SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2w1q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4001_1
(SERUM ALBUMIN)		 2w1q HYALURONOGLUCOSAMINI
DASE
(Clostridium
perfringens) 		4 / 5 ARG A 865
ALA A 942
ASP A 831
GLY A 829
 None
 1.14A 1e7bA-2w1qA:
undetectable		 1e7bA-2w1qA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 2w1q HYALURONOGLUCOSAMINI
DASE
(Clostridium
perfringens) 		4 / 8 ASN A 928
ARG A 925
LEU A 936
SER A 813
 None
 0.96A 1hk3A-2w1qA:
undetectable		 1hk3A-2w1qA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 2w1q HYALURONOGLUCOSAMINI
DASE
(Clostridium
perfringens) 		6 / 12 GLY A 869
GLY A 874
GLY A 872
THR A 937
LEU A 936
ILE A 868
 None
 0.98A 2oxtB-2w1qA:
undetectable		 2oxtB-2w1qA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 2w1q HYALURONOGLUCOSAMINI
DASE
(Clostridium
perfringens) 		6 / 12 GLY A 869
GLY A 874
GLY A 873
THR A 937
LEU A 936
ILE A 868
 None
 1.20A 2oxtB-2w1qA:
undetectable		 2oxtB-2w1qA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 2w1q HYALURONOGLUCOSAMINI
DASE
(Clostridium
perfringens) 		4 / 7 TYR A 837
VAL A 818
ASN A 822
GLY A 821
 None
 1.11A 3kmoB-2w1qA:
undetectable		 3kmoB-2w1qA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 2w1q HYALURONOGLUCOSAMINI
DASE
(Clostridium
perfringens) 		3 / 3 TYR A 886
LEU A 826
ARG A 925
 None
 0.78A 3sufB-2w1qA:
undetectable		 3sufB-2w1qA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2w1q HYALURONOGLUCOSAMINI
DASE
(Clostridium
perfringens) 		4 / 8 ILE A 851
ARG A 812
LEU A 810
GLY A 834
 None
None
None
CA  A1947 ( 4.8A)
 0.86A 3w1wA-2w1qA:
undetectable		 3w1wA-2w1qA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2w1q HYALURONOGLUCOSAMINI
DASE
(Clostridium
perfringens) 		5 / 12 GLY A 874
GLY A 872
THR A 937
LEU A 936
ILE A 868
 None
 0.94A 4n49A-2w1qA:
undetectable		 4n49A-2w1qA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2w1q HYALURONOGLUCOSAMINI
DASE
(Clostridium
perfringens) 		5 / 12 GLY A 874
GLY A 873
THR A 937
LEU A 936
ILE A 868
 None
 0.95A 4n49A-2w1qA:
undetectable		 4n49A-2w1qA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 2w1q HYALURONOGLUCOSAMINI
DASE
(Clostridium
perfringens) 		4 / 7 ASN A 890
TYR A 886
LEU A 926
PHE A 882
 None
 1.10A 4yv5A-2w1qA:
undetectable		 4yv5A-2w1qA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 2w1q HYALURONOGLUCOSAMINI
DASE
(Clostridium
perfringens) 		4 / 7 ASN A 890
TYR A 886
LEU A 926
PHE A 882
 None
 1.11A 4yv5B-2w1qA:
undetectable		 4yv5B-2w1qA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 2w1q HYALURONOGLUCOSAMINI
DASE
(Clostridium
perfringens) 		3 / 3 GLY A 874
ASP A 877
ASN A 933
 None
BTB  A1949 (-2.8A)
None
 0.60A 5jglA-2w1qA:
undetectable		 5jglA-2w1qA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 2w1q HYALURONOGLUCOSAMINI
DASE
(Clostridium
perfringens) 		5 / 12 THR A 917
GLY A 863
ILE A 924
ALA A 942
ASP A 862
 None
 1.18A 5kvaB-2w1qA:
undetectable		 5kvaB-2w1qA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 2w1q HYALURONOGLUCOSAMINI
DASE
(Clostridium
perfringens) 		4 / 6 VAL A 910
TYR A 899
ILE A 911
GLU A 913
 None
 0.92A 5z3jA-2w1qA:
undetectable		 5z3jA-2w1qA:
23.33