SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2w55'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 10 GLY B 456
HIS B 314
ALA B 529
ILE B 457
GLY B 345
 None
None
HPA  B1780 ( 3.2A)
None
None
 0.91A 1c9sN-2w55B:
undetectable
1c9sO-2w55B:
undetectable		 1c9sN-2w55B:
7.21
1c9sO-2w55B:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 11 GLY B 456
HIS B 314
ALA B 529
ILE B 457
GLY B 345
 None
None
HPA  B1780 ( 3.2A)
None
None
 0.91A 1c9sP-2w55B:
undetectable
1c9sQ-2w55B:
undetectable		 1c9sP-2w55B:
7.21
1c9sQ-2w55B:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 10 GLY B 345
GLY B 456
HIS B 314
ALA B 529
ILE B 457
 None
None
None
HPA  B1780 ( 3.2A)
None
 0.90A 1c9sL-2w55B:
undetectable
1c9sV-2w55B:
undetectable		 1c9sL-2w55B:
7.21
1c9sV-2w55B:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 7 ILE B 278
TYR B 276
PHE B 291
PHE B 166
 None
 1.15A 1e71M-2w55B:
undetectable		 1e71M-2w55B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 7 ILE B 278
TYR B 276
PHE B 291
PHE B 166
 None
 1.15A 1e72M-2w55B:
undetectable		 1e72M-2w55B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 6 ILE B 278
TYR B 276
PHE B 291
PHE B 166
 None
 1.15A 1e73M-2w55B:
undetectable		 1e73M-2w55B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 9 ILE B 118
LEU B  86
GLY B  38
ALA B 116
LEU B  52
 None
 1.17A 1e7bA-2w55B:
undetectable		 1e7bA-2w55B:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 7 GLN B 234
THR B 339
SER B 337
GLN B 197
 None
None
None
XAX  B1778 (-3.5A)
 1.32A 1eiiA-2w55B:
undetectable		 1eiiA-2w55B:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_CUC1_0
(BETA-CARBONIC
ANHYDRASE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 6 CYH B 297
CYH B 308
SER B 304
ARG B 330
 None
 1.36A 1ekjC-2w55B:
0.5
1ekjD-2w55B:
0.0		 1ekjC-2w55B:
14.87
1ekjD-2w55B:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_CUE3_0
(BETA-CARBONIC
ANHYDRASE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 6 CYH B 297
CYH B 308
SER B 304
ARG B 330
 None
 1.38A 1ekjE-2w55B:
0.0
1ekjF-2w55B:
0.0		 1ekjE-2w55B:
14.87
1ekjF-2w55B:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_CUE3_0
(BETA-CARBONIC
ANHYDRASE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 6 CYH B 308
SER B 304
ARG B 330
CYH B 297
 None
 1.35A 1ekjE-2w55B:
0.0
1ekjF-2w55B:
0.0		 1ekjE-2w55B:
14.87
1ekjF-2w55B:
14.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 8 LEU B 303
ARG B 310
PHE B 344
LEU B 461
 None
HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
None
 0.87A 1fiqC-2w55B:
53.6		 1fiqC-2w55B:
40.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		6 / 8 LEU B 303
ARG B 310
PHE B 344
THR B 460
LEU B 464
ALA B 529
 None
HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
None
HPA  B1780 ( 3.2A)
 0.35A 1fiqC-2w55B:
53.6		 1fiqC-2w55B:
40.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_A_SALA3005_1
(XANTHINE
DEHYDROGENASE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		6 / 9 LEU B 303
ARG B 310
PHE B 344
THR B 460
LEU B 464
ALA B 529
 None
HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
None
HPA  B1780 ( 3.2A)
 0.41A 1fo4A-2w55B:
43.4		 1fo4A-2w55B:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 7 ARG B 310
PHE B 344
THR B 460
ALA B 528
 HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
XAX  B1778 ( 3.2A)
 0.33A 1fo4B-2w55B:
35.1		 1fo4B-2w55B:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 11 GLY B 456
