SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2w2j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 7 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.27A 1am6A-2w2jA:
37.1		 1am6A-2w2jA:
38.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 8 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.33A 1azmA-2w2jA:
35.0		 1azmA-2w2jA:
37.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 8 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.26A 1bzmA-2w2jA:
35.0		 1bzmA-2w2jA:
37.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 12 HIS A  87
HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 None
CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.30A 1cilA-2w2jA:
37.1		 1cilA-2w2jA:
38.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 11 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.44A 1dmyA-2w2jA:
34.4		 1dmyA-2w2jA:
32.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.37A 1dmyB-2w2jA:
34.5		 1dmyB-2w2jA:
32.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 9 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.21A 1jd0A-2w2jA:
34.7		 1jd0A-2w2jA:
32.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.20A 1jd0B-2w2jA:
34.6		 1jd0B-2w2jA:
32.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		4 / 6 ASN A  84
ASP A  85
GLY A  86
THR A  88
 None
 0.67A 1n4fA-2w2jA:
undetectable		 1n4fA-2w2jA:
18.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 12 HIS A 118
VAL A 157
LEU A 222
THR A 223
PRO A 226
TRP A 233
 CL  A 401 (-4.2A)
None
None
CL  A 401 ( 4.8A)
None
None
 0.39A 1oq5A-2w2jA:
37.5		 1oq5A-2w2jA:
38.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.29A 1rj6A-2w2jA:
35.3		 1rj6A-2w2jA:
30.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.29A 1rj6B-2w2jA:
34.9		 1rj6B-2w2jA:
30.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		4 / 6 PHE A 117
LEU A 206
PHE A 250
SER A 243
 None
 1.07A 1wrlB-2w2jA:
undetectable		 1wrlB-2w2jA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		4 / 5 PHE A 117
LEU A 206
PHE A 250
SER A 243
 None
 1.11A 1wrlC-2w2jA:
undetectable		 1wrlC-2w2jA:
14.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 HIS A 118
VAL A 157
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
None
CL  A 401 ( 4.8A)
None
 0.70A 1z9yA-2w2jA:
37.2		 1z9yA-2w2jA:
38.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.36A 1zgfA-2w2jA:
37.2		 1zgfA-2w2jA:
38.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 12 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.24A 1zsbA-2w2jA:
37.5		 1zsbA-2w2jA:
38.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 ILE A 153
HIS A 118
LEU A 222
THR A 223
TRP A 233
 UNX  A 603 ( 4.9A)
CL  A 401 (-4.2A)
None
CL  A 401 ( 4.8A)
None
 0.93A 2aw1A-2w2jA:
37.4		 2aw1A-2w2jA:
38.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		4 / 8 TYR A 218
LEU A 235
GLU A 139
ALA A 167
 None
 0.75A 2bnnA-2w2jA:
undetectable
2bnnB-2w2jA:
undetectable		 2bnnA-2w2jA:
18.37
2bnnB-2w2jA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		3 / 3 THR A 277
PRO A 279
PRO A  51
 GOL  A 502 ( 4.4A)
None
None
 0.76A 2d55C-2w2jA:
undetectable		 2d55C-2w2jA:
4.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 8 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.27A 2gehA-2w2jA:
37.4		 2gehA-2w2jA:
39.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDK_A_C2FA1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 11 THR A 241
LEU A 206
SER A 243
LEU A 140
HIS A 141
 None
None
None
None
CL  A 401 (-4.1A)
 1.49A 2idkA-2w2jA:
0.0
2idkB-2w2jA:
0.6
2idkC-2w2jA:
0.0
2idkD-2w2jA:
0.0		 2idkA-2w2jA:
20.92
2idkB-2w2jA:
20.92
2idkC-2w2jA:
20.92
2idkD-2w2jA:
20.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		4 / 8 HIS A 118
HIS A 141
LEU A 222
THR A 223
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
 0.29A 2it4A-2w2jA:
35.1		 2it4A-2w2jA:
39.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		4 / 7 PHE A 117
LEU A 253
GLU A 114
ARG A 116
 None
 0.96A 2jn3A-2w2jA:
1.2		 2jn3A-2w2jA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 222
