SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vz9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 5 THR A1890
THR A1915
GLU A1958
THR A1957
 None
NAP  A3002 (-4.3A)
None
None
 1.42A 1d4fB-2vz9A:
undetectable		 1d4fB-2vz9A:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A1497
GLY A1499
LEU A1493
SER A1412
PRO A1413
 None
 0.94A 1dfoA-2vz9A:
undetectable		 1dfoA-2vz9A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A1497
GLY A1499
LEU A1493
SER A1412
PRO A1413
 None
 0.94A 1dfoB-2vz9A:
undetectable		 1dfoB-2vz9A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A1497
GLY A1499
LEU A1493
SER A1412
PRO A1413
 None
 0.94A 1dfoC-2vz9A:
undetectable		 1dfoC-2vz9A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A1497
GLY A1499
LEU A1493
SER A1412
PRO A1413
 None
 0.94A 1dfoD-2vz9A:
undetectable		 1dfoD-2vz9A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 8 ALA A 426
LEU A 423
LEU A 424
LEU A 438
ALA A 471
 None
 1.14A 1e7cA-2vz9A:
undetectable		 1e7cA-2vz9A:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A1497
GLY A1499
LEU A1493
SER A1412
PRO A1413
 None
 0.96A 1eqbA-2vz9A:
undetectable		 1eqbA-2vz9A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A1497
GLY A1499
LEU A1493
SER A1412
PRO A1413
 None
 0.96A 1eqbB-2vz9A:
undetectable		 1eqbB-2vz9A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A1497
GLY A1499
LEU A1493
SER A1412
PRO A1413
 None
 0.95A 1eqbC-2vz9A:
undetectable		 1eqbC-2vz9A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A1497
GLY A1499
LEU A1493
SER A1412
PRO A1413
 None
 0.95A 1eqbD-2vz9A:
undetectable		 1eqbD-2vz9A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 10 THR A1122
PRO A1123
GLY A1512
PHE A1517
THR A1232
 None
 1.36A 1h4oA-2vz9A:
undetectable
1h4oB-2vz9A:
undetectable		 1h4oA-2vz9A:
6.45
1h4oB-2vz9A:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_D_BEZD1162_0
(PEROXIREDOXIN 5)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 9 THR A1122
PRO A1123
GLY A1512
PHE A1517
THR A1232
 None
 1.30A 1h4oD-2vz9A:
undetectable		 1h4oD-2vz9A:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_E_BEZE1162_0
(PEROXIREDOXIN 5)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 9 THR A1122
PRO A1123
GLY A1512
PHE A1517
THR A1232
 None
 1.31A 1h4oE-2vz9A:
undetectable
1h4oF-2vz9A:
undetectable		 1h4oE-2vz9A:
6.45
1h4oF-2vz9A:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_F_BEZF1162_0
(PEROXIREDOXIN 5)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 9 THR A1122
PRO A1123
GLY A1512
PHE A1517
THR A1232
 None
 1.33A 1h4oF-2vz9A:
undetectable		 1h4oF-2vz9A:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_H_BEZH1162_0
(PEROXIREDOXIN 5)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 9 THR A1122
PRO A1123
GLY A1512
PHE A1517
THR A1232
 None
 1.32A 1h4oH-2vz9A:
undetectable		 1h4oH-2vz9A:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HD2_A_BEZA201_0
(PEROXIREDOXIN 5
RESIDUES 54-214)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 9 THR A1122
PRO A1123
GLY A1512
PHE A1517
THR A1232
 None
 1.30A 1hd2A-2vz9A:
undetectable		 1hd2A-2vz9A:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 8 LEU A 521
SER A 555
ASP A 536
THR A 541
 None
 1.12A 1ig3A-2vz9A:
undetectable
1ig3B-2vz9A:
undetectable		 1ig3A-2vz9A:
7.48
1ig3B-2vz9A:
7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 GLY A 330
VAL A  33
ASP A  31
