kA-2vy0A: 19.82 1p6kB-2vy0A: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P6K_B_H4BB761_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	1p6kA-2vy0A: undetectable 1p6kB-2vy0A: undetectable	1p6kA-2vy0A: 19.82 1p6kB-2vy0A: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RS6_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	1rs6A-2vy0A: undetectable 1rs6B-2vy0A: undetectable	1rs6A-2vy0A: 19.82 1rs6B-2vy0A: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RS6_B_H4BB761_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 8	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	1rs6A-2vy0A: undetectable 1rs6B-2vy0A: undetectable	1rs6A-2vy0A: 19.82 1rs6B-2vy0A: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RS7_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	1rs7A-2vy0A: undetectable 1rs7B-2vy0A: undetectable	1rs7A-2vy0A: 19.82 1rs7B-2vy0A: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RS7_B_H4BB761_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	1rs7A-2vy0A: undetectable 1rs7B-2vy0A: undetectable	1rs7A-2vy0A: 19.82 1rs7B-2vy0A: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VE9_A_BEZA352_0 (D-AMINO ACID OXIDASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 5	TYR A 250 TYR A 193 ILE A 199 GLY A 249	None	1.23A	1ve9A-2vy0A: undetectable	1ve9A-2vy0A: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VM1_A_TAZA504_1 (BETA-LACTAMASE SHV-1)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	3 / 3	ASP A 226 TYR A 224 GLU A 239	None	0.67A	1vm1A-2vy0A: undetectable	1vm1A-2vy0A: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WG8_A_SAMA3142_1 (PREDICTED S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 4	HIS A 217 ASP A 287 ASN A  96 ASP A 215	None CA  A1298 (-3.3A) None None	1.14A	1wg8A-2vy0A: undetectable	1wg8A-2vy0A: 21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZVL_A_H4BA900_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	1zvlA-2vy0A: undetectable 1zvlB-2vy0A: undetectable	1zvlA-2vy0A: 20.05 1zvlB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZVL_B_H4BB920_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	1zvlA-2vy0A: 0.0 1zvlB-2vy0A: 0.0	1zvlA-2vy0A: 20.05 1zvlB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZZQ_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	1zzqA-2vy0A: undetectable 1zzqB-2vy0A: undetectable	1zzqA-2vy0A: 19.86 1zzqB-2vy0A: 19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZZQ_B_H4BB761_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	1zzqA-2vy0A: undetectable 1zzqB-2vy0A: undetectable	1zzqA-2vy0A: 19.86 1zzqB-2vy0A: 19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2D0K_A_FOLA1161_0 (DIHYDROFOLATE REDUCTASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	5 / 12	ILE A 141 LEU A 143 PRO A 144 ILE A 184 TYR A 237	None	0.93A	2d0kA-2vy0A: undetectable	2d0kA-2vy0A: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DU8_G_BEZG2352_0 (D-AMINO-ACID OXIDASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 5	TYR A 250 TYR A 193 ILE A 199 GLY A 249	None	1.17A	2du8G-2vy0A: undetectable	2du8G-2vy0A: 20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G6H_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 8	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	2g6hA-2vy0A: undetectable 2g6hB-2vy0A: undetectable	2g6hA-2vy0A: 19.86 2g6hB-2vy0A: 19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G6H_B_H4BB761_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.40A	2g6hA-2vy0A: undetectable 2g6hB-2vy0A: undetectable	2g6hA-2vy0A: 19.86 2g6hB-2vy0A: 19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G6K_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	2g6kA-2vy0A: undetectable 2g6kB-2vy0A: undetectable	2g6kA-2vy0A: 19.86 2g6kB-2vy0A: 19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G6K_B_H4BB761_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.40A	2g6kA-2vy0A: undetectable 2g6kB-2vy0A: undetectable	2g6kA-2vy0A: 19.86 2g6kB-2vy0A: 19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G6M_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.41A	2g6mA-2vy0A: undetectable 2g6mB-2vy0A: undetectable	2g6mA-2vy0A: 19.86 2g6mB-2vy0A: 19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G6M_B_H4BB761_1 (NITRIC-OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	2g6mA-2vy0A: undetectable 2g6mB-2vy0A: undetectable	2g6mA-2vy0A: 19.86 2g6mB-2vy0A: 19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HX3_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	2hx3A-2vy0A: undetectable 2hx3B-2vy0A: undetectable	2hx3A-2vy0A: 20.00 2hx3B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HX3_B_H4BB760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	2hx3A-2vy0A: undetectable 2hx3B-2vy0A: undetectable	2hx3A-2vy0A: 20.00 2hx3B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HX4_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	2hx4A-2vy0A: undetectable 2hx4B-2vy0A: undetectable	2hx4A-2vy0A: 20.00 2hx4B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HX4_B_H4BB760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	2hx4A-2vy0A: undetectable 2hx4B-2vy0A: undetectable	2hx4A-2vy0A: 20.00 2hx4B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2KUH_A_HLTA150_1 (CALMODULIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	LEU A 143 MET A 284 GLU A 175 MET A 174	None None MPD  A1299 (-3.4A) None	1.06A	2kuhA-2vy0A: undetectable	2kuhA-2vy0A: 15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W8Y_A_486A1000_2 (PROGESTERONE RECEPTOR)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	LEU A 123 GLU A 126 LEU A 156 MET A 284	None	1.22A	2w8yA-2vy0A: undetectable	2w8yA-2vy0A: 22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B3M_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	3b3mA-2vy0A: undetectable 3b3mB-2vy0A: undetectable	3b3mA-2vy0A: 20.00 3b3mB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B3M_B_H4BB760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	3b3mA-2vy0A: undetectable 3b3mB-2vy0A: undetectable	3b3mA-2vy0A: 20.00 3b3mB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B3N_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	3b3nA-2vy0A: undetectable 3b3nB-2vy0A: undetectable	3b3nA-2vy0A: 20.00 3b3nB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B3N_B_H4BB760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	3b3nA-2vy0A: undetectable 3b3nB-2vy0A: undetectable	3b3nA-2vy0A: 20.00 3b3nB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B3O_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	3b3oA-2vy0A: undetectable 3b3oB-2vy0A: undetectable	3b3oA-2vy0A: 20.00 3b3oB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B3O_B_H4BB760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	3b3oA-2vy0A: undetectable 3b3oB-2vy0A: undetectable	3b3oA-2vy0A: 20.00 3b3oB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B3P_A_H4BA760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	3b3pA-2vy0A: undetectable 3b3pB-2vy0A: undetectable	3b3pA-2vy0A: 20.00 3b3pB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B3P_B_H4BB760_1 (NITRIC-OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 8	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.46A	3b3pA-2vy0A: undetectable 3b3pB-2vy0A: undetectable	3b3pA-2vy0A: 20.00 3b3pB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FC5_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	3fc5A-2vy0A: undetectable 3fc5B-2vy0A: undetectable	3fc5A-2vy0A: 20.00 3fc5B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FC5_B_H4BB761_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.40A	3fc5A-2vy0A: undetectable 3fc5B-2vy0A: undetectable	3fc5A-2vy0A: 20.00 3fc5B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWV_A_RFXA801_1 (TRANSPORTER)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	5 / 12	LEU A 123 LEU A 262 ARG A 122 ILE A 101 ALA A 152	None None MPD  A1299 (-3.7A) None MPD  A1299 ( 3.9A)	1.00A	3gwvA-2vy0A: undetectable	3gwvA-2vy0A: 20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HSN_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	3hsnA-2vy0A: undetectable 3hsnB-2vy0A: undetectable	3hsnA-2vy0A: 20.00 3hsnB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HSN_B_H4BB1760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	3hsnA-2vy0A: undetectable 3hsnB-2vy0A: undetectable	3hsnA-2vy0A: 20.00 3hsnB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HSO_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	3hsoA-2vy0A: undetectable 3hsoB-2vy0A: undetectable	3hsoA-2vy0A: 20.00 3hsoB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HSO_B_H4BB1760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	3hsoA-2vy0A: undetectable 3hsoB-2vy0A: undetectable	3hsoA-2vy0A: 20.00 3hsoB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HSP_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	3hspA-2vy0A: undetectable 3hspB-2vy0A: undetectable	3hspA-2vy0A: 20.00 3hspB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HSP_B_H4BB1760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	3hspA-2vy0A: undetectable 3hspB-2vy0A: undetectable	3hspA-2vy0A: 20.00 3hspB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JT3_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.48A	3jt3A-2vy0A: undetectable 3jt3B-2vy0A: undetectable	3jt3A-2vy0A: 20.00 3jt3B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JT3_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.47A	3jt3A-2vy0A: undetectable 3jt3B-2vy0A: undetectable	3jt3A-2vy0A: 20.00 3jt3B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JT4_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	3jt4A-2vy0A: undetectable 3jt4B-2vy0A: undetectable	3jt4A-2vy0A: 20.00 3jt4B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JT4_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	3jt4A-2vy0A: undetectable 3jt4B-2vy0A: undetectable	3jt4A-2vy0A: 20.00 3jt4B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JT5_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	3jt5A-2vy0A: undetectable 3jt5B-2vy0A: undetectable	3jt5A-2vy0A: 20.00 3jt5B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JT5_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	3jt5A-2vy0A: undetectable 3jt5B-2vy0A: undetectable	3jt5A-2vy0A: 20.00 3jt5B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JT6_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	3jt6A-2vy0A: undetectable 3jt6B-2vy0A: undetectable	3jt6A-2vy0A: 20.00 3jt6B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JT6_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	3jt6A-2vy0A: undetectable 3jt6B-2vy0A: undetectable	3jt6A-2vy0A: 20.00 3jt6B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JT7_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	3jt7A-2vy0A: undetectable 3jt7B-2vy0A: undetectable	3jt7A-2vy0A: 20.00 3jt7B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JT7_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	