SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vyo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2vyo POLYSACCHARIDE
DEACETYLASE
DOMAIN-CONTAINING
PROTEIN ECU11_0510
(Encephalitozoon
cuniculi) 		3 / 3 ARG A 123
GLU A 121
THR A 120
 None
IMD  A1229 ( 4.7A)
None
 0.81A 3v4tA-2vyoA:
undetectable		 3v4tA-2vyoA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2vyo POLYSACCHARIDE
DEACETYLASE
DOMAIN-CONTAINING
PROTEIN ECU11_0510
(Encephalitozoon
cuniculi) 		5 / 11 ALA A  55
LEU A  48
PHE A 166
VAL A 163
TYR A 157
 None
 1.34A 4claA-2vyoA:
undetectable		 4claA-2vyoA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 2vyo POLYSACCHARIDE
DEACETYLASE
DOMAIN-CONTAINING
PROTEIN ECU11_0510
(Encephalitozoon
cuniculi) 		4 / 6 ARG A  86
GLY A  35
ALA A  84
GLN A 188
 None
 1.12A 4g0uA-2vyoA:
undetectable		 4g0uA-2vyoA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2vyo POLYSACCHARIDE
DEACETYLASE
DOMAIN-CONTAINING
PROTEIN ECU11_0510
(Encephalitozoon
cuniculi) 		4 / 8 VAL A  40
ARG A  43
VAL A  66
GLY A  67
 None
 1.03A 4mk4A-2vyoA:
undetectable		 4mk4A-2vyoA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2vyo POLYSACCHARIDE
DEACETYLASE
DOMAIN-CONTAINING
PROTEIN ECU11_0510
(Encephalitozoon
cuniculi) 		4 / 6 VAL A  53
LEU A  51
LEU A 195
PHE A  59
 None
 1.12A 4o1zA-2vyoA:
undetectable		 4o1zA-2vyoA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2vyo POLYSACCHARIDE
DEACETYLASE
DOMAIN-CONTAINING
PROTEIN ECU11_0510
(Encephalitozoon
cuniculi) 		4 / 8 PHE A  57
TYR A  73
PHE A  59
GLY A  39
 None
 0.98A 4qoiA-2vyoA:
undetectable
4qoiB-2vyoA:
undetectable		 4qoiA-2vyoA:
20.66
4qoiB-2vyoA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 2vyo POLYSACCHARIDE
DEACETYLASE
DOMAIN-CONTAINING
PROTEIN ECU11_0510
(Encephalitozoon
cuniculi) 		3 / 3 LEU A  85
VAL A  33
ASP A  34
 None
 0.48A 4y8wC-2vyoA:
undetectable		 4y8wC-2vyoA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NR3_A_95EA401_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3B)		 2vyo POLYSACCHARIDE
DEACETYLASE
DOMAIN-CONTAINING
PROTEIN ECU11_0510
(Encephalitozoon
cuniculi) 		4 / 7 ILE A  28
PHE A 180
LYS A 205
SER A 168
 None
 1.36A 5nr3A-2vyoA:
undetectable		 5nr3A-2vyoA:
21.22