ALA A 340
SER A 336
 None
 1.31A 1kiaD-2vz9A:
undetectable		 1kiaD-2vz9A:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 ARG A1934
ARG A1084
ARG A1930
 None
 0.87A 1l7fA-2vz9A:
undetectable		 1l7fA-2vz9A:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 ARG A1934
ARG A1084
ARG A1930
 None
 0.87A 1l7hA-2vz9A:
undetectable		 1l7hA-2vz9A:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 GLY A 330
VAL A  33
ASP A  31
ALA A 340
SER A 336
 None
 1.34A 1nbhC-2vz9A:
undetectable		 1nbhC-2vz9A:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 5 ASP A1251
ASP A1276
LEU A1282
LEU A1321
 None
 1.14A 1nh8A-2vz9A:
undetectable		 1nh8A-2vz9A:
8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 8 THR A1122
PRO A1123
GLY A1512
PHE A1517
THR A1232
 None
 1.36A 1oc3A-2vz9A:
undetectable		 1oc3A-2vz9A:
6.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_B_BEZB201_0
(PEROXIREDOXIN 5)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 9 THR A1122
PRO A1123
GLY A1512
PHE A1517
THR A1232
 None
 1.32A 1oc3B-2vz9A:
undetectable		 1oc3B-2vz9A:
6.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 7 THR A 923
VAL A 931
VAL A 884
ILE A 924
 None
 0.99A 1p7rA-2vz9A:
undetectable		 1p7rA-2vz9A:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 10 LEU A1796
VAL A1651
ALA A1655
SER A1658
LEU A1659
 NAP  A3001 (-3.9A)
None
None
None
None
 1.06A 1pxxA-2vz9A:
undetectable		 1pxxA-2vz9A:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_C_DIFC2701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A1796
VAL A1651
ALA A1655
SER A1658
LEU A1659
 NAP  A3001 (-3.9A)
None
None
None
None
 1.06A 1pxxC-2vz9A:
undetectable		 1pxxC-2vz9A:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SS4_A_ACTA411_0
(GLYOXALASE FAMILY
PROTEIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 5 VAL A 400
THR A 251
GLN A 169
ILE A 157
 None
 1.35A 1ss4A-2vz9A:
undetectable		 1ss4A-2vz9A:
5.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 4 SER A1056
ILE A1057
VAL A1089
THR A 972
 None
 1.21A 1u70A-2vz9A:
undetectable		 1u70A-2vz9A:
6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPO_H_TESH1010_1
(ANTI-TESTOSTERONE
(HEAVY CHAIN)
ANTI-TESTOSTERONE
(LIGHT CHAIN))		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 SER A1039
TYR A1049
GLY A1098
PHE A1054
PRO A1051
 None
 1.23A 1vpoH-2vz9A:
undetectable
1vpoL-2vz9A:
undetectable		 1vpoH-2vz9A:
6.02
1vpoL-2vz9A:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A1876
GLY A1875
HIS A1530
THR A1624
ILE A1871
 None
 1.26A 1z95A-2vz9A:
undetectable		 1z95A-2vz9A:
7.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 GLY A   8
VAL A 184
ALA A 230
ASP A  92
ALA A  89
 None
 1.37A 2avdB-2vz9A:
undetectable		 2avdB-2vz9A:
7.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_B_DVAB35_0
(UBIQUITIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 6 ARG A1857
LEU A1868
ILE A1871
PRO A1870
 None
 0.96A 2fcnA-2vz9A:
undetectable
2fcnB-2vz9A:
undetectable		 2fcnA-2vz9A:
2.56
2fcnB-2vz9A:
2.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 ASN A 189
TYR A 222
SER A 336
 None
 0.64A 2gvcB-2vz9A:
undetectable		 2gvcB-2vz9A:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 ASN A 189
TYR A 222
SER A 336
 None
 0.59A 2gvcE-2vz9A:
undetectable		 2gvcE-2vz9A:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 8 LEU A1041
LEU A 987
ASP A1014
ARG A1927
 None
 1.08A 2j2pA-2vz9A:
undetectable
2j2pB-2vz9A:
undetectable		 2j2pA-2vz9A:
5.91
2j2pB-2vz9A:
5.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 ARG A1439
ARG A1468
ARG A1470
 None
 0.98A 2jb7A-2vz9A:
undetectable
2jb7B-2vz9A:
undetectable
2jb7C-2vz9A:
undetectable		 2jb7A-2vz9A:
5.44
2jb7B-2vz9A:
5.44
2jb7C-2vz9A:
5.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A1022
ILE A1057
SER A1013
LEU A1041
VAL A 992
 None
 1.17A 2po7A-2vz9A:
undetectable		 2po7A-2vz9A:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A1022
ILE A1057
SER A1013
LEU A1041
VAL A 992
 None
 1.14A 2po7B-2vz9A:
undetectable		 2po7B-2vz9A:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 7 LEU A  82
VAL A  85
THR A  86
VAL A 338
 None
 0.92A 2qblA-2vz9A:
undetectable		 2qblA-2vz9A:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 5 PHE A 553
SER A 714
PHE A 682
ILE A 717
 None
 1.22A 2v0mD-2vz9A:
undetectable		 2v0mD-2vz9A:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 8 ILE A 549
ARG A 606
LEU A 582
PHE A 682
 None
 0.89A 2vctC-2vz9A:
undetectable		 2vctC-2vz9A:
6.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 10 THR A1122
PRO A1123
GLY A1512
PHE A1517
THR A1232
 None
 1.38A 2vl2A-2vz9A:
undetectable
2vl2C-2vz9A:
undetectable		 2vl2A-2vz9A:
6.03
2vl2C-2vz9A:
6.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 ARG A 728
ARG A 708
PRO A 707
 None
 0.94A 2wljA-2vz9A:
undetectable		 2wljA-2vz9A:
7.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 10 VAL A 912
ILE A1059
LEU A 919
LEU A1032
GLY A 890
 None
 1.12A 2xf3A-2vz9A:
undetectable		 2xf3A-2vz9A:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 8 ASN A2001
GLY A1951
SER A1944
THR A1890
 None
 0.86A 2yoeB-2vz9A:
undetectable
2yoeC-2vz9A:
undetectable		 2yoeB-2vz9A:
7.86
2yoeC-2vz9A:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 GLY A 807
PRO A 462
ILE A 782
VAL A 800
LEU A 572
 None
 1.22A 2zzmA-2vz9A:
undetectable		 2zzmA-2vz9A:
8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 8 VAL A1245
THR A1275
GLY A1250
ALA A1249
 None
 0.72A 3aruA-2vz9A:
undetectable		 3aruA-2vz9A:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 TRP A1592
VAL A1547
ARG A1523
 None
 0.95A 3b0wA-2vz9A:
undetectable		 3b0wA-2vz9A:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 4 THR A1922
VAL A1929
GLY A1892
THR A1890
 None
 1.10A 3cflA-2vz9A:
undetectable		 3cflA-2vz9A:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_K_SAMK302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 GLY A 389
LEU A 247
ASN A 387
LEU A 287
LEU A 320
 None
 1.30A 3cjtK-2vz9A:
undetectable		 3cjtK-2vz9A:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 8 MET A 140
ALA A 141
LEU A 144
ILE A 342
 None
 0.83A 3cldB-2vz9A:
undetectable		 3cldB-2vz9A:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 GLY A 498
GLY A 500
PHE A 553
SER A 552
SER A 581
 None
 1.39A 3dlcA-2vz9A:
undetectable		 3dlcA-2vz9A:
6.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_1
(PROTEASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 11 LEU A 567
ALA A 590
ILE A 561
GLY A 583
ILE A 564
 None
 0.91A 3ebzA-2vz9A:
undetectable		 3ebzA-2vz9A:
3.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 HIS A 401
LEU A 168
VAL A 231
ILE A 342
TYR A 277
 None
 1.28A 3g9eA-2vz9A:
undetectable		 3g9eA-2vz9A:
7.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_B_DEXB247_1
(GLUCOCORTICOID