3jt7A-2vy0A: undetectable 3jt7B-2vy0A: undetectable	3jt7A-2vy0A: 20.00 3jt7B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JT8_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	3jt8A-2vy0A: undetectable 3jt8B-2vy0A: undetectable	3jt8A-2vy0A: 20.00 3jt8B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JT8_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	3jt8A-2vy0A: undetectable 3jt8B-2vy0A: undetectable	3jt8A-2vy0A: 20.00 3jt8B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JT9_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	3jt9A-2vy0A: undetectable 3jt9B-2vy0A: undetectable	3jt9A-2vy0A: 20.00 3jt9B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JT9_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	3jt9A-2vy0A: undetectable 3jt9B-2vy0A: undetectable	3jt9A-2vy0A: 20.00 3jt9B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JTA_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	3jtaA-2vy0A: undetectable 3jtaB-2vy0A: undetectable	3jtaA-2vy0A: 20.00 3jtaB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JTA_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	3jtaA-2vy0A: undetectable 3jtaB-2vy0A: undetectable	3jtaA-2vy0A: 20.00 3jtaB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JWS_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	3jwsA-2vy0A: undetectable 3jwsB-2vy0A: undetectable	3jwsA-2vy0A: 20.00 3jwsB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JWS_B_H4BB761_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	3jwsA-2vy0A: undetectable 3jwsB-2vy0A: undetectable	3jwsA-2vy0A: 20.00 3jwsB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JWT_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	3jwtA-2vy0A: undetectable 3jwtB-2vy0A: undetectable	3jwtA-2vy0A: 20.00 3jwtB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JWT_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	3jwtA-2vy0A: undetectable 3jwtB-2vy0A: undetectable	3jwtA-2vy0A: 20.00 3jwtB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JWU_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	3jwuA-2vy0A: undetectable 3jwuB-2vy0A: undetectable	3jwuA-2vy0A: 20.00 3jwuB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JWU_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	3jwuA-2vy0A: undetectable 3jwuB-2vy0A: undetectable	3jwuA-2vy0A: 20.00 3jwuB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JWV_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.47A	3jwvA-2vy0A: undetectable 3jwvB-2vy0A: undetectable	3jwvA-2vy0A: 20.00 3jwvB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JWV_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.46A	3jwvA-2vy0A: undetectable 3jwvB-2vy0A: undetectable	3jwvA-2vy0A: 20.00 3jwvB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JX0_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	3jx0A-2vy0A: undetectable 3jx0B-2vy0A: undetectable	3jx0A-2vy0A: 20.00 3jx0B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JX0_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	3jx0A-2vy0A: undetectable 3jx0B-2vy0A: undetectable	3jx0A-2vy0A: 20.00 3jx0B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JX1_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	3jx1A-2vy0A: undetectable 3jx1B-2vy0A: undetectable	3jx1A-2vy0A: 20.00 3jx1B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_B_TFPB201_1 (PROTEIN S100-A4)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 8	GLY A 190 ILE A 228 PHE A 131 PHE A 258	None	1.05A	3ko0B-2vy0A: undetectable 3ko0J-2vy0A: undetectable	3ko0B-2vy0A: 17.32 3ko0J-2vy0A: 17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_M_TFPM201_1 (PROTEIN S100-A4)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	GLY A 186 PHE A 216 PHE A 219 GLY A 220	None	0.92A	3ko0M-2vy0A: undetectable 3ko0P-2vy0A: undetectable	3ko0M-2vy0A: 17.32 3ko0P-2vy0A: 17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_P_TFPP201_1 (PROTEIN S100-A4)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	PHE A 219 GLY A 220 GLY A 186 PHE A 216	None	0.92A	3ko0M-2vy0A: undetectable 3ko0P-2vy0A: undetectable	3ko0M-2vy0A: 17.32 3ko0P-2vy0A: 17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N2R_A_H4BA760_1 (NITRIC OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	3n2rA-2vy0A: undetectable 3n2rB-2vy0A: undetectable	3n2rA-2vy0A: 20.00 3n2rB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N2R_B_H4BB760_1 (NITRIC OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	3n2rA-2vy0A: undetectable 3n2rB-2vy0A: undetectable	3n2rA-2vy0A: 20.00 3n2rB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N5V_B_H4BB760_1 (NITRIC OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	3n5vA-2vy0A: undetectable 3n5vB-2vy0A: undetectable	3n5vA-2vy0A: 20.00 3n5vB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N5Y_A_H4BA760_1 (NITRIC OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	3n5yA-2vy0A: undetectable 3n5yB-2vy0A: undetectable	3n5yA-2vy0A: 20.00 3n5yB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N5Y_B_H4BB760_1 (NITRIC OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	3n5yA-2vy0A: undetectable 3n5yB-2vy0A: undetectable	3n5yA-2vy0A: 20.00 3n5yB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N5Z_A_H4BA760_1 (NITRIC OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	3n5zA-2vy0A: undetectable 3n5zB-2vy0A: undetectable	3n5zA-2vy0A: 20.00 3n5zB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N5Z_B_H4BB760_1 (NITRIC OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	3n5zA-2vy0A: undetectable 3n5zB-2vy0A: undetectable	3n5zA-2vy0A: 20.00 3n5zB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N61_A_H4BA760_1 (NITRIC OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	3n61A-2vy0A: undetectable 3n61B-2vy0A: undetectable	3n61A-2vy0A: 19.67 3n61B-2vy0A: 19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N65_A_H4BA760_1 (NITRIC OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	3n65A-2vy0A: undetectable 3n65B-2vy0A: undetectable	3n65A-2vy0A: 20.23 3n65B-2vy0A: 20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLK_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	3nlkA-2vy0A: undetectable 3nlkB-2vy0A: undetectable	3nlkA-2vy0A: 20.00 3nlkB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLK_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	3nlkA-2vy0A: undetectable 3nlkB-2vy0A: undetectable	3nlkA-2vy0A: 20.00 3nlkB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLM_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	3nlmA-2vy0A: undetectable 3nlmB-2vy0A: undetectable	3nlmA-2vy0A: 20.00 3nlmB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLM_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	3nlmA-2vy0A: undetectable 3nlmB-2vy0A: undetectable	3nlmA-2vy0A: 20.00 3nlmB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLN_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	3nlnA-2vy0A: undetectable 3nlnB-2vy0A: undetectable	3nlnA-2vy0A: 20.00 3nlnB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLO_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	3nloA-2vy0A: undetectable 3nloB-2vy0A: undetectable	3nloA-2vy0A: 20.00 3nloB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLO_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.46A	3nloA-2vy0A: undetectable 3nloB-2vy0A: undetectable	3nloA-2vy0A: 20.00 3nloB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLV_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	3nlvA-2vy0A: undetectable 3nlvB-2vy0A: undetectable	3nlvA-2vy0A: 20.00 3nlvB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLV_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	3nlvA-2vy0A: undetectable 3nlvB-2vy0A: undetectable	3nlvA-2vy0A: 20.00 3nlvB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLW_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	3nlwA-2vy0A: undetectable 3nlwB-2vy0A: undetectable	3nlwA-2vy0A: 20.00 3nlwB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLW_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	3nlwA-2vy0A: undetectable 3nlwB-2vy0A: undetectable	3nlwA-2vy0A: 20.00 3nlwB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLX_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	3nlxA-2vy0A: undetectable 3nlxB-2vy0A: undetectable	3nlxA-2vy0A: 20.00 3nlxB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLX_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	3nlxA-2vy0A: undetectable 3nlxB-2vy0A: undetectable	3nlxA-2vy0A: 20.00 3nlxB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLZ_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	3nlzA-2vy0A: undetectable 3nlzB-2vy0A: undetectable	3nlzA-2vy0A: 20.00 3nlzB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NLZ_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	3nlzA-2vy0A: undetectable 3nlzB-2vy0A: undetectable	3nlzA-2vy0A: 20.00 3nlzB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NM0_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	3nm0A-2vy0A: undetectable 3nm0B-2vy0A: undetectable	3nm0A-2vy0A: 20.00 3nm0B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NM0_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	3nm0A-2vy0A: undetectable 3nm0B-2vy0A: undetectable	3nm0A-2vy0A: 20.00 3nm0B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NNY_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	3nnyA-2vy0A: undetectable 3nnyB-2vy0A: undetectable	3nnyA-2vy0A: 20.00 3nnyB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NNZ_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	3nnzA-2vy0A: undetectable 3nnzB-2vy0A: undetectable	3nnzA-2vy0A: 20.00 3nnzB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NNZ_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	3nnzA-2vy0A: undetectable 3nnzB-2vy0A: undetectable	3nnzA-2vy0A: 20.00 3nnzB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PNE_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	3pneA-2vy0A: undetectable 3pneB-2vy0A: undetectable	3pneA-2vy0A: 20.00 3pneB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PNE_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	3pneA-2vy0A: undetectable 3pneB-2vy0A: undetectable	3pneA-2vy0A: 20.00 3pneB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PNF_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	3pnfA-2vy0A: undetectable 3pnfB-2vy0A: undetectable	3pnfA-2vy0A: 20.00 3pnfB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PNF_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	3pnfA-2vy0A: undetectable 3pnfB-2vy0A: undetectable	3pnfA-2vy0A: 20.00 3pnfB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PNG_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	3pngA-2vy0A: undetectable 3pngB-2vy0A: undetectable	3pngA-2vy0A: 20.00 3pngB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PNG_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	3pngA-2vy0A: undetectable 