SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2w0p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 2w0p FILAMIN-A
(Homo
sapiens) 		5 / 12 ILE A2261
GLY A2269
GLY A2270
ASN A2312
GLY A2237
 None
 0.82A 3uq6A-2w0pA:
undetectable		 3uq6A-2w0pA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 2w0p FILAMIN-A
(Homo
sapiens) 		4 / 8 HIS A2315
PRO A2320
LYS A2310
ALA A2272
 None
 0.95A 4k0bB-2w0pA:
undetectable		 4k0bB-2w0pA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 2w0p FILAMIN-A
(Homo
sapiens) 		4 / 8 HIS A2315
PRO A2320
LYS A2310
ALA A2272
 None
 0.96A 4l7iB-2w0pA:
undetectable		 4l7iB-2w0pA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_A_BEZA1001_0
(BENZOATE-COENZYME A
LIGASE)		 2w0p FILAMIN-A
(Homo
sapiens) 		5 / 8 ALA A2266
VAL A2241
GLY A2267
ALA A2268
GLY A2269
 None
 1.28A 4zjzA-2w0pA:
undetectable		 4zjzA-2w0pA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 2w0p FILAMIN-A
(Homo
sapiens) 		5 / 8 ALA A2266
VAL A2241
GLY A2267
ALA A2268
GLY A2269
 None
 1.31A 4zjzB-2w0pA:
undetectable		 4zjzB-2w0pA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2w0p FILAMIN-A
(Homo
sapiens) 		4 / 7 ALA A2266
ASP A2290
ARG A2288
GLU A2286
 None
 0.78A 5btgA-2w0pA:
undetectable
5btgC-2w0pA:
undetectable
5btgD-2w0pA:
undetectable		 5btgA-2w0pA:
12.02
5btgC-2w0pA:
12.02
5btgD-2w0pA:
14.52