RECEPTOR 2)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A1748
ASN A1746
GLY A1770
VAL A1744
PHE A1766
 None
 1.45A 3gn8B-2vz9A:
undetectable		 3gn8B-2vz9A:
7.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 5 LEU A2056
LYS A1118
GLN A2059
LEU A2106
 None
 1.12A 3h5gA-2vz9A:
undetectable
3h5gB-2vz9A:
undetectable		 3h5gA-2vz9A:
1.19
3h5gB-2vz9A:
1.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_C_TMQC613_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 11 VAL A 402
ILE A 175
LEU A 233
ILE A 246
THR A 251
 None
 1.07A 3hbbC-2vz9A:
undetectable		 3hbbC-2vz9A:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 10 ILE A1685
SER A1675
GLY A1676
SER A1723
LEU A1715
 None
NAP  A3001 (-3.5A)
None
NAP  A3001 (-2.9A)
None
 1.37A 3ik6B-2vz9A:
undetectable
3ik6E-2vz9A:
undetectable		 3ik6B-2vz9A:
7.05
3ik6E-2vz9A:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_A_KANA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 11 ALA A 732
GLU A 733
SER A 735
ASN A 738
ARG A 606
 None
 1.41A 3kp5A-2vz9A:
undetectable		 3kp5A-2vz9A:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA270_0
(PROTEIN SSM1)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 5 LEU A1140
SER A1218
LEU A1355
PRO A1354
 None
 1.22A 3onnA-2vz9A:
undetectable		 3onnA-2vz9A:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_2
(HIV-1 PROTEASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 11 LEU A 567
ALA A 590
ASP A 591
GLY A 579
ILE A 564
 None
 1.23A 3oxxB-2vz9A:
undetectable		 3oxxB-2vz9A:
3.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 THR A1697
GLY A1681
ALA A1684
ALA A1688
LEU A1659
 None
 1.08A 3p5nA-2vz9A:
undetectable		 3p5nA-2vz9A:
6.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPS_A_CHDA211_0
(CMER)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 10 LEU A1032
ALA A1091
GLY A1093
ILE A1059
PHE A1054
 None
 1.35A 3qpsA-2vz9A:
undetectable		 3qpsA-2vz9A:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_A_EVPA1_1
(DNA TOPOISOMERASE
2-BETA)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 5 GLY A1000
ASP A1002
ARG A 997
GLN A2086
 None
 1.37A 3qx3A-2vz9A:
undetectable		 3qx3A-2vz9A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 6 ASP A1214
LEU A1211
LEU A1362
THR A1363
 None
 0.83A 3rozA-2vz9A:
undetectable		 3rozA-2vz9A:
7.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 PHE A1880
GLN A1910
PHE A1532
 None
 0.85A 3rv5A-2vz9A:
undetectable		 3rv5A-2vz9A:
2.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_1
(HIV-1 PROTEASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		6 / 10 ALA A 590
ASP A 591
GLY A 579
ILE A 495
LEU A 563
ILE A 564
 None
 1.15A 3ttpA-2vz9A:
undetectable		 3ttpA-2vz9A:
3.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_2
(HIV-1 PROTEASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		6 / 10 ALA A 590
ASP A 591
GLY A 579
ILE A 495
LEU A 563
ILE A 564
 None
 1.12A 3ttpB-2vz9A:
undetectable		 3ttpB-2vz9A:
3.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 11 MET A   9
GLY A  93
ASP A  92
SER A 831
LEU A 346
 None
 1.24A 3v8vB-2vz9A:
undetectable		 3v8vB-2vz9A:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VM4_A_IZPA1_1
(FATTY ACID
ALPHA-HYDROXYLASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 5 LEU A1216
ARG A1182
PRO A1181
ALA A1186
 None
 1.47A 3vm4A-2vz9A:
undetectable		 3vm4A-2vz9A:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 ARG A1468