3pngB-2vy0A: undetectable	3pngA-2vy0A: 20.00 3pngB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q99_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	3q99A-2vy0A: undetectable 3q99B-2vy0A: undetectable	3q99A-2vy0A: 20.00 3q99B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q99_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	3q99A-2vy0A: undetectable 3q99B-2vy0A: undetectable	3q99A-2vy0A: 20.00 3q99B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q9A_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.41A	3q9aA-2vy0A: undetectable 3q9aB-2vy0A: undetectable	3q9aA-2vy0A: 20.00 3q9aB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q9A_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	3q9aA-2vy0A: undetectable 3q9aB-2vy0A: undetectable	3q9aA-2vy0A: 20.00 3q9aB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQJ_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	3rqjA-2vy0A: undetectable 3rqjB-2vy0A: undetectable	3rqjA-2vy0A: 20.00 3rqjB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQJ_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	3rqjA-2vy0A: undetectable 3rqjB-2vy0A: undetectable	3rqjA-2vy0A: 20.00 3rqjB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQK_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	3rqkA-2vy0A: undetectable 3rqkB-2vy0A: undetectable	3rqkA-2vy0A: 20.00 3rqkB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQK_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	3rqkA-2vy0A: undetectable 3rqkB-2vy0A: undetectable	3rqkA-2vy0A: 20.00 3rqkB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQL_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	3rqlA-2vy0A: undetectable 3rqlB-2vy0A: undetectable	3rqlA-2vy0A: 20.00 3rqlB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQM_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	3rqmA-2vy0A: undetectable 3rqmB-2vy0A: undetectable	3rqmA-2vy0A: 20.00 3rqmB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQM_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	3rqmA-2vy0A: undetectable 3rqmB-2vy0A: undetectable	3rqmA-2vy0A: 20.00 3rqmB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQN_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	3rqnA-2vy0A: undetectable 3rqnB-2vy0A: undetectable	3rqnA-2vy0A: 20.00 3rqnB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQN_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	3rqnA-2vy0A: undetectable 3rqnB-2vy0A: undetectable	3rqnA-2vy0A: 20.00 3rqnB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SVP_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	3svpA-2vy0A: undetectable 3svpB-2vy0A: undetectable	3svpA-2vy0A: 20.00 3svpB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SVP_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	3svpA-2vy0A: undetectable 3svpB-2vy0A: undetectable	3svpA-2vy0A: 20.00 3svpB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SVQ_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	3svqA-2vy0A: undetectable 3svqB-2vy0A: undetectable	3svqA-2vy0A: 20.00 3svqB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SVQ_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	3svqA-2vy0A: undetectable 3svqB-2vy0A: undetectable	3svqA-2vy0A: 20.00 3svqB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TYL_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	3tylA-2vy0A: undetectable 3tylB-2vy0A: undetectable	3tylA-2vy0A: 20.00 3tylB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TYL_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	3tylA-2vy0A: undetectable 3tylB-2vy0A: undetectable	3tylA-2vy0A: 20.00 3tylB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TYM_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	3tymA-2vy0A: undetectable 3tymB-2vy0A: undetectable	3tymA-2vy0A: 20.00 3tymB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TYM_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	3tymA-2vy0A: undetectable 3tymB-2vy0A: undetectable	3tymA-2vy0A: 20.00 3tymB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TYN_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	3tynA-2vy0A: undetectable 3tynB-2vy0A: undetectable	3tynA-2vy0A: 20.00 3tynB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TYN_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	3tynA-2vy0A: undetectable 3tynB-2vy0A: undetectable	3tynA-2vy0A: 20.00 3tynB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TYO_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	3tyoA-2vy0A: undetectable 3tyoB-2vy0A: undetectable	3tyoA-2vy0A: 20.00 3tyoB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TYO_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	3tyoA-2vy0A: undetectable 3tyoB-2vy0A: undetectable	3tyoA-2vy0A: 20.00 3tyoB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFO_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	3ufoA-2vy0A: undetectable 3ufoB-2vy0A: undetectable	3ufoA-2vy0A: 20.00 3ufoB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFP_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.48A	3ufpA-2vy0A: undetectable 3ufpB-2vy0A: undetectable	3ufpA-2vy0A: 20.00 3ufpB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFQ_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	3ufqA-2vy0A: undetectable 3ufqB-2vy0A: undetectable	3ufqA-2vy0A: 20.00 3ufqB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFQ_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	3ufqA-2vy0A: undetectable 3ufqB-2vy0A: undetectable	3ufqA-2vy0A: 20.00 3ufqB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFR_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.47A	3ufrA-2vy0A: undetectable 3ufrB-2vy0A: undetectable	3ufrA-2vy0A: 20.00 3ufrB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFS_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	3ufsA-2vy0A: undetectable 3ufsB-2vy0A: undetectable	3ufsA-2vy0A: 20.00 3ufsB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFS_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	3ufsA-2vy0A: undetectable 3ufsB-2vy0A: undetectable	3ufsA-2vy0A: 20.00 3ufsB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFT_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	3uftA-2vy0A: undetectable 3uftB-2vy0A: undetectable	3uftA-2vy0A: 20.00 3uftB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFT_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	3uftA-2vy0A: undetectable 3uftB-2vy0A: undetectable	3uftA-2vy0A: 20.00 3uftB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFU_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	3ufuA-2vy0A: undetectable 3ufuB-2vy0A: undetectable	3ufuA-2vy0A: 20.00 3ufuB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFU_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	3ufuA-2vy0A: undetectable 3ufuB-2vy0A: undetectable	3ufuA-2vy0A: 20.00 3ufuB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFV_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	3ufvA-2vy0A: undetectable 3ufvB-2vy0A: undetectable	3ufvA-2vy0A: 20.00 3ufvB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFV_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	3ufvA-2vy0A: undetectable 3ufvB-2vy0A: undetectable	3ufvA-2vy0A: 20.00 3ufvB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFW_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.47A	3ufwA-2vy0A: undetectable 3ufwB-2vy0A: undetectable	3ufwA-2vy0A: 20.00 3ufwB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFW_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	3ufwA-2vy0A: undetectable 3ufwB-2vy0A: undetectable	3ufwA-2vy0A: 20.00 3ufwB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C39_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	4c39A-2vy0A: undetectable 4c39B-2vy0A: undetectable	4c39A-2vy0A: 20.00 4c39B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C39_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	4c39A-2vy0A: undetectable 4c39B-2vy0A: undetectable	4c39A-2vy0A: 20.00 4c39B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CAM_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	4camA-2vy0A: undetectable 4camB-2vy0A: undetectable	4camA-2vy0A: 20.00 4camB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CAN_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	4canA-2vy0A: undetectable 4canB-2vy0A: undetectable	4canA-2vy0A: 20.00 4canB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CAO_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.47A	4caoA-2vy0A: undetectable 4caoB-2vy0A: undetectable	4caoA-2vy0A: 20.00 4caoB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CAP_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.47A	4capA-2vy0A: undetectable 4capB-2vy0A: undetectable	4capA-2vy0A: 20.00 4capB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CAQ_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	4caqA-2vy0A: undetectable 4caqB-2vy0A: undetectable	4caqA-2vy0A: 20.00 4caqB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CAQ_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	4caqA-2vy0A: undetectable 4caqB-2vy0A: undetectable	4caqA-2vy0A: 20.00 4caqB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CDT_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.48A	4cdtA-2vy0A: undetectable 4cdtB-2vy0A: undetectable	4cdtA-2vy0A: 20.00 4cdtB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CDT_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.46A	4cdtA-2vy0A: undetectable 4cdtB-2vy0A: undetectable	4cdtA-2vy0A: 20.00 4cdtB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTP_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	4ctpA-2vy0A: undetectable 4ctpB-2vy0A: undetectable	4ctpA-2vy0A: 20.00 4ctpB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTQ_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	4ctqA-2vy0A: undetectable 4ctqB-2vy0A: undetectable	4ctqA-2vy0A: 20.00 4ctqB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTQ_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	4ctqA-2vy0A: undetectable 4ctqB-2vy0A: undetectable	4ctqA-2vy0A: 20.00 4ctqB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTR_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	4ctrA-2vy0A: undetectable 4ctrB-2vy0A: undetectable	4ctrA-2vy0A: 20.00 4ctrB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTR_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	4ctrA-2vy0A: undetectable 4ctrB-2vy0A: undetectable	4ctrA-2vy0A: 20.00 4ctrB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTT_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	4cttA-2vy0A: undetectable 4cttB-2vy0A: undetectable	4cttA-2vy0A: 20.00 4cttB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTT_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	4cttA-2vy0A: undetectable 4cttB-2vy0A: undetectable	4cttA-2vy0A: 20.00 4cttB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTU_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	4ctuA-2vy0A: undetectable 4ctuB-2vy0A: undetectable	4ctuA-2vy0A: 20.00 4ctuB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTU_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	4ctuA-2vy0A: undetectable 4ctuB-2vy0A: undetectable	4ctuA-2vy0A: 20.00 4ctuB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTV_B_H4BB1720_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	4ctvA-2vy0A: undetectable 4ctvB-2vy0A: undetectable	4ctvA-2vy0A: 20.00 4ctvB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTW_A_H4BA1718_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	4ctwA-2vy0A: undetectable 4ctwB-2vy0A: undetectable	4ctwA-2vy0A: 20.00 4ctwB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTW_B_H4BB1720_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	4ctwA-2vy0A: undetectable 4ctwB-2vy0A: undetectable	4ctwA-2vy0A: 20.00 4ctwB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTX_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	4ctxA-2vy0A: undetectable 4ctxB-2vy0A: undetectable	4ctxA-2vy0A: 20.00 4ctxB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTX_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	4ctxA-2vy0A: undetectable 4ctxB-2vy0A: undetectable	4ctxA-2vy0A: 20.00 4ctxB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CX5_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	4cx5A-2vy0A: undetectable 4cx5B-2vy0A: undetectable	4cx5A-2vy0A: 20.00 4cx5B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CX5_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	4cx5A-2vy0A: undetectable 4cx5B-2vy0A: undetectable	4cx5A-2vy0A: 20.00 4cx5B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CX6_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	4cx6A-2vy0A: undetectable 4cx6B-2vy0A: undetectable	4cx6A-2vy0A: 20.00 4cx6B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CX6_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	4cx6A-2vy0A: undetectable 4cx6B-2vy0A: undetectable	4cx6A-2vy0A: 20.00 4cx6B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D1N_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.41A	4d1nA-2vy0A: undetectable 4d1nB-2vy0A: undetectable	4d1nA-2vy0A: 20.28 4d1nB-2vy0A: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D1N_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	4d1nA-2vy0A: undetectable 4d1nB-2vy0A: undetectable	4d1nA-2vy0A: 20.28 4d1nB-2vy0A: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D1N_C_H4BC760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	4d1nC-2vy0A: undetectable 4d1nD-2vy0A: undetectable	4d1nC-2vy0A: 20.28 4d1nD-2vy0A: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D1N_D_H4BD760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	4d1nC-2vy0A: undetectable 4d1nD-2vy0A: undetectable	4d1nC-2vy0A: 20.28 4d1nD-2vy0A: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D2Y_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	4d2yA-2vy0A: undetectable 4d2yB-2vy0A: undetectable	4d2yA-2vy0A: 20.00 4d2yB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D2Y_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	4d2yA-2vy0A: undetectable 4d2yB-2vy0A: undetectable	4d2yA-2vy0A: 20.00 4d2yB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D2Z_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	4d2zA-2vy0A: undetectable 4d2zB-2vy0A: undetectable	4d2zA-2vy0A: 20.00 4d2zB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D2Z_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	4d2zA-2vy0A: undetectable 4d2zB-2vy0A: undetectable	4d2zA-2vy0A: 20.00 4d2zB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D30_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	4d30A-2vy0A: undetectable 4d30B-2vy0A: undetectable	4d30A-2vy0A: 20.00 4d30B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D30_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	4d30A-2vy0A: undetectable 4d30B-2vy0A: undetectable	4d30A-2vy0A: 20.00 4d30B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D31_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	4d31A-2vy0A: undetectable 4d31B-2vy0A: undetectable	4d31A-2vy0A: 20.00 4d31B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D31_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	4d31A-2vy0A: undetectable 4d31B-2vy0A: undetectable	4d31A-2vy0A: 20.00 4d31B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D32_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	4d32A-2vy0A: undetectable 4d32B-2vy0A: undetectable	4d32A-2vy0A: 20.00 4d32B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D3B_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	4d3bA-2vy0A: undetectable 4d3bB-2vy0A: undetectable	4d3bA-2vy0A: 20.00 4d3bB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D3B_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	4d3bA-2vy0A: undetectable 4d3bB-2vy0A: undetectable	4d3bA-2vy0A: 20.00 4d3bB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D7O_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	4d7oA-2vy0A: undetectable 4d7oB-2vy0A: undetectable	4d7oA-2vy0A: 20.00 4d7oB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D7O_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	4d7oA-2vy0A: undetectable 4d7oB-2vy0A: undetectable	4d7oA-2vy0A: 20.00 4d7oB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EUX_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	4euxA-2vy0A: undetectable 4euxB-2vy0A: undetectable	4euxA-2vy0A: 20.00 4euxB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EUX_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	4euxA-2vy0A: undetectable 4euxB-2vy0A: undetectable	4euxA-2vy0A: 20.00 4euxB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FVW_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	4fvwA-2vy0A: undetectable 4fvwB-2vy0A: undetectable	4fvwA-2vy0A: 20.00 4fvwB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FVW_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	4fvwA-2vy0A: undetectable 4fvwB-2vy0A: undetectable	4fvwA-2vy0A: 20.00 4fvwB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FVX_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	4fvxA-2vy0A: undetectable 4fvxB-2vy0A: undetectable	4fvxA-2vy0A: 20.00 4fvxB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FVY_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	4fvyA-2vy0A: undetectable 4fvyB-2vy0A: undetectable	4fvyA-2vy0A: 20.00 4fvyB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FVY_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	4fvyA-2vy0A: undetectable 4fvyB-2vy0A: undetectable	4fvyA-2vy0A: 20.00 4fvyB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FVZ_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.39A	4fvzA-2vy0A: undetectable 4fvzB-2vy0A: undetectable	4fvzA-2vy0A: 20.00 4fvzB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FVZ_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	4fvzA-2vy0A: undetectable 4fvzB-2vy0A: undetectable	4fvzA-2vy0A: 20.00 4fvzB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FW0_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	4fw0A-2vy0A: undetectable 4fw0B-2vy0A: undetectable	4fw0A-2vy0A: 20.00 4fw0B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FW0_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	4fw0A-2vy0A: undetectable 4fw0B-2vy0A: undetectable	4fw0A-2vy0A: 20.00 4fw0B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GQE_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	4gqeA-2vy0A: undetectable 4gqeB-2vy0A: undetectable	4gqeA-2vy0A: 20.00 4gqeB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GQE_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	4gqeA-2vy0A: undetectable 4gqeB-2vy0A: undetectable	4gqeA-2vy0A: 20.00 4gqeB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IMT_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	4imtA-2vy0A: undetectable 4imtB-2vy0A: undetectable	4imtA-2vy0A: 20.00 4imtB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IMT_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	4imtA-2vy0A: undetectable 4imtB-2vy0A: undetectable	4imtA-2vy0A: 20.00 4imtB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IMU_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	4imuA-2vy0A: undetectable 4imuB-2vy0A: undetectable	4imuA-2vy0A: 20.00 4imuB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IMU_A_H4BA809_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	4imuA-2vy0A: 0.0 4imuB-2vy0A: 0.0	4imuA-2vy0A: 20.00 4imuB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IMW_A_H4BA805_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	4imwA-2vy0A: undetectable 4imwB-2vy0A: undetectable	4imwA-2vy0A: 20.00 4imwB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IOM_A_FOLA608_0 (FORMATE--TETRAHYDROF OLATE LIGASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	ALA A 103 PRO A 281 LEU A 149 LEU A 264	None	0.90A	4iomA-2vy0A: undetectable	4iomA-2vy0A: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JJK_A_FOLA601_0 (FORMATE--TETRAHYDROF OLATE LIGASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 8	ALA A 103 PRO A 281 LEU A 149 LEU A 264	None	0.87A	4jjkA-2vy0A: undetectable	4jjkA-2vy0A: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JSE_A_H4BA804_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	4jseA-2vy0A: undetectable 4jseB-2vy0A: undetectable	4jseA-2vy0A: 20.00 4jseB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JSE_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	4jseA-2vy0A: undetectable 4jseB-2vy0A: undetectable	4jseA-2vy0A: 20.00 4jseB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JSF_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	4jsfA-2vy0A: undetectable 4jsfB-2vy0A: undetectable	4jsfA-2vy0A: 20.00 4jsfB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JSF_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	4jsfA-2vy0A: undetectable 4jsfB-2vy0A: undetectable	4jsfA-2vy0A: 20.00 4jsfB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JSG_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	4jsgA-2vy0A: undetectable 4jsgB-2vy0A: undetectable	4jsgA-2vy0A: 20.00 4jsgB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JSG_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	4jsgA-2vy0A: undetectable 4jsgB-2vy0A: undetectable	4jsgA-2vy0A: 20.00 4jsgB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JSH_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	4jshA-2vy0A: undetectable 4jshB-2vy0A: undetectable	4jshA-2vy0A: 20.00 4jshB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JSH_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.46A	4jshA-2vy0A: undetectable 4jshB-2vy0A: undetectable	4jshA-2vy0A: 20.00 4jshB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JSI_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	4jsiA-2vy0A: undetectable 4jsiB-2vy0A: undetectable	4jsiA-2vy0A: 20.00 4jsiB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JSJ_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	