SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2w0c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 2w0c PROTEIN 2
(Pseudoalteromona
s
virus
PM2) 		4 / 5 ASP L 224
VAL L 223
SER L 220
ASP L 306
 None
 1.24A 1n2xB-2w0cL:
undetectable		 1n2xB-2w0cL:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 2w0c PROTEIN 2
(Pseudoalteromona
s
virus
PM2) 		3 / 3 PRO L 236
PHE L 238
ALA L 214
 None
 0.53A 3itaD-2w0cL:
undetectable		 3itaD-2w0cL:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 2w0c PROTEIN 2
(Pseudoalteromona
s
virus
PM2) 		4 / 6 PRO L 236
TYR L 174
VAL L 315
THR L 310
 None
 1.10A 3tneA-2w0cL:
undetectable		 3tneA-2w0cL:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 2w0c PROTEIN 2
(Pseudoalteromona
s
virus
PM2) 		4 / 5 VAL L 300
VAL L 223
GLY L 222
PHE L 309
 None
 1.04A 5d4nA-2w0cL:
undetectable
5d4nC-2w0cL:
undetectable		 5d4nA-2w0cL:
16.22
5d4nC-2w0cL:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2w0c PROTEIN 2
(Pseudoalteromona
s
virus
PM2) 		4 / 5 LEU L 189
PHE L 196
PHE L 286
LEU L 250
 None
 1.13A 5x1bP-2w0cL:
undetectable		 5x1bP-2w0cL:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 2w0c PROTEIN 2
(Pseudoalteromona
s
virus
PM2) 		4 / 6 TYR L  74
ILE L  72
GLU L  71
ARG L  34
 None
 1.06A 5z3jA-2w0cL:
undetectable		 5z3jA-2w0cL:
21.57