HIS A 144
LEU A 112
LEU A 206
TYR A  74
 None
 1.42A 3adsA-2w2jA:
undetectable		 3adsA-2w2jA:
24.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.30A 3bl1A-2w2jA:
37.3		 3bl1A-2w2jA:
39.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
PRO A 226
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
None
 0.25A 3cajA-2w2jA:
37.6		 3cajA-2w2jA:
39.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
PRO A 226
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
None
 1.47A 3cajA-2w2jA:
37.6		 3cajA-2w2jA:
39.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.26A 3czvA-2w2jA:
36.9
3czvB-2w2jA:
36.8		 3czvA-2w2jA:
38.00
3czvB-2w2jA:
38.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.25A 3czvB-2w2jA:
36.8		 3czvB-2w2jA:
38.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.25A 3dazA-2w2jA:
37.4		 3dazA-2w2jA:
39.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 12 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.26A 3dc3A-2w2jA:
37.4		 3dc3A-2w2jA:
39.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.25A 3dcsA-2w2jA:
37.3		 3dcsA-2w2jA:
39.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
PRO A 226
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
None
 0.27A 3dcwA-2w2jA:
37.5		 3dcwA-2w2jA:
39.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
PRO A 226
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
None
 1.48A 3dcwA-2w2jA:
37.5		 3dcwA-2w2jA:
39.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
PRO A 226
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
None
 0.28A 3dd0A-2w2jA:
37.5		 3dd0A-2w2jA:
39.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
PRO A 226
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
None
 1.44A 3dd0A-2w2jA:
37.5		 3dd0A-2w2jA:
39.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		3 / 3 TYR A  31
ASP A  85
HIS A 141
 None
None
CL  A 401 (-4.1A)
 0.84A 3e23A-2w2jA:
undetectable		 3e23A-2w2jA:
21.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 HIS A 118
LEU A 222
THR A 223
PRO A 226
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 ( 4.8A)
None
None
 0.32A 3f4xA-2w2jA:
37.0		 3f4xA-2w2jA:
39.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 12 HIS A  87
HIS A 118
ILE A 163
LEU A 222
THR A 223
TRP A 233
 None
CL  A 401 (-4.2A)
None
None
CL  A 401 ( 4.8A)
None
 0.51A 3fw3A-2w2jA:
32.6		 3fw3A-2w2jA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 12 HIS A 118
HIS A 141
ILE A 163
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
None
CL  A 401 ( 4.8A)
None
 0.37A 3fw3B-2w2jA:
32.3		 3fw3B-2w2jA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		3 / 3 GLU A 128
HIS A 141
THR A 223
 None
CL  A 401 (-4.1A)
CL  A 401 ( 4.8A)
 0.20A 3hkuA-2w2jA:
37.4		 3hkuA-2w2jA:
39.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 11 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.29A 3hs4A-2w2jA:
37.4		 3hs4A-2w2jA:
39.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		4 / 7 VAL A 131
LYS A 134
TRP A 216
PRO A 239
 None
 0.98A 3hs4A-2w2jA:
37.4		 3hs4A-2w2jA:
39.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.26A 3iaiA-2w2jA:
34.8		 3iaiA-2w2jA:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.26A 3iaiB-2w2jA:
34.4		 3iaiB-2w2jA:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.22A 3iaiC-2w2jA:
34.3		 3iaiC-2w2jA:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.25A 3iaiD-2w2jA:
34.5		 3iaiD-2w2jA:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		7 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
PRO A 226
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
None
 0.28A 3mdzA-2w2jA:
37.2		 3mdzA-2w2jA:
40.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
HIS A 141
LEU A 222
THR A 223
PRO A 226
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
None
 1.47A 3mdzA-2w2jA:
37.2		 3mdzA-2w2jA:
40.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 11 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.22A 3ml5A-2w2jA:
37.6		 3ml5A-2w2jA:
39.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		4 / 8 LEU A  70
ASP A  62
TYR A 215
SER A  64
 None
 0.99A 3qj7A-2w2jA:
undetectable
3qj7D-2w2jA:
undetectable		 3qj7A-2w2jA:
20.58
3qj7D-2w2jA:
20.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 11 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.29A 3v2jA-2w2jA:
37.4		 3v2jA-2w2jA:
39.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.27A 3v2mA-2w2jA:
37.4		 3v2mA-2w2jA:
39.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 8 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.27A 3w6hA-2w2jA:
35.1		 3w6hA-2w2jA:
37.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 9 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.28A 3w6hB-2w2jA:
35.1		 3w6hB-2w2jA:
37.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.34A 3zncA-2w2jA:
32.1		 3zncA-2w2jA:
28.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.25A 4coqA-2w2jA:
29.7		 4coqA-2w2jA:
33.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 9 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.27A 4coqB-2w2jA:
29.7		 4coqB-2w2jA:
33.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.26A 4g0cA-2w2jA:
37.3		 4g0cA-2w2jA:
38.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.23A 4g7aA-2w2jA:
29.4		 4g7aA-2w2jA:
30.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.25A 4g7aB-2w2jA:
29.3		 4g7aB-2w2jA:
30.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 11 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.32A 4k0sA-2w2jA:
37.6		 4k0sA-2w2jA:
38.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 12 HIS A 118
HIS A 141
LEU A 222
THR A 223
PRO A 226
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
None
 0.21A 4k0zA-2w2jA:
37.3		 4k0zA-2w2jA:
38.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 12 HIS A 118
HIS A 141
LEU A 222
THR A 223
PRO A 226
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
None
 1.44A 4k0zA-2w2jA:
37.3		 4k0zA-2w2jA:
38.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.25A 4k13A-2w2jA:
37.5		 4k13A-2w2jA:
38.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 11 GLY A 107
LEU A 104
GLY A 101
ILE A  52
LEU A 280
 None
 1.12A 4kt0A-2w2jA:
undetectable
4kt0J-2w2jA:
undetectable		 4kt0A-2w2jA:
18.03
4kt0J-2w2jA:
9.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.31A 4lu3A-2w2jA:
34.6		 4lu3A-2w2jA:
31.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 HIS A 118
LEU A 222
THR A 223
PRO A 226
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 ( 4.8A)
None
None
 0.30A 4m2rA-2w2jA:
37.5		 4m2rA-2w2jA:
38.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 12 TRP A  29
HIS A  87
HIS A 118
LEU A 222
THR A 223
TRP A 233
 None
None
CL  A 401 (-4.2A)
None
CL  A 401 ( 4.8A)
None
 0.38A 4m2uA-2w2jA:
37.4		 4m2uA-2w2jA:
38.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 HIS A 118
VAL A 157
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
None
CL  A 401 ( 4.8A)
None
 0.43A 4m2vA-2w2jA:
37.4		 4m2vA-2w2jA:
38.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.25A 4m2wA-2w2jA:
37.5		 4m2wA-2w2jA:
38.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		4 / 8 ILE A 153
HIS A 118
HIS A 141
THR A 223
 UNX  A 603 ( 4.9A)
CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
CL  A 401 ( 4.8A)
 0.84A 4n16A-2w2jA:
37.5		 4n16A-2w2jA:
39.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.25A 4uovA-2w2jA:
29.5		 4uovA-2w2jA:
33.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.21A 4uovB-2w2jA:
29.7		 4uovB-2w2jA:
33.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.24A 4uovC-2w2jA:
29.4		 4uovC-2w2jA:
33.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.25A 4uovD-2w2jA:
29.5		 4uovD-2w2jA:
33.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.23A 4uovE-2w2jA:
29.6		 4uovE-2w2jA:
33.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.23A 4uovF-2w2jA:
29.7		 4uovF-2w2jA:
33.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.27A 4x5sA-2w2jA:
28.7		 4x5sA-2w2jA:
32.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.27A 4x5sB-2w2jA:
28.7		 4x5sB-2w2jA:
32.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 12 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.28A 4xiwA-2w2jA:
25.5
4xiwH-2w2jA:
25.5		 4xiwA-2w2jA:
30.90
4xiwH-2w2jA:
30.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 12 GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
VAL A 157
 None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
None
 1.18A 4xiwB-2w2jA:
25.3
4xiwE-2w2jA:
25.7		 4xiwB-2w2jA:
30.90
4xiwE-2w2jA:
30.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 12 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.31A 4xiwB-2w2jA:
25.3
4xiwE-2w2jA:
25.7		 4xiwB-2w2jA:
30.90
4xiwE-2w2jA:
30.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.31A 4xiwC-2w2jA:
25.5		 4xiwC-2w2jA:
30.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.23A 4xiwD-2w2jA:
25.6		 4xiwD-2w2jA:
30.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.24A 4xiwE-2w2jA:
25.7		 4xiwE-2w2jA:
30.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.26A 4xiwF-2w2jA:
25.5		 4xiwF-2w2jA:
30.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 12 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.45A 4xiwG-2w2jA:
25.4		 4xiwG-2w2jA:
30.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.28A 4xiwH-2w2jA:
25.5		 4xiwH-2w2jA:
30.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 11 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.30A 4ygfA-2w2jA:
26.1		 4ygfA-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.42A 4ygfB-2w2jA:
25.8		 4ygfB-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 11 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.24A 4ygfC-2w2jA:
20.0		 4ygfC-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.32A 4ygfD-2w2jA:
25.3		 4ygfD-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 12 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.36A 4ygfE-2w2jA:
26.1		 4ygfE-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 9 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.27A 4ygfF-2w2jA:
25.9		 4ygfF-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.27A 4ygfG-2w2jA:
26.0		 4ygfG-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 9 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.23A 4ygfH-2w2jA:
25.7		 4ygfH-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.36A 4yhaA-2w2jA:
26.0		 4yhaA-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 11 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.36A 4yhaC-2w2jA:
26.2		 4yhaC-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.42A 4yhaD-2w2jA:
25.0		 4yhaD-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 12 HIS A 118
HIS A 141
LEU A 222
THR A 223
PRO A 226
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
None
 0.29A 4yhaE-2w2jA:
26.1		 4yhaE-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 12 HIS A 118
HIS A 141
LEU A 222
THR A 223
PRO A 226
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
None
 1.47A 4yhaE-2w2jA:
26.1		 4yhaE-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_F_MZMF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.59A 4yhaF-2w2jA:
23.4		 4yhaF-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.39A 4yhaG-2w2jA:
25.6		 4yhaG-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_H_MZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 10 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.37A 4yhaH-2w2jA:
25.7		 4yhaH-2w2jA:
27.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 12 HIS A 118
GLU A 128
LEU A 222
THR A 223
PRO A 226
TRP A 233
 CL  A 401 (-4.2A)
None
None
CL  A 401 ( 4.8A)
None
None
 0.25A 5c8iA-2w2jA:
37.4		 5c8iA-2w2jA:
39.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.24A 5jn8A-2w2jA:
32.2		 5jn8A-2w2jA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.22A 5jn8B-2w2jA:
32.3		 5jn8B-2w2jA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 9 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.25A 5jn8C-2w2jA:
32.2		 5jn8C-2w2jA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 10 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.20A 5jn8D-2w2jA:
