SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vz5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 2vz5 TAX1-BINDING PROTEIN
3
(Homo
sapiens) 		4 / 8 ASP A  40
GLY A  34
SER A  47
ASP A  49
 None
 0.82A 1m4iA-2vz5A:
undetectable		 1m4iA-2vz5A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 2vz5 TAX1-BINDING PROTEIN
3
(Homo
sapiens) 		4 / 4 THR A  58
GLY A  36
ASP A  38
ALA A  93
 None
 1.13A 1sg9A-2vz5A:
undetectable		 1sg9A-2vz5A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 2vz5 TAX1-BINDING PROTEIN
3
(Homo
sapiens) 		5 / 9 LEU A 107
GLY A  70
ALA A  69
GLY A  64
ILE A  18
 None
 0.97A 3oxvC-2vz5A:
undetectable		 3oxvC-2vz5A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 2vz5 TAX1-BINDING PROTEIN
3
(Homo
sapiens) 		5 / 10 LEU A  97
VAL A  57
VAL A  16
ALA A  66
LEU A 107
 None
 1.12A 6czmA-2vz5A:
undetectable
6czmC-2vz5A:
undetectable		 6czmA-2vz5A:
18.42
6czmC-2vz5A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 2vz5 TAX1-BINDING PROTEIN
3
(Homo
sapiens) 		6 / 12 LEU A 107
GLY A  70
ALA A  69
GLY A  64
VAL A 105
ILE A  18
 None
 1.45A 6dilB-2vz5A:
undetectable		 6dilB-2vz5A:
20.28