SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2w2r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 2w2r MATRIX PROTEIN
(Vesicular
stomatitis
virus) 		5 / 12 LEU A 171
ASN A  93
ALA A  87
ALA A 109
GLY A 209
 None
 1.06A 3c6gA-2w2rA:
undetectable		 3c6gA-2w2rA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_C_ACHC301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2w2r MATRIX PROTEIN
(Vesicular
stomatitis
virus) 		4 / 8 TYR A 105
TYR A  95
TRP A  91
ARG A 159
 None
 1.33A 3wipC-2w2rA:
undetectable
3wipD-2w2rA:
undetectable		 3wipC-2w2rA:
21.97
3wipD-2w2rA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 2w2r MATRIX PROTEIN
(Vesicular
stomatitis
virus) 		3 / 3 TYR A 132
THR A 119
THR A  71
 None
 0.81A 5aoxB-2w2rA:
undetectable		 5aoxB-2w2rA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 2w2r MATRIX PROTEIN
(Vesicular
stomatitis
virus) 		3 / 3 TYR A 132
THR A 119
THR A  71
 None
 0.82A 5aoxE-2w2rA:
undetectable		 5aoxE-2w2rA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 2w2r MATRIX PROTEIN
(Vesicular
stomatitis
virus) 		5 / 12 VAL A  88
ALA A 109
SER A 113
GLY A 209
LEU A 210
 None
 1.27A 5m54E-2w2rA:
undetectable		 5m54E-2w2rA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_0
(REGULATORY PROTEIN
TETR)		 2w2r MATRIX PROTEIN
(Vesicular
stomatitis
virus) 		5 / 12 ALA A 133
VAL A  72
TYR A 167
ASP A  83
THR A  85
 None
 1.45A 5vlmD-2w2rA:
undetectable		 5vlmD-2w2rA:
19.25