SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vzn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 2vzn VENOM ALLERGEN 3
(Solenopsis
invicta) 		3 / 3 ALA A 116
VAL A 193
TRP A  92
 None
 0.78A 1c4dC-2vznA:
undetectable
1c4dD-2vznA:
undetectable		 1c4dC-2vznA:
7.46
1c4dD-2vznA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 2vzn VENOM ALLERGEN 3
(Solenopsis
invicta) 		3 / 3 TRP A  92
ALA A 116
VAL A 193
 None
 0.66A 1c4dC-2vznA:
undetectable
1c4dD-2vznA:
undetectable		 1c4dC-2vznA:
7.46
1c4dD-2vznA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2vzn VENOM ALLERGEN 3
(Solenopsis
invicta) 		4 / 7 GLY A 122
HIS A 190
THR A 188
SER A  34
 None
 0.89A 1gtfL-2vznA:
undetectable
1gtfM-2vznA:
undetectable		 1gtfL-2vznA:
18.46
1gtfM-2vznA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2vzn VENOM ALLERGEN 3
(Solenopsis
invicta) 		4 / 8 GLY A 122
HIS A 190
THR A 188
SER A  34
 None
 0.89A 1gtfN-2vznA:
undetectable
1gtfO-2vznA:
undetectable		 1gtfN-2vznA:
18.46
1gtfO-2vznA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 2vzn VENOM ALLERGEN 3
(Solenopsis
invicta) 		3 / 3 ALA A 116
VAL A 193
TRP A  92
 None
 0.86A 1tkqB-2vznA:
undetectable		 1tkqB-2vznA:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 2vzn VENOM ALLERGEN 3
(Solenopsis
invicta) 		3 / 3 MET A 131
ASN A  35
GLN A  90
 None
 0.81A 1xoqB-2vznA:
undetectable		 1xoqB-2vznA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2vzn VENOM ALLERGEN 3
(Solenopsis
invicta) 		4 / 5 GLU A  62
PHE A 142
TYR A 136
HIS A  50
 None
 1.43A 4a97J-2vznA:
undetectable		 4a97J-2vznA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 2vzn VENOM ALLERGEN 3
(Solenopsis
invicta) 		4 / 7 GLY A 161
TYR A 196
ASN A 201
HIS A 162
 None
 1.16A 4ws0A-2vznA:
undetectable		 4ws0A-2vznA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vzn VENOM ALLERGEN 3
(Solenopsis
invicta) 		4 / 8 SER A  34
GLY A 122
HIS A 190
THR A 188
 None
 0.88A 5eezL-2vznA:
undetectable
5eezV-2vznA:
undetectable		 5eezL-2vznA:
18.46
5eezV-2vznA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vzn VENOM ALLERGEN 3
(Solenopsis
invicta) 		4 / 8 SER A  34
GLY A 122
HIS A 190
THR A 188
 None
 0.88A 5ef1L-2vznA:
undetectable
5ef1V-2vznA:
undetectable		 5ef1L-2vznA:
18.46
5ef1V-2vznA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vzn VENOM ALLERGEN 3
(Solenopsis
invicta) 		4 / 8 SER A  34
GLY A 122
HIS A 190
THR A 188
 None
 0.89A 5ef2L-2vznA:
undetectable
5ef2V-2vznA:
undetectable		 5ef2L-2vznA:
18.46
5ef2V-2vznA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 2vzn VENOM ALLERGEN 3
(Solenopsis
invicta) 		4 / 5 ILE A 147
LEU A 203
GLY A 204
PHE A 150
 None
 0.82A 5kmdC-2vznA:
undetectable
5kmdD-2vznA:
undetectable		 5kmdC-2vznA:
18.82
5kmdD-2vznA:
18.82