4jsjA-2vy0A: undetectable 4jsjB-2vy0A: undetectable	4jsjA-2vy0A: 20.00 4jsjB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JSJ_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	4jsjA-2vy0A: undetectable 4jsjB-2vy0A: undetectable	4jsjA-2vy0A: 20.00 4jsjB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K5D_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	4k5dA-2vy0A: undetectable 4k5dB-2vy0A: undetectable	4k5dA-2vy0A: 20.00 4k5dB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K5D_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	4k5dA-2vy0A: undetectable 4k5dB-2vy0A: undetectable	4k5dA-2vy0A: 20.00 4k5dB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K5E_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	4k5eA-2vy0A: undetectable 4k5eB-2vy0A: undetectable	4k5eA-2vy0A: 20.00 4k5eB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K5E_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	4k5eA-2vy0A: undetectable 4k5eB-2vy0A: undetectable	4k5eA-2vy0A: 20.00 4k5eB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K5F_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	4k5fA-2vy0A: undetectable 4k5fB-2vy0A: undetectable	4k5fA-2vy0A: 20.00 4k5fB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K5F_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	4k5fA-2vy0A: undetectable 4k5fB-2vy0A: undetectable	4k5fA-2vy0A: 20.00 4k5fB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K5G_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	4k5gA-2vy0A: undetectable 4k5gB-2vy0A: undetectable	4k5gA-2vy0A: 20.00 4k5gB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K5G_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	4k5gA-2vy0A: undetectable 4k5gB-2vy0A: undetectable	4k5gA-2vy0A: 20.00 4k5gB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCH_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	4kchA-2vy0A: undetectable 4kchB-2vy0A: undetectable	4kchA-2vy0A: 20.00 4kchB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCH_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	4kchA-2vy0A: undetectable 4kchB-2vy0A: undetectable	4kchA-2vy0A: 20.00 4kchB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCI_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	4kciA-2vy0A: undetectable 4kciB-2vy0A: undetectable	4kciA-2vy0A: 20.00 4kciB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCI_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	4kciA-2vy0A: undetectable 4kciB-2vy0A: undetectable	4kciA-2vy0A: 20.00 4kciB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCJ_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	4kcjA-2vy0A: undetectable 4kcjB-2vy0A: undetectable	4kcjA-2vy0A: 20.00 4kcjB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCJ_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	4kcjA-2vy0A: undetectable 4kcjB-2vy0A: undetectable	4kcjA-2vy0A: 20.00 4kcjB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCK_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	4kckA-2vy0A: undetectable 4kckB-2vy0A: undetectable	4kckA-2vy0A: 20.00 4kckB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCK_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.47A	4kckA-2vy0A: undetectable 4kckB-2vy0A: undetectable	4kckA-2vy0A: 20.00 4kckB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCL_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	4kclA-2vy0A: undetectable 4kclB-2vy0A: undetectable	4kclA-2vy0A: 20.00 4kclB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCL_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	4kclA-2vy0A: undetectable 4kclB-2vy0A: undetectable	4kclA-2vy0A: 20.00 4kclB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCM_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	4kcmA-2vy0A: undetectable 4kcmB-2vy0A: undetectable	4kcmA-2vy0A: 20.00 4kcmB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCM_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	4kcmA-2vy0A: undetectable 4kcmB-2vy0A: undetectable	4kcmA-2vy0A: 20.00 4kcmB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCN_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	4kcnA-2vy0A: undetectable 4kcnB-2vy0A: undetectable	4kcnA-2vy0A: 20.00 4kcnB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCN_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	4kcnA-2vy0A: undetectable 4kcnB-2vy0A: undetectable	4kcnA-2vy0A: 20.00 4kcnB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCO_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	4kcoA-2vy0A: undetectable 4kcoB-2vy0A: undetectable	4kcoA-2vy0A: 20.00 4kcoB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCO_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	4kcoA-2vy0A: undetectable 4kcoB-2vy0A: undetectable	4kcoA-2vy0A: 20.00 4kcoB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LUX_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	4luxA-2vy0A: undetectable 4luxB-2vy0A: undetectable	4luxA-2vy0A: 20.00 4luxB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LUX_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	4luxA-2vy0A: undetectable 4luxB-2vy0A: undetectable	4luxA-2vy0A: 20.00 4luxB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R87_J_SPMJ202_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	MET A 174 GLU A 175 GLU A  83 ARG A 122	None MPD  A1299 (-3.4A) MPD  A1299 (-4.2A) MPD  A1299 (-3.7A)	1.32A	4r87J-2vy0A: undetectable 4r87L-2vy0A: undetectable	4r87J-2vy0A: 18.94 4r87L-2vy0A: 18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RYA_A_MTLA501_1 (ABC TRANSPORTER SUBSTRATE BINDING PROTEIN (SORBITOL))	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	3 / 3	GLU A  53 TYR A 292 GLU A 138	None	0.82A	4ryaA-2vy0A: undetectable	4ryaA-2vy0A: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCH_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	4uchA-2vy0A: undetectable 4uchB-2vy0A: undetectable	4uchA-2vy0A: 20.23 4uchB-2vy0A: 20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCH_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 8	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	4uchA-2vy0A: undetectable 4uchB-2vy0A: undetectable	4uchA-2vy0A: 20.23 4uchB-2vy0A: 20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UGZ_A_H4BA760_1 (NEURONAL NITRIC OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	4ugzA-2vy0A: undetectable 4ugzB-2vy0A: undetectable	4ugzA-2vy0A: 20.00 4ugzB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UGZ_B_H4BB760_1 (NEURONAL NITRIC OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	4ugzA-2vy0A: undetectable 4ugzB-2vy0A: undetectable	4ugzA-2vy0A: 20.00 4ugzB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UH0_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	4uh0A-2vy0A: undetectable 4uh0B-2vy0A: undetectable	4uh0A-2vy0A: 20.00 4uh0B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UH0_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	4uh0A-2vy0A: undetectable 4uh0B-2vy0A: undetectable	4uh0A-2vy0A: 20.00 4uh0B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UH1_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	4uh1A-2vy0A: undetectable 4uh1B-2vy0A: undetectable	4uh1A-2vy0A: 20.00 4uh1B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UH1_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	4uh1A-2vy0A: undetectable 4uh1B-2vy0A: undetectable	4uh1A-2vy0A: 20.00 4uh1B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UH2_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	4uh2A-2vy0A: undetectable 4uh2B-2vy0A: undetectable	4uh2A-2vy0A: 20.00 4uh2B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UH2_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	4uh2A-2vy0A: undetectable 4uh2B-2vy0A: undetectable	4uh2A-2vy0A: 20.00 4uh2B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UH3_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	4uh3A-2vy0A: undetectable 4uh3B-2vy0A: undetectable	4uh3A-2vy0A: 20.00 4uh3B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UH3_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	4uh3A-2vy0A: undetectable 4uh3B-2vy0A: undetectable	4uh3A-2vy0A: 20.00 4uh3B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UH4_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	4uh4A-2vy0A: undetectable 4uh4B-2vy0A: undetectable	4uh4A-2vy0A: 20.00 4uh4B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UH4_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	4uh4A-2vy0A: undetectable 4uh4B-2vy0A: undetectable	4uh4A-2vy0A: 20.00 4uh4B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UH5_A_H4BA760_1 (NEURONAL NITRIC OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	4uh5A-2vy0A: undetectable 4uh5B-2vy0A: undetectable	4uh5A-2vy0A: 20.05 4uh5B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UH5_B_H4BB760_1 (NEURONAL NITRIC OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	4uh5A-2vy0A: undetectable 4uh5B-2vy0A: undetectable	4uh5A-2vy0A: 20.05 4uh5B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UH6_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	4uh6A-2vy0A: undetectable 4uh6B-2vy0A: undetectable	4uh6A-2vy0A: 20.05 4uh6B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UH6_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	4uh6A-2vy0A: undetectable 4uh6B-2vy0A: undetectable	4uh6A-2vy0A: 20.05 4uh6B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UPM_A_H4BA760_1 (NEURONAL NITRIC OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	4upmA-2vy0A: undetectable 4upmB-2vy0A: undetectable	4upmA-2vy0A: 20.00 4upmB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UPM_B_H4BB760_1 (NEURONAL NITRIC OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	4upmA-2vy0A: undetectable 4upmB-2vy0A: undetectable	4upmA-2vy0A: 20.00 4upmB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UPN_A_H4BA760_1 (NEURONAL NITRIC OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	4upnA-2vy0A: undetectable 4upnB-2vy0A: undetectable	4upnA-2vy0A: 20.00 4upnB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UPN_B_H4BB760_1 (NEURONAL NITRIC OXIDE SYNTHASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	4upnA-2vy0A: undetectable 4upnB-2vy0A: undetectable	4upnA-2vy0A: 20.00 4upnB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UPO_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	4upoA-2vy0A: undetectable 4upoB-2vy0A: undetectable	4upoA-2vy0A: 20.00 4upoB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UPO_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	4upoA-2vy0A: undetectable 4upoB-2vy0A: undetectable	4upoA-2vy0A: 20.00 4upoB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UPP_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	4uppA-2vy0A: undetectable 4uppB-2vy0A: undetectable	4uppA-2vy0A: 20.00 4uppB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UPP_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	4uppA-2vy0A: undetectable 4uppB-2vy0A: undetectable	4uppA-2vy0A: 20.00 4uppB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V3U_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.41A	4v3uA-2vy0A: undetectable 4v3uB-2vy0A: undetectable	4v3uA-2vy0A: 20.28 4v3uB-2vy0A: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V3U_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	4v3uA-2vy0A: undetectable 4v3uB-2vy0A: undetectable	4v3uA-2vy0A: 20.28 4v3uB-2vy0A: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V3U_C_H4BC760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.40A	4v3uC-2vy0A: undetectable 4v3uD-2vy0A: undetectable	4v3uC-2vy0A: 20.28 4v3uD-2vy0A: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V3U_D_H4BD760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.39A	4v3uC-2vy0A: undetectable 4v3uD-2vy0A: undetectable	4v3uC-2vy0A: 20.28 4v3uD-2vy0A: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V3V_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	4v3vA-2vy0A: undetectable 4v3vB-2vy0A: undetectable	4v3vA-2vy0A: 20.00 4v3vB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V3W_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.38A	4v3wA-2vy0A: undetectable 4v3wB-2vy0A: undetectable	4v3wA-2vy0A: 20.00 4v3wB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V3W_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	4v3wA-2vy0A: undetectable 4v3wB-2vy0A: undetectable	4v3wA-2vy0A: 20.00 4v3wB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V3X_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	4v3xA-2vy0A: undetectable 4v3xB-2vy0A: undetectable	4v3xA-2vy0A: 20.00 4v3xB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V3X_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	4v3xA-2vy0A: undetectable 4v3xB-2vy0A: undetectable	4v3xA-2vy0A: 20.00 4v3xB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V3Y_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	4v3yA-2vy0A: undetectable 4v3yB-2vy0A: undetectable	4v3yA-2vy0A: 20.00 4v3yB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V3Z_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	4v3zA-2vy0A: undetectable 4v3zB-2vy0A: undetectable	4v3zA-2vy0A: 20.00 4v3zB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V3Z_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	4v3zA-2vy0A: undetectable 4v3zB-2vy0A: undetectable	4v3zA-2vy0A: 20.00 4v3zB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AD4_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	5ad4A-2vy0A: undetectable 5ad4B-2vy0A: undetectable	5ad4A-2vy0A: 20.00 5ad4B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AD4_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.47A	5ad4A-2vy0A: undetectable 5ad4B-2vy0A: undetectable	5ad4A-2vy0A: 20.00 5ad4B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AD5_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	5ad5A-2vy0A: undetectable 5ad5B-2vy0A: undetectable	5ad5A-2vy0A: 20.00 5ad5B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AD5_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	5ad5A-2vy0A: undetectable 5ad5B-2vy0A: undetectable	5ad5A-2vy0A: 20.00 5ad5B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AD6_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.48A	5ad6A-2vy0A: undetectable 5ad6B-2vy0A: undetectable	5ad6A-2vy0A: 20.00 5ad6B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AD6_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	5ad6A-2vy0A: undetectable 5ad6B-2vy0A: undetectable	5ad6A-2vy0A: 20.00 5ad6B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AD7_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	5ad7A-2vy0A: undetectable 5ad7B-2vy0A: undetectable	5ad7A-2vy0A: 20.00 5ad7B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AD8_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	5ad8A-2vy0A: undetectable 5ad8B-2vy0A: undetectable	5ad8A-2vy0A: 20.00 5ad8B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ADA_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	5adaA-2vy0A: undetectable 5adaB-2vy0A: undetectable	5adaA-2vy0A: 20.00 5adaB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ADA_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	5adaA-2vy0A: undetectable 5adaB-2vy0A: undetectable	5adaA-2vy0A: 20.00 5adaB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ADB_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	5adbA-2vy0A: undetectable 5adbB-2vy0A: undetectable	5adbA-2vy0A: 20.00 5adbB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ADC_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	5adcA-2vy0A: undetectable 5adcB-2vy0A: undetectable	5adcA-2vy0A: 20.00 5adcB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ADC_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	5adcA-2vy0A: undetectable 5adcB-2vy0A: undetectable	5adcA-2vy0A: 20.00 5adcB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ADF_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	5adfA-2vy0A: undetectable 5adfB-2vy0A: undetectable	5adfA-2vy0A: 20.05 5adfB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ADG_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.41A	5adgA-2vy0A: undetectable 5adgB-2vy0A: undetectable	5adgA-2vy0A: 20.05 5adgB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ADG_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	5adgA-2vy0A: undetectable 5adgB-2vy0A: undetectable	5adgA-2vy0A: 20.05 5adgB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ADI_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	5adiA-2vy0A: undetectable 5adiB-2vy0A: undetectable	5adiA-2vy0A: 20.05 5adiB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AGK_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	5agkA-2vy0A: undetectable 5agkB-2vy0A: undetectable	5agkA-2vy0A: 20.00 5agkB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AGL_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	5aglA-2vy0A: undetectable 5aglB-2vy0A: undetectable	5aglA-2vy0A: 20.00 5aglB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AGL_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	5aglA-2vy0A: undetectable 5aglB-2vy0A: undetectable	5aglA-2vy0A: 20.00 5aglB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AGM_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	5agmA-2vy0A: undetectable 5agmB-2vy0A: undetectable	5agmA-2vy0A: 20.00 5agmB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AGM_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	5agmA-2vy0A: undetectable 5agmB-2vy0A: undetectable	5agmA-2vy0A: 20.00 5agmB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AGN_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	5agnA-2vy0A: undetectable 5agnB-2vy0A: undetectable	5agnA-2vy0A: 20.00 5agnB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AGN_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	5agnA-2vy0A: undetectable 5agnB-2vy0A: undetectable	5agnA-2vy0A: 20.00 5agnB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AGO_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	5agoA-2vy0A: undetectable 5agoB-2vy0A: undetectable	5agoA-2vy0A: 20.00 5agoB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AGP_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	5agpA-2vy0A: undetectable 5agpB-2vy0A: undetectable	5agpA-2vy0A: 20.00 5agpB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AGP_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	5agpA-2vy0A: undetectable 5agpB-2vy0A: undetectable	5agpA-2vy0A: 20.00 5agpB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVP_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	5fvpA-2vy0A: undetectable 5fvpB-2vy0A: undetectable	5fvpA-2vy0A: 20.00 5fvpB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVP_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	5fvpA-2vy0A: undetectable 5fvpB-2vy0A: undetectable	5fvpA-2vy0A: 20.00 5fvpB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVQ_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.41A	5fvqA-2vy0A: undetectable 5fvqB-2vy0A: undetectable	5fvqA-2vy0A: 20.00 5fvqB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVQ_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	5fvqA-2vy0A: undetectable 5fvqB-2vy0A: undetectable	5fvqA-2vy0A: 20.00 5fvqB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVR_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	5fvrA-2vy0A: undetectable 5fvrB-2vy0A: undetectable	5fvrA-2vy0A: 20.00 5fvrB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVR_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	5fvrA-2vy0A: undetectable 5fvrB-2vy0A: undetectable	5fvrA-2vy0A: 20.00 5fvrB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVS_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	5fvsA-2vy0A: undetectable 5fvsB-2vy0A: undetectable	5fvsA-2vy0A: 20.00 5fvsB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVS_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	5fvsA-2vy0A: undetectable 5fvsB-2vy0A: undetectable	5fvsA-2vy0A: 20.00 5fvsB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVT_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	5fvtA-2vy0A: undetectable 5fvtB-2vy0A: undetectable	5fvtA-2vy0A: 20.00 5fvtB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVT_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	5fvtA-2vy0A: undetectable 5fvtB-2vy0A: undetectable	5fvtA-2vy0A: 20.00 5fvtB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVU_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	5fvuA-2vy0A: undetectable 5fvuB-2vy0A: undetectable	5fvuA-2vy0A: 20.05 5fvuB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVU_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	5fvuA-2vy0A: undetectable 5fvuB-2vy0A: undetectable	5fvuA-2vy0A: 20.05 5fvuB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVV_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.41A	5fvvA-2vy0A: undetectable 5fvvB-2vy0A: undetectable	5fvvA-2vy0A: 20.05 5fvvB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVV_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.40A	5fvvA-2vy0A: undetectable 5fvvB-2vy0A: undetectable	5fvvA-2vy0A: 20.05 5fvvB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVW_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	5fvwA-2vy0A: undetectable 5fvwB-2vy0A: undetectable	5fvwA-2vy0A: 20.05 5fvwB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVW_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	5fvwA-2vy0A: undetectable 5fvwB-2vy0A: undetectable	5fvwA-2vy0A: 20.05 5fvwB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FVX_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	5fvxA-2vy0A: undetectable 5fvxB-2vy0A: undetectable	5fvxA-2vy0A: 20.05 5fvxB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FW0_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	5fw0A-2vy0A: undetectable 5fw0B-2vy0A: undetectable	5fw0A-2vy0A: 20.00 