ARG A1405
ASP A1313
 None
 1.02A 3wipG-2vz9A:
undetectable
3wipH-2vz9A:
undetectable		 3wipG-2vz9A:
6.81
3wipH-2vz9A:
6.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 GLN A 259
ASP A 254
GLN A 269
 None
 0.91A 4aztA-2vz9A:
undetectable		 4aztA-2vz9A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9W_A_VGHA1158_1
(7,8-DIHYDRO-8-OXOGUA
NINE TRIPHOSPHATASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 PHE A2036
PHE A1988
MET A1456
VAL A1453
PHE A1423
 None
 1.48A 4c9wA-2vz9A:
undetectable		 4c9wA-2vz9A:
5.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 LEU A1748
GLU A1751
SER A1756
 None
 0.84A 4ccqA-2vz9A:
undetectable		 4ccqA-2vz9A:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 MET A1503
LEU A1980
GLY A2035
SER A2039
ARG A2043
 None
 1.39A 4djfB-2vz9A:
undetectable		 4djfB-2vz9A:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 5 PHE A 553
PHE A 682
ILE A 549
GLY A 678
 None
 1.03A 4ejjC-2vz9A:
undetectable		 4ejjC-2vz9A:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG1_A_ACTA504_0
(FAD:PROTEIN FMN
TRANSFERASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 5 SER A 569
ARG A 515
LEU A 566
ASP A 565
 None
 1.48A 4ig1A-2vz9A:
undetectable		 4ig1A-2vz9A:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 8 ASN A 328
ASP A 301
ASN A 356
ILE A 322
 None
 1.01A 4k0bA-2vz9A:
undetectable		 4k0bA-2vz9A:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 ARG A  59
ASP A 843
ASP A 849
 None
 0.90A 4kicB-2vz9A:
undetectable		 4kicB-2vz9A:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 LEU A 320
PRO A 319
ARG A 274
 None
 0.75A 4klrB-2vz9A:
undetectable		 4klrB-2vz9A:
9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 GLY A1455
ASN A1458
MET A1456
ARG A1507
LEU A1477
 None
 1.30A 4kovA-2vz9A:
undetectable		 4kovA-2vz9A:
4.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOX_A_CLSA205_1
(UNCHARACTERIZED
PROTEIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 11 GLY A1455
ASN A1458
MET A1456
ARG A1507
LEU A1477
 None
 1.30A 4koxA-2vz9A:
undetectable		 4koxA-2vz9A:
4.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 8 ASN A 328
ASP A 301
ASN A 356
ILE A 322
 None
 0.98A 4l7iA-2vz9A:
undetectable		 4l7iA-2vz9A:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		7 / 12 ALA A 160
CYH A 161
PHE A 200
HIS A 293
THR A 295
HIS A 331
GLY A 394
 None
 0.49A 4ls7A-2vz9A:
undetectable		 4ls7A-2vz9A:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		6 / 12 CYH A 161
PHE A 200
HIS A 293
HIS A 331
GLY A 394
PHE A 395
 None
 1.07A 4ls7A-2vz9A:
undetectable		 4ls7A-2vz9A:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		7 / 12 ALA A 160
CYH A 161
PHE A 200
HIS A 293
THR A 295
HIS A 331
GLY A 394
 None
 0.46A 4ls7A-2vz9A:
undetectable
4ls7B-2vz9A:
undetectable		 4ls7A-2vz9A:
10.13
4ls7B-2vz9A:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		6 / 12 CYH A 161
PHE A 200
HIS A 293
HIS A 331
GLY A 394
PHE A 395
 None
 1.09A 4ls7A-2vz9A:
undetectable
4ls7B-2vz9A:
undetectable		 4ls7A-2vz9A:
10.13
4ls7B-2vz9A:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 8 PHE A1514
ARG A1515
SER A2039
SER A1475
 None
 1.08A 4lv9A-2vz9A:
undetectable
4lv9B-2vz9A:
undetectable		 4lv9A-2vz9A:
11.32
4lv9B-2vz9A:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A1226
GLY A1128
ALA A1225
LEU A1401
GLY A1132
 None
 0.90A 4n09C-2vz9A:
