SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2w31'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 2w31 GLOBIN
(Geobacter
sulfurreducens) 		3 / 3 ALA A  92
HIS A  93
VAL A  96
 HEM  A 200 ( 3.8A)
HEM  A 200 (-3.5A)
HEM  A 200 (-4.6A)
 0.48A 1lqtB-2w31A:
undetectable		 1lqtB-2w31A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 2w31 GLOBIN
(Geobacter
sulfurreducens) 		3 / 3 ALA A  92
HIS A  93
VAL A  96
 HEM  A 200 ( 3.8A)
HEM  A 200 (-3.5A)
HEM  A 200 (-4.6A)
 0.49A 1lquB-2w31A:
undetectable		 1lquB-2w31A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_B_SAMB301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 2w31 GLOBIN
(Geobacter
sulfurreducens) 		5 / 12 PHE A  25
ILE A 138
GLY A  22
GLU A 136
ALA A  28
 None
 1.02A 1vq1B-2w31A:
undetectable		 1vq1B-2w31A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 2w31 GLOBIN
(Geobacter
sulfurreducens) 		5 / 10 TYR A  78
ALA A 134
THR A 114
MET A 107
VAL A 110
 None
None
None
HEM  A 200 (-3.9A)
None
 1.28A 2wuzA-2w31A:
undetectable		 2wuzA-2w31A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 2w31 GLOBIN
(Geobacter
sulfurreducens) 		3 / 3 ASN A  31
MET A 107
PHE A  70
 None
HEM  A 200 (-3.9A)
None
 1.11A 3g4lD-2w31A:
undetectable		 3g4lD-2w31A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2w31 GLOBIN
(Geobacter
sulfurreducens) 		3 / 3 GLN A  67
GLU A  29
LYS A  32
 None
GOL  A 201 (-2.9A)
GOL  A 201 ( 4.2A)
 1.16A 3su9A-2w31A:
undetectable		 3su9A-2w31A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 2w31 GLOBIN
(Geobacter
sulfurreducens) 		3 / 3 MET A 146
MET A   1
TYR A  82
 HEM  A 200 ( 3.7A)
None
None
 1.38A 4p6xI-2w31A:
2.5		 4p6xI-2w31A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 2w31 GLOBIN
(Geobacter
sulfurreducens) 		5 / 12 TYR A  82
LEU A  86
ILE A 138
THR A 114
VAL A 110
 None
 1.02A 6djzA-2w31A:
undetectable		 6djzA-2w31A:
22.27