5fw0B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FW0_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	5fw0A-2vy0A: undetectable 5fw0B-2vy0A: undetectable	5fw0A-2vy0A: 20.00 5fw0B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G0N_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.40A	5g0nA-2vy0A: undetectable 5g0nB-2vy0A: undetectable	5g0nA-2vy0A: 20.00 5g0nB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G0N_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	5g0nA-2vy0A: undetectable 5g0nB-2vy0A: undetectable	5g0nA-2vy0A: 20.00 5g0nB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G0O_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	5g0oA-2vy0A: undetectable 5g0oB-2vy0A: undetectable	5g0oA-2vy0A: 20.00 5g0oB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G0O_B_H4BB760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	5g0oA-2vy0A: undetectable 5g0oB-2vy0A: undetectable	5g0oA-2vy0A: 20.00 5g0oB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IK1_A_CAMA503_0 (CAMPHOR 5-MONOOXYGENASE)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	GLY A 234 VAL A 136 ILE A 221 VAL A 222	None	0.81A	5ik1A-2vy0A: undetectable	5ik1A-2vy0A: 19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNR_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	5unrA-2vy0A: undetectable 5unrB-2vy0A: undetectable	5unrA-2vy0A: 20.00 5unrB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNS_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	5unsA-2vy0A: undetectable 5unsB-2vy0A: undetectable	5unsA-2vy0A: 20.00 5unsB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNS_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	5unsA-2vy0A: undetectable 5unsB-2vy0A: undetectable	5unsA-2vy0A: 20.00 5unsB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNT_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	5untA-2vy0A: undetectable 5untB-2vy0A: undetectable	5untA-2vy0A: 20.00 5untB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNT_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	5untA-2vy0A: undetectable 5untB-2vy0A: undetectable	5untA-2vy0A: 20.00 5untB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNU_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	5unuA-2vy0A: undetectable 5unuB-2vy0A: undetectable	5unuA-2vy0A: 20.00 5unuB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNU_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	5unuA-2vy0A: undetectable 5unuB-2vy0A: undetectable	5unuA-2vy0A: 20.00 5unuB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNV_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.47A	5unvA-2vy0A: undetectable 5unvB-2vy0A: undetectable	5unvA-2vy0A: 20.00 5unvB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNV_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.50A	5unvA-2vy0A: undetectable 5unvB-2vy0A: undetectable	5unvA-2vy0A: 20.00 5unvB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNW_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	5unwA-2vy0A: undetectable 5unwB-2vy0A: undetectable	5unwA-2vy0A: 20.00 5unwB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNW_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.47A	5unwA-2vy0A: undetectable 5unwB-2vy0A: undetectable	5unwA-2vy0A: 20.00 5unwB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNX_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.48A	5unxA-2vy0A: undetectable 5unxB-2vy0A: undetectable	5unxA-2vy0A: 20.00 5unxB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNX_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	5unxA-2vy0A: undetectable 5unxB-2vy0A: undetectable	5unxA-2vy0A: 20.00 5unxB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNY_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	5unyA-2vy0A: undetectable 5unyB-2vy0A: undetectable	5unyA-2vy0A: 20.00 5unyB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNY_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	5unyA-2vy0A: undetectable 5unyB-2vy0A: undetectable	5unyA-2vy0A: 20.00 5unyB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNZ_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	5unzA-2vy0A: undetectable 5unzB-2vy0A: undetectable	5unzA-2vy0A: 20.00 5unzB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO0_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.47A	5uo0A-2vy0A: undetectable 5uo0B-2vy0A: undetectable	5uo0A-2vy0A: 20.00 5uo0B-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO1_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	5uo1A-2vy0A: undetectable 5uo1B-2vy0A: undetectable	5uo1A-2vy0A: 20.05 5uo1B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO1_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	5uo1A-2vy0A: undetectable 5uo1B-2vy0A: undetectable	5uo1A-2vy0A: 20.05 5uo1B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO2_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.41A	5uo2A-2vy0A: undetectable 5uo2B-2vy0A: undetectable	5uo2A-2vy0A: 20.05 5uo2B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO2_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	5uo2A-2vy0A: undetectable 5uo2B-2vy0A: undetectable	5uo2A-2vy0A: 20.05 5uo2B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO3_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	5uo3A-2vy0A: undetectable 5uo3B-2vy0A: undetectable	5uo3A-2vy0A: 20.05 5uo3B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO3_B_H4BB803_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	5uo3A-2vy0A: undetectable 5uo3B-2vy0A: undetectable	5uo3A-2vy0A: 20.05 5uo3B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO4_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	5uo4A-2vy0A: undetectable 5uo4B-2vy0A: undetectable	5uo4A-2vy0A: 20.05 5uo4B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO4_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	5uo4A-2vy0A: undetectable 5uo4B-2vy0A: undetectable	5uo4A-2vy0A: 20.05 5uo4B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO5_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	5uo5A-2vy0A: undetectable 5uo5B-2vy0A: undetectable	5uo5A-2vy0A: 20.05 5uo5B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO5_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	5uo5A-2vy0A: undetectable 5uo5B-2vy0A: undetectable	5uo5A-2vy0A: 20.05 5uo5B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO6_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.47A	5uo6A-2vy0A: undetectable 5uo6B-2vy0A: undetectable	5uo6A-2vy0A: 20.05 5uo6B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO7_B_H4BB803_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	5uo7A-2vy0A: undetectable 5uo7B-2vy0A: undetectable	5uo7A-2vy0A: 20.05 5uo7B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_A_ACTA303_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	3 / 3	GLU A  55 TYR A 288 ARG A 290	CA  A1298 (-3.9A) None None	0.80A	5uunA-2vy0A: undetectable	5uunA-2vy0A: 20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUI_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.47A	5vuiA-2vy0A: undetectable 5vuiB-2vy0A: undetectable	5vuiA-2vy0A: 20.00 5vuiB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUI_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	5vuiA-2vy0A: undetectable 5vuiB-2vy0A: undetectable	5vuiA-2vy0A: 20.00 5vuiB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUJ_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	5vujA-2vy0A: undetectable 5vujB-2vy0A: undetectable	5vujA-2vy0A: 20.00 5vujB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUK_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.47A	5vukA-2vy0A: undetectable 5vukB-2vy0A: undetectable	5vukA-2vy0A: 20.00 5vukB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUK_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	5vukA-2vy0A: undetectable 5vukB-2vy0A: undetectable	5vukA-2vy0A: 20.00 5vukB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUL_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	5vulA-2vy0A: undetectable 5vulB-2vy0A: undetectable	5vulA-2vy0A: 20.00 5vulB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUL_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	5vulA-2vy0A: undetectable 5vulB-2vy0A: undetectable	5vulA-2vy0A: 20.00 5vulB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUM_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	5vumA-2vy0A: undetectable 5vumB-2vy0A: undetectable	5vumA-2vy0A: 20.00 5vumB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUN_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	5vunA-2vy0A: undetectable 5vunB-2vy0A: undetectable	5vunA-2vy0A: 20.00 5vunB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUN_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	5vunA-2vy0A: undetectable 5vunB-2vy0A: undetectable	5vunA-2vy0A: 20.00 5vunB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUO_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	5vuoA-2vy0A: undetectable 5vuoB-2vy0A: undetectable	5vuoA-2vy0A: 20.00 5vuoB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUO_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	5vuoA-2vy0A: undetectable 5vuoB-2vy0A: undetectable	5vuoA-2vy0A: 20.00 5vuoB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUP_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	5vupA-2vy0A: undetectable 5vupB-2vy0A: undetectable	5vupA-2vy0A: 20.00 5vupB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUP_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	5vupA-2vy0A: undetectable 5vupB-2vy0A: undetectable	5vupA-2vy0A: 20.00 5vupB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUQ_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	5vuqA-2vy0A: undetectable 5vuqB-2vy0A: undetectable	5vuqA-2vy0A: 20.00 5vuqB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUQ_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	5vuqA-2vy0A: undetectable 5vuqB-2vy0A: undetectable	5vuqA-2vy0A: 20.00 5vuqB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUS_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	5vusA-2vy0A: undetectable 5vusB-2vy0A: undetectable	5vusA-2vy0A: 20.00 5vusB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUT_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.41A	5vutA-2vy0A: undetectable 5vutB-2vy0A: undetectable	5vutA-2vy0A: 20.00 5vutB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUT_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	5vutA-2vy0A: undetectable 5vutB-2vy0A: undetectable	5vutA-2vy0A: 20.00 5vutB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUU_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	5vuuA-2vy0A: undetectable 5vuuB-2vy0A: undetectable	5vuuA-2vy0A: 20.00 5vuuB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUU_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	5vuuA-2vy0A: undetectable 5vuuB-2vy0A: undetectable	5vuuA-2vy0A: 20.00 5vuuB-2vy0A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUV_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	