undetectable		 4n09C-2vz9A:
8.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 HIS A 401
LEU A 168
VAL A 231
MET A   9
TYR A 277
 None
 1.39A 4o8fB-2vz9A:
undetectable		 4o8fB-2vz9A:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 ALA A 160
GLN A 269
GLY A 266
 None
 0.54A 4odoC-2vz9A:
undetectable		 4odoC-2vz9A:
5.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A 797
LEU A 793
LEU A 563
ILE A 782
VAL A 759
 None
 1.05A 4ok1A-2vz9A:
undetectable		 4ok1A-2vz9A:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A1876
GLY A1875
HIS A1530
THR A1624
ILE A1871
 None
 1.25A 4okbA-2vz9A:
undetectable		 4okbA-2vz9A:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A1876
GLY A1875
HIS A1530
THR A1624
ILE A1871
 None
 1.23A 4okwA-2vz9A:
undetectable		 4okwA-2vz9A:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 11 LEU A1401
SER A1399
LEU A1220
LEU A1345
LEU A1221
 None
 1.45A 4or0A-2vz9A:
undetectable		 4or0A-2vz9A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 SER A 569
LEU A 797
PHE A 796
PHE A 816
GLY A 814
 None
 1.41A 4pevC-2vz9A:
undetectable		 4pevC-2vz9A:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 6 THR A1890
THR A1915
THR A1957
LEU A2002
 None
NAP  A3002 (-4.3A)
None
None
 1.14A 4pgfA-2vz9A:
undetectable		 4pgfA-2vz9A:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 GLY A2025
ASN A1458
SER A2108
ASN A2028
THR A2083
 None
 1.32A 4pooA-2vz9A:
undetectable		 4pooA-2vz9A:
7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 ILE A 880
ASP A1033
ARG A 999
 None
 0.84A 4pstA-2vz9A:
undetectable		 4pstA-2vz9A:
5.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 PHE A1712
THR A1654
LEU A1826
 None
NAP  A3001 (-3.0A)
None
 0.67A 4qztA-2vz9A:
undetectable		 4qztA-2vz9A:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 ARG A 274
GLN A 271
GLU A 270
 None
 0.87A 4tvtA-2vz9A:
undetectable		 4tvtA-2vz9A:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 ALA A1531
TRP A1546
VAL A1547
 None
 0.41A 4w9nC-2vz9A:
undetectable		 4w9nC-2vz9A:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 6 THR A 898
SER A 947
TYR A 862
LEU A 933
 None
 1.05A 4wozA-2vz9A:
undetectable
4wozB-2vz9A:
undetectable		 4wozA-2vz9A:
8.54
4wozB-2vz9A:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_B_LOCB502_1
(TUBULIN BETA CHAIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A1022
ALA A1034
LEU A1032
ALA A1094
ILE A1059
 None
 1.05A 4x20B-2vz9A:
undetectable		 4x20B-2vz9A:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA406_0
(FAD:PROTEIN FMN
TRANSFERASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 5 SER A 569
ARG A 515
LEU A 566
ASP A 565
 None
 1.18A 4xdtA-2vz9A:
undetectable		 4xdtA-2vz9A:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 5 LEU A  82
ALA A  89
VAL A 338
ILE A 342
 None
 0.92A 4xe3B-2vz9A:
undetectable		 4xe3B-2vz9A:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 ALA A 335
GLY A 187
SER A 164
LEU A  83
GLU A  84
 None
 1.08A 5c0oH-2vz9A:
undetectable		 5c0oH-2vz9A:
7.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 11 VAL A 670
VAL A 672
ILE A 638
ILE A 651
LEU A 625
 None
 0.95A 5e4dB-2vz9A:
undetectable		 5e4dB-2vz9A:
5.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 GLY A1897
GLY A2064
GLY A2067
GLU A2071
ASP A2077
 None
None
NAP  A3002 (-3.3A)
None
None
 0.83A 5e9qC-2vz9A:
undetectable		 5e9qC-2vz9A:
7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 6 ILE A   6
ALA A 183
VAL A 185
VAL A   4
 None
 0.89A 5eclD-2vz9A:
undetectable		 5eclD-2vz9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 GLY A1897
GLY A2064
GLY A2067
GLU A2071
ASP A2077
 None
None
NAP  A3002 (-3.3A)
None
None
 0.83A 5eifC-2vz9A:
undetectable		 5eifC-2vz9A:
7.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESE_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 8 LEU A 272
ILE A 308
GLY A 389
LEU A 165
 None
 0.70A 5eseA-2vz9A:
undetectable		 5eseA-2vz9A:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A1689
PHE A1712
ILE A1818
ALA A1655
LEU A1814
 None
 1.16A 5ienA-2vz9A:
undetectable		 5ienA-2vz9A:
4.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 VAL A1636
SER A1647
MET A1601
 None
 0.93A 5ikqA-2vz9A:
undetectable		 5ikqA-2vz9A:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 GLY A1963
GLN A1961
LYS A1911
 None
 0.91A 5imsB-2vz9A:
undetectable		 5imsB-2vz9A:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A1022
ALA A1034
LEU A1032
ALA A1094
ILE A1059
 None
 1.05A 5itzB-2vz9A:
undetectable		 5itzB-2vz9A:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 7 GLY A1356
GLY A1398
SER A1395
PHE A1396
 None
 0.82A 5izfA-2vz9A:
undetectable		 5izfA-2vz9A:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 PRO A1043
ARG A1084
GLU A1016
 None
 0.96A 5j6hA-2vz9A:
undetectable		 5j6hA-2vz9A:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 4 PHE A1712
ILE A1685
GLN A1824
ARG A1711
 None
 1.38A 5jm4B-2vz9A:
undetectable		 5jm4B-2vz9A:
6.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 ARG A1934
PRO A1043
ASN A1018
 None
 0.89A 5jwaA-2vz9A:
undetectable
5jwaH-2vz9A:
undetectable		 5jwaA-2vz9A:
11.04
5jwaH-2vz9A:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_2
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 VAL A 388
ARG A 379
PRO A 355
 None
 0.86A 5koxA-2vz9A:
undetectable		 5koxA-2vz9A:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 5 PHE A 553
SER A 603
GLN A 502
ASP A 542
 None
 1.32A 5kpcA-2vz9A:
undetectable		 5kpcA-2vz9A:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 ASP A 123
GLU A 125
LEU A 925
ARG A 901
LEU A 894
 None
 1.17A 5m50E-2vz9A:
undetectable		 5m50E-2vz9A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		6 / 12 VAL A1648
ILE A1769
ILE A1687
LEU A1659
ILE A1673
PHE A1712
 None
NAP  A3001 (-4.1A)
None
None
None
None
 1.36A 5mueA-2vz9A:
undetectable		 5mueA-2vz9A:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 GLY A1897
GLY A2064
GLY A2067
GLU A2071
ASP A2077
 None
None
NAP  A3002 (-3.3A)
None
None
 0.94A 5njvD-2vz9A:
undetectable		 5njvD-2vz9A:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 GLY A1700
THR A1698
ASN A1722
 NAP  A3001 (-4.0A)
None
None
 0.60A 5odiG-2vz9A:
undetectable		 5odiG-2vz9A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 LYS A 326
HIS A 293
HIS A 331
 None
 1.37A 5oexA-2vz9A:
undetectable		 5oexA-2vz9A:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 LYS A 326
HIS A 293
HIS A 331
 None
 1.43A 5oexB-2vz9A:
undetectable		 5oexB-2vz9A:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 LYS A 326
HIS A 293
HIS A 331
 None
 1.37A 5oexC-2vz9A:
undetectable		 5oexC-2vz9A:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 LYS A 326
HIS A 293
HIS A 331
 None
 1.34A 5oexD-2vz9A:
undetectable		 5oexD-2vz9A:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 9 GLY A   8