HIS B 314
ALA B 529
ILE B 457
GLY B 345
 None
None
HPA  B1780 ( 3.2A)
None
None
 0.91A 1gtfQ-2w55B:
undetectable
1gtfR-2w55B:
undetectable		 1gtfQ-2w55B:
7.21
1gtfR-2w55B:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 11 GLY B 456
HIS B 314
ALA B 529
ILE B 457
GLY B 345
 None
None
HPA  B1780 ( 3.2A)
None
None
 0.91A 1gtfS-2w55B:
undetectable
1gtfT-2w55B:
undetectable		 1gtfS-2w55B:
7.21
1gtfT-2w55B:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 11 GLY B 456
HIS B 314
ALA B 529
ILE B 457
GLY B 345
 None
None
HPA  B1780 ( 3.2A)
None
None
 0.92A 1gtnT-2w55B:
undetectable
1gtnU-2w55B:
undetectable		 1gtnT-2w55B:
7.21
1gtnU-2w55B:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 GLY B 345
GLY B 456
HIS B 314
ALA B 529
ILE B 457
 None
None
None
HPA  B1780 ( 3.2A)
None
 0.92A 1gtnL-2w55B:
undetectable
1gtnV-2w55B:
undetectable		 1gtnL-2w55B:
7.21
1gtnV-2w55B:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 11 GLY B 489
GLY B 491
GLU B 487
ARG B 223
GLY B 225
 XAX  B1778 (-3.4A)
None
None
None
None
 1.03A 1jg3A-2w55B:
undetectable		 1jg3A-2w55B:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 11 GLY B 489
GLY B 491
GLU B 487
ARG B 223
GLY B 225
 XAX  B1778 (-3.4A)
None
None
None
None
 1.01A 1jg3B-2w55B:
undetectable		 1jg3B-2w55B:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		6 / 12 LEU B 303
ARG B 310
PHE B 344
THR B 460
ALA B 528
ALA B 529
 None
HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
XAX  B1778 ( 3.2A)
HPA  B1780 ( 3.2A)
 0.34A 1n5xA-2w55B:
55.7		 1n5xA-2w55B:
26.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		6 / 12 LEU B 303
ARG B 310
PHE B 344
THR B 460
ALA B 528
ALA B 529
 None
HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
XAX  B1778 ( 3.2A)
HPA  B1780 ( 3.2A)
 0.34A 1n5xB-2w55B:
55.8		 1n5xB-2w55B:
26.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 7 PHE B 733
ARG B 269
ILE B 698
GLU B 678
 None
 1.08A 1oniA-2w55B:
undetectable
1oniB-2w55B:
undetectable		 1oniA-2w55B:
11.34
1oniB-2w55B:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_G_BEZG513_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 5 PHE B 733
ARG B 269
ILE B 698
GLU B 678
 None
 1.10A 1oniG-2w55B:
1.1
1oniH-2w55B:
undetectable		 1oniG-2w55B:
11.34
1oniH-2w55B:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 4 ALA B 109
VAL B  61
ALA B 103
HIS B  34
 None
 1.25A 1q23K-2w55B:
undetectable		 1q23K-2w55B:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 GLY B 456
HIS B 314
ALA B 529
ILE B 457
GLY B 345
 None
None
HPA  B1780 ( 3.2A)
None
None
 0.91A 1utdO-2w55B:
undetectable
1utdP-2w55B:
undetectable		 1utdO-2w55B:
7.21
1utdP-2w55B:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 11 GLY B 456
HIS B 314
ALA B 529
ILE B 457
GLY B 345
 None
None
HPA  B1780 ( 3.2A)
None
None
 0.92A 1utdP-2w55B:
undetectable
1utdQ-2w55B:
undetectable		 1utdP-2w55B:
7.21
1utdQ-2w55B:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 11 GLY B 456
HIS B 314
ALA B 529
ILE B 457
GLY B 345
 None
None
HPA  B1780 ( 3.2A)
None
None
 0.90A 1utdS-2w55B:
undetectable
1utdT-2w55B:
undetectable		 1utdS-2w55B:
7.21
1utdT-2w55B:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 10 GLY B 456
HIS B 314
ALA B 529
ILE B 457
GLY B 345
 None
None
HPA  B1780 ( 3.2A)
None
None
 0.91A 1utdU-2w55B:
undetectable
1utdV-2w55B:
undetectable		 1utdU-2w55B:
7.21