5vuvA-2vy0A: undetectable 5vuvB-2vy0A: undetectable	5vuvA-2vy0A: 20.05 5vuvB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUW_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	5vuwA-2vy0A: undetectable 5vuwB-2vy0A: undetectable	5vuwA-2vy0A: 20.05 5vuwB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUW_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	5vuwA-2vy0A: undetectable 5vuwB-2vy0A: undetectable	5vuwA-2vy0A: 20.05 5vuwB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUX_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	5vuxA-2vy0A: undetectable 5vuxB-2vy0A: undetectable	5vuxA-2vy0A: 20.05 5vuxB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUY_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	5vuyA-2vy0A: undetectable 5vuyB-2vy0A: undetectable	5vuyA-2vy0A: 20.05 5vuyB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUY_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	5vuyA-2vy0A: undetectable 5vuyB-2vy0A: undetectable	5vuyA-2vy0A: 20.05 5vuyB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUZ_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	5vuzA-2vy0A: undetectable 5vuzB-2vy0A: undetectable	5vuzA-2vy0A: 20.05 5vuzB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUZ_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	5vuzA-2vy0A: undetectable 5vuzB-2vy0A: undetectable	5vuzA-2vy0A: 20.05 5vuzB-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VV0_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	5vv0A-2vy0A: undetectable 5vv0B-2vy0A: undetectable	5vv0A-2vy0A: 20.05 5vv0B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VV0_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	5vv0A-2vy0A: undetectable 5vv0B-2vy0A: undetectable	5vv0A-2vy0A: 20.05 5vv0B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VV1_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	5vv1A-2vy0A: undetectable 5vv1B-2vy0A: undetectable	5vv1A-2vy0A: 20.05 5vv1B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VV1_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	5vv1A-2vy0A: undetectable 5vv1B-2vy0A: undetectable	5vv1A-2vy0A: 20.05 5vv1B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VV2_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	5vv2A-2vy0A: undetectable 5vv2B-2vy0A: undetectable	5vv2A-2vy0A: 20.05 5vv2B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VV2_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	5vv2A-2vy0A: undetectable 5vv2B-2vy0A: undetectable	5vv2A-2vy0A: 20.05 5vv2B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VV3_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.46A	5vv3A-2vy0A: undetectable 5vv3B-2vy0A: undetectable	5vv3A-2vy0A: 20.05 5vv3B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VV3_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	5vv3A-2vy0A: undetectable 5vv3B-2vy0A: undetectable	5vv3A-2vy0A: 20.05 5vv3B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VV4_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	5vv4A-2vy0A: undetectable 5vv4B-2vy0A: undetectable	5vv4A-2vy0A: 20.05 5vv4B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VV5_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	5vv5A-2vy0A: undetectable 5vv5B-2vy0A: undetectable	5vv5A-2vy0A: 20.05 5vv5B-2vy0A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z84_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	3 / 3	TYR A 237 ARG A 201 THR A 204	None	0.96A	5z84J-2vy0A: undetectable	5z84J-2vy0A: 13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUQ_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 6	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.47A	6auqA-2vy0A: undetectable 6auqB-2vy0A: undetectable	6auqA-2vy0A: 15.73 6auqB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUQ_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	6auqA-2vy0A: undetectable 6auqB-2vy0A: undetectable	6auqA-2vy0A: 15.73 6auqB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUR_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	6aurA-2vy0A: undetectable 6aurB-2vy0A: undetectable	6aurA-2vy0A: 15.73 6aurB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUR_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	6aurA-2vy0A: undetectable 6aurB-2vy0A: undetectable	6aurA-2vy0A: 15.73 6aurB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUS_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	6ausA-2vy0A: undetectable 6ausB-2vy0A: undetectable	6ausA-2vy0A: 15.73 6ausB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUS_B_H4BB803_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.40A	6ausA-2vy0A: undetectable 6ausB-2vy0A: undetectable	6ausA-2vy0A: 15.73 6ausB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUT_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	6autA-2vy0A: undetectable 6autB-2vy0A: undetectable	6autA-2vy0A: 15.73 6autB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUT_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.40A	6autA-2vy0A: undetectable 6autB-2vy0A: undetectable	6autA-2vy0A: 15.73 6autB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUU_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	6auuA-2vy0A: undetectable 6auuB-2vy0A: undetectable	6auuA-2vy0A: 15.73 6auuB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUU_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	6auuA-2vy0A: undetectable 6auuB-2vy0A: undetectable	6auuA-2vy0A: 15.73 6auuB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUV_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	6auvA-2vy0A: undetectable 6auvB-2vy0A: undetectable	6auvA-2vy0A: 15.73 6auvB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUV_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	6auvA-2vy0A: undetectable 6auvB-2vy0A: undetectable	6auvA-2vy0A: 15.73 6auvB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUW_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	6auwA-2vy0A: undetectable 6auwB-2vy0A: undetectable	6auwA-2vy0A: 15.73 6auwB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUW_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	6auwA-2vy0A: undetectable 6auwB-2vy0A: undetectable	6auwA-2vy0A: 15.73 6auwB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUX_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	6auxA-2vy0A: undetectable 6auxB-2vy0A: undetectable	6auxA-2vy0A: 15.73 6auxB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUX_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	6auxA-2vy0A: undetectable 6auxB-2vy0A: undetectable	6auxA-2vy0A: 15.73 6auxB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUY_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.41A	6auyA-2vy0A: undetectable 6auyB-2vy0A: undetectable	6auyA-2vy0A: 15.73 6auyB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUY_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	6auyA-2vy0A: undetectable 6auyB-2vy0A: undetectable	6auyA-2vy0A: 15.73 6auyB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUZ_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.41A	6auzA-2vy0A: undetectable 6auzB-2vy0A: undetectable	6auzA-2vy0A: 15.73 6auzB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUZ_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	6auzA-2vy0A: undetectable 6auzB-2vy0A: undetectable	6auzA-2vy0A: 15.73 6auzB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV0_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.43A	6av0A-2vy0A: undetectable 6av0B-2vy0A: undetectable	6av0A-2vy0A: 15.73 6av0B-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV0_B_H4BB803_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	6av0A-2vy0A: undetectable 6av0B-2vy0A: undetectable	6av0A-2vy0A: 15.73 6av0B-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV1_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.45A	6av1A-2vy0A: undetectable 6av1B-2vy0A: undetectable	6av1A-2vy0A: 15.73 6av1B-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV1_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.45A	6av1A-2vy0A: undetectable 6av1B-2vy0A: undetectable	6av1A-2vy0A: 15.73 6av1B-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV2_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	6av2A-2vy0A: undetectable 6av2B-2vy0A: undetectable	6av2A-2vy0A: 15.73 6av2B-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV2_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.44A	6av2A-2vy0A: undetectable 6av2B-2vy0A: undetectable	6av2A-2vy0A: 15.73 6av2B-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV3_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	6av3A-2vy0A: undetectable 6av3B-2vy0A: undetectable	6av3A-2vy0A: 15.73 6av3B-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV3_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	6av3A-2vy0A: undetectable 6av3B-2vy0A: undetectable	6av3A-2vy0A: 15.73 6av3B-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV4_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.40A	6av4A-2vy0A: undetectable 6av4B-2vy0A: undetectable	6av4A-2vy0A: 15.73 6av4B-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV4_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	6av4A-2vy0A: undetectable 6av4B-2vy0A: undetectable	6av4A-2vy0A: 15.73 6av4B-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV5_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.42A	6av5A-2vy0A: undetectable 6av5B-2vy0A: undetectable	6av5A-2vy0A: 15.73 6av5B-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AV5_B_H4BB803_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.43A	6av5A-2vy0A: undetectable 6av5B-2vy0A: undetectable	6av5A-2vy0A: 15.73 6av5B-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CIC_A_H4BA802_0 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.44A	6cicA-2vy0A: undetectable 6cicB-2vy0A: undetectable	6cicA-2vy0A: 15.73 6cicB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CIC_B_H4BB802_0 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.41A	6cicA-2vy0A: undetectable 6cicB-2vy0A: undetectable	6cicA-2vy0A: 15.73 6cicB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CID_A_H4BA802_0 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	VAL A 245 TRP A 252 PHE A 254 GLU A 251	None None None MRD  A1301 (-4.3A)	1.41A	6cidA-2vy0A: undetectable 6cidB-2vy0A: undetectable	6cidA-2vy0A: 15.73 6cidB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CID_B_H4BB803_0 (NITRIC OXIDE SYNTHASE, BRAIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	TRP A 252 PHE A 254 GLU A 251 VAL A 245	None None MRD  A1301 (-4.3A) None	1.42A	6cidA-2vy0A: undetectable 6cidB-2vy0A: undetectable	6cidA-2vy0A: 15.73 6cidB-2vy0A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6J20_A_GBQA1201_1 (SUBSTANCE-P RECEPTOR,ENDOLYSIN)	2vy0	ENDO-BETA-1,3-GLUCAN ASE (Pyrococcus furiosus)	4 / 7	GLN A 244 GLU A 239 HIS A 238 VAL A 188	None	1.04A	6j20A-2vy0A: undetectable	6j20A-2vy0A: 20.09