LEU A 232
ILE A  95
GLY A  94
PHE A 147
 None
 0.92A 5vkqC-2vz9A:
undetectable
5vkqD-2vz9A:
undetectable		 5vkqC-2vz9A:
22.62
5vkqD-2vz9A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 8 GLN A 560
GLY A 498
GLU A 584
ILE A 495
 None
 1.02A 5vlmD-2vz9A:
undetectable		 5vlmD-2vz9A:
5.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 GLY A1897
GLY A2064
GLY A2067
GLU A2071
ASP A2077
 None
None
NAP  A3002 (-3.3A)
None
None
 0.91A 5wz1B-2vz9A:
undetectable		 5wz1B-2vz9A:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_1
(CYTOCHROME P450 2C9)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 ALA A  89
VAL A 184
GLY A 187
ALA A 335
LEU A  13
 None
 1.20A 5x23A-2vz9A:
undetectable		 5x23A-2vz9A:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 GLU A 908
TRP A 896
HIS A1064
 None
 0.91A 5xipA-2vz9A:
undetectable		 5xipA-2vz9A:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 LEU A1022
ALA A1034
LEU A1032
ALA A1094
ILE A1059
 None
 1.02A 5xiwB-2vz9A:
undetectable		 5xiwB-2vz9A:
2.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_0
(CARNOSINE
N-METHYLTRANSFERASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 GLY A1897
GLY A1894
TRP A2060
PHE A1969
TYR A1924
 None
NAP  A3002 (-3.3A)
None
None
None
 1.39A 5yf0A-2vz9A:
undetectable		 5yf0A-2vz9A:
8.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 GLY A 300
GLY A 219
ASP A 254
ASP A 301
PHE A 393
 None
 1.33A 5yn6A-2vz9A:
undetectable		 5yn6A-2vz9A:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 TYR A 993
LEU A1011
ASP A1073
 None
 0.77A 5zv2B-2vz9A:
undetectable		 5zv2B-2vz9A:
2.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		5 / 12 ASP A2003
LEU A1900
LEU A1971
GLY A2055
LEU A2056
 None
None
NAP  A3002 (-4.7A)
None
None
 1.15A 6b0lB-2vz9A:
undetectable		 6b0lB-2vz9A:
2.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 7 LEU A1216
ALA A1186
GLN A1189
GLN A1253
 None
 1.18A 6b89A-2vz9A:
undetectable		 6b89A-2vz9A:
2.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_2
(PROTEASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		3 / 3 GLY A  94
ASP A  92
ILE A 834
 None
 0.60A 6dgxB-2vz9A:
undetectable		 6dgxB-2vz9A:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 6 GLN A1494
LEU A1493
SER A1489
PHE A1415
 None
 1.03A 6ekuA-2vz9A:
undetectable		 6ekuA-2vz9A:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 8 ASP A  92
SER A 831
TYR A 243
GLY A 351
 None
 0.84A 6giqL-2vz9A:
undetectable
6giqP-2vz9A:
undetectable
6giqT-2vz9A:
undetectable		 6giqL-2vz9A:
11.12
6giqP-2vz9A:
6.45
6giqT-2vz9A:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_H_PCFH604_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 8 GLY A2027
VAL A1454
GLY A2061
SER A2021
 None
None
None
NAP  A3002 (-3.4A)
 0.80A 6hu9H-2vz9A:
undetectable
6hu9e-2vz9A:
undetectable		 6hu9H-2vz9A:
3.08
6hu9e-2vz9A:
4.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 4 ASP A1231
ILE A1258
PRO A1259
LEU A1262
 None
 1.39A 6mkeB-2vz9A:
undetectable		 6mkeB-2vz9A:
2.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 4 ASP A1231
ILE A1258
PRO A1259
LEU A1262
 None
 1.44A 6mkeA-2vz9A:
undetectable		 6mkeA-2vz9A:
2.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 2vz9 FATTY ACID SYNTHASE
(Sus
scrofa) 		4 / 7 GLY A 394
HIS A 401
ASN A 391
GLY A 337
 None
 0.97A 6n7fA-2vz9A:
undetectable		 6n7fA-2vz9A:
2.92