SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vyi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 2vyi SGTA PROTEIN
(Homo
sapiens) 		4 / 7 ALA A 157
PRO A 156
TYR A 158
ALA A 125
 None
 1.12A 3twpA-2vyiA:
undetectable		 3twpA-2vyiA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 2vyi SGTA PROTEIN
(Homo
sapiens) 		4 / 7 ALA A 157
PRO A 156
TYR A 158
ALA A 125
 None
 1.10A 3twpB-2vyiA:
undetectable		 3twpB-2vyiA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 2vyi SGTA PROTEIN
(Homo
sapiens) 		4 / 7 ALA A 157
PRO A 156
TYR A 158
ALA A 125
 None
 1.10A 3twpC-2vyiA:
undetectable		 3twpC-2vyiA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 2vyi SGTA PROTEIN
(Homo
sapiens) 		4 / 5 ALA A 157
PRO A 156
TYR A 158
ALA A 125
 None
 1.09A 3twpD-2vyiA:
undetectable		 3twpD-2vyiA:
18.42