31.8		 5jn8D-2w2jA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.21A 5jn9A-2w2jA:
32.3		 5jn9A-2w2jA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.19A 5jn9B-2w2jA:
32.3		 5jn9B-2w2jA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 9 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.21A 5jn9C-2w2jA:
32.2		 5jn9C-2w2jA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.20A 5jn9D-2w2jA:
31.8		 5jn9D-2w2jA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
 0.24A 5jnaA-2w2jA:
32.2		 5jnaA-2w2jA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.26A 5jnaB-2w2jA:
32.3		 5jnaB-2w2jA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.26A 5jnaD-2w2jA:
31.8		 5jnaD-2w2jA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 11 HIS A 118
GLU A 128
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
None
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.23A 5jncA-2w2jA:
32.2		 5jncA-2w2jA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.21A 5jncB-2w2jA:
32.3		 5jncB-2w2jA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 9 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.22A 5jncC-2w2jA:
32.1		 5jncC-2w2jA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 9 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.22A 5jncD-2w2jA:
31.8		 5jncD-2w2jA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.19A 5ku6A-2w2jA:
32.2		 5ku6A-2w2jA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.19A 5ku6B-2w2jA:
32.3		 5ku6B-2w2jA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 9 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.21A 5ku6C-2w2jA:
32.2		 5ku6C-2w2jA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 9 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.19A 5ku6D-2w2jA:
31.9		 5ku6D-2w2jA:
31.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		4 / 7 VAL A  91
PHE A 117
LEU A 206
THR A 205
 None
 0.93A 5m78A-2w2jA:
37.4		 5m78A-2w2jA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
PRO A 226
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
None
 0.29A 5tt3A-2w2jA:
25.9		 5tt3A-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 9 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.42A 5tt3B-2w2jA:
25.0		 5tt3B-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 10 HIS A 118
HIS A 141
LEU A 222
THR A 223
PRO A 226
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
None
 0.34A 5tt3C-2w2jA:
26.1		 5tt3C-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 9 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.29A 5tt3E-2w2jA:
26.1		 5tt3E-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 8 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.43A 5tt3F-2w2jA:
25.2		 5tt3F-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 9 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.32A 5tt3G-2w2jA:
25.1		 5tt3G-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 8 HIS A 118
HIS A 141
LEU A 222
THR A 223
TRP A 233
 CL  A 401 (-4.2A)
CL  A 401 (-4.1A)
None
CL  A 401 ( 4.8A)
None
 0.39A 5tt3H-2w2jA:
25.4		 5tt3H-2w2jA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 HIS A  87
ILE A 153
HIS A 118
THR A 223
TRP A 233
 None
UNX  A 603 ( 4.9A)
CL  A 401 (-4.2A)
CL  A 401 ( 4.8A)
None
 0.81A 6bbsA-2w2jA:
30.1		 6bbsA-2w2jA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 12 TRP A  29
HIS A  87
HIS A 118
LEU A 222
THR A 223
TRP A 233
 None
None
CL  A 401 (-4.2A)
None
CL  A 401 ( 4.8A)
None
 0.57A 6bbsA-2w2jA:
30.1		 6bbsA-2w2jA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 12 TRP A  29
HIS A 118
LEU A 222
THR A 223
PRO A 226
TRP A 233
 None
CL  A 401 (-4.2A)
None
CL  A 401 ( 4.8A)
None
None
 0.38A 6bc9A-2w2jA:
37.3		 6bc9A-2w2jA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 2w2j CARBONIC
ANHYDRASE-RELATED
PROTEIN
(Homo
sapiens) 		6 / 12 HIS A 118
VAL A 157
LEU A 222
THR A 223
PRO A 226
TRP A 233
 CL  A 401 (-4.2A)
None
None
CL  A 401 ( 4.8A)
None
None
 0.37A 6bccA-2w2jA:
37.4		 6bccA-2w2jA:
22.40