SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vy2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 2vy2 PROTEIN LEAFY
(Arabidopsis
thaliana) 		4 / 6 LEU A 382
PHE A 367
TYR A 264
VAL A 366
 None
 1.26A 1ibgH-2vy2A:
undetectable		 1ibgH-2vy2A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 2vy2 PROTEIN LEAFY
(Arabidopsis
thaliana) 		5 / 12 CYH A 348
SER A 327
LEU A 257
VAL A 341
LEU A 373
 None
 1.33A 2prgB-2vy2A:
undetectable		 2prgB-2vy2A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_ACTA303_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 2vy2 PROTEIN LEAFY
(Arabidopsis
thaliana) 		3 / 3 TYR A 349
HIS A 312
ARG A 345
 None
 0.97A 4htfA-2vy2A:
undetectable		 4htfA-2vy2A:
20.71