1utdV-2w55B:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WYG_A_SALA4005_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		8 / 10 LEU B 303
ARG B 310
PHE B 344
PHE B 459
THR B 460
ALA B 528
ALA B 529
GLU B 730
 None
HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-4.8A)
HPA  B1780 (-3.6A)
XAX  B1778 ( 3.2A)
HPA  B1780 ( 3.2A)
XAX  B1778 (-3.3A)
 0.51A 1wygA-2w55B:
48.4		 1wygA-2w55B:
26.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WYG_A_SALA4005_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 10 LEU B 303
PHE B 344
PHE B 459
ALA B 528
GLU B 730
 None
HPA  B1780 (-3.4A)
HPA  B1780 (-4.8A)
XAX  B1778 ( 3.2A)
XAX  B1778 (-3.3A)
 1.48A 1wygA-2w55B:
48.4		 1wygA-2w55B:
26.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A69_M_RPTM8002_1
(DNA-DIRECTED RNA
POLYMERASE BETA
CHAIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 GLN B 472
ASP B  10
ARG B 223
HIS B 493
ARG B 222
 None
 1.34A 2a69M-2w55B:
0.0		 2a69M-2w55B:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 6 ARG B 310
PHE B 344
THR B 460
LEU B 464
ALA B 529
 HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
None
HPA  B1780 ( 3.2A)
 0.43A 2e1qA-2w55B:
43.5		 2e1qA-2w55B:
26.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_B_SALB3006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 4 ARG B 310
PHE B 344
THR B 460
ALA B 529
 HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
HPA  B1780 ( 3.2A)
 0.36A 2e1qB-2w55B:
47.4		 2e1qB-2w55B:
26.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 6 ARG B 310
PHE B 344
THR B 460
LEU B 464
ALA B 529
 HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
None
HPA  B1780 ( 3.2A)
 0.41A 2e1qC-2w55B:
56.8		 2e1qC-2w55B:
26.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 5 ARG B 310
PHE B 344
THR B 460
LEU B 464
ALA B 529
 HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
None
HPA  B1780 ( 3.2A)
 0.38A 2e1qD-2w55B:
52.5		 2e1qD-2w55B:
26.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 7 VAL B 206
ALA B 239
PHE B 214
THR B 518
 None
 0.89A 2q6oA-2w55B:
undetectable		 2q6oA-2w55B:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 8 THR B  41
VAL B 264
ASP B 261
ILE B 265
 None
 0.93A 2qbmA-2w55B:
undetectable		 2qbmA-2w55B:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 8 LEU B 464
LEU B 461
ALA B 529
ALA B 340
 None
None
HPA  B1780 ( 3.2A)
XAX  B1778 ( 4.1A)
 0.80A 2vcvP-2w55B:
undetectable		 2vcvP-2w55B:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 5 ARG B 362
ASP B 745
ILE B 448
GLU B 358
 None
 1.33A 2xrzA-2w55B:
undetectable
2xrzB-2w55B:
undetectable		 2xrzA-2w55B:
19.76
2xrzB-2w55B:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 8 GLN B 348
PHE B 344
GLY B 345
GLY B 230
 None
HPA  B1780 (-3.4A)
None
None
 0.91A 2y6rB-2w55B:
undetectable		 2y6rB-2w55B:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 5 GLN B 232
THR B 516
HIS B 483
LEU B 492
 HPA  B1780 ( 3.1A)
None
None
XAX  B1778 (-3.9A)
 1.24A 2zj0A-2w55B:
undetectable		 2zj0A-2w55B:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		3 / 3 PRO B  27
LEU B  26
ARG B 223
 None
 0.89A 3aqiA-2w55B:
undetectable		 3aqiA-2w55B:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 8 ARG B 310
PHE B 344
THR B 460
LEU B 464
ALA B 529
 HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
None
HPA  B1780 ( 3.2A)
 0.43A 3ax7A-2w55B:
49.9		 3ax7A-2w55B:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_B_SALB1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		6 / 9 ARG B 310
PHE B 344
THR B 460
LEU B 464
ALA B 528
ALA B 529
 HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
None
XAX  B1778 ( 3.2A)
HPA  B1780 ( 3.2A)
 0.41A 3ax7B-2w55B:
51.4		 3ax7B-2w55B:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 8 LEU B 303
ARG B 310
PHE B 344
THR B 460
ALA B 529
 None
HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
HPA  B1780 ( 3.2A)
 0.40A 3ax9A-2w55B:
52.8		 3ax9A-2w55B:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		6 / 8 LEU B 303
ARG B 310
PHE B 344
THR B 460
ALA B 528
ALA B 529
 None
HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
XAX  B1778 ( 3.2A)
HPA  B1780 ( 3.2A)
 0.29A 3ax9B-2w55B:
56.5		 3ax9B-2w55B:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		3 / 3 SER B 195
GLY B 225
GLY B 227
 None
None
XAX  B1778 (-3.3A)
 0.53A 3bogA-2w55B:
undetectable
3bogC-2w55B:
undetectable		 3bogA-2w55B:
undetectable
3bogC-2w55B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_B_SALB258_1
(TRANSCRIPTIONAL
REGULATOR)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 11 ALA B 449
ARG B 431
ILE B 434
GLY B 447
ARG B 362
 None
 1.05A 3bpxA-2w55B:
undetectable
3bpxB-2w55B:
undetectable		 3bpxA-2w55B:
10.17
3bpxB-2w55B:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 5 GLN B 232
THR B 516
HIS B 483
LEU B 492
 HPA  B1780 ( 3.1A)
None
None
XAX  B1778 (-3.9A)
 1.24A 3ce6A-2w55B:
undetectable		 3ce6A-2w55B:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 5 GLN B 232
THR B 516
HIS B 483
LEU B 492
 HPA  B1780 ( 3.1A)
None
None
XAX  B1778 (-3.9A)
 1.24A 3ce6C-2w55B:
undetectable		 3ce6C-2w55B:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_1
(CYTOCHROME P450 2R1)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 THR B 527
VAL B 540
ALA B 469
VAL B 511
ILE B 513
 XAX  B1778 ( 4.9A)
None
None
None
None
 0.98A 3czhA-2w55B:
undetectable		 3czhA-2w55B:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_0
(CYTOCHROME P450 2R1)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 THR B 527
VAL B 540
ALA B 469
VAL B 511
ILE B 513
 XAX  B1778 ( 4.9A)
None
None
None
None
 0.99A 3dl9A-2w55B:
undetectable		 3dl9A-2w55B:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 8 ARG B 310
THR B 460
LEU B 461
ALA B 529
 HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
None
HPA  B1780 ( 3.2A)
 0.71A 3hrdA-2w55B:
26.1
3hrdB-2w55B:
20.7		 3hrdA-2w55B:
19.60
3hrdB-2w55B:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 ILE B 722
GLY B 537
ALA B 469
ALA B 500
VAL B 499
 None
 0.88A 3jb2A-2w55B:
undetectable		 3jb2A-2w55B:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 ILE B 722
GLY B 537
ALA B 469
ALA B 500
VAL B 499
 None
 0.81A 3jb3A-2w55B:
undetectable		 3jb3A-2w55B:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 GLY B 349
ASP B 316
VAL B 409
GLY B 456
PHE B 733
 None
 1.15A 3k13C-2w55B:
undetectable		 3k13C-2w55B:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 7 GLU B 433
TRP B 437
LEU B 444
ASN B 441
 None
 1.32A 3k8mA-2w55B:
undetectable		 3k8mA-2w55B:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 GLN B 197
GLY B 225
GLY B 227
LEU B 176
GLU B 487
 XAX  B1778 (-3.5A)
None
XAX  B1778 (-3.3A)
None
None
 1.07A 3kkzA-2w55B:
undetectable		 3kkzA-2w55B:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 7 GLN B 510
ARG B 581
ILE B 506
PHE B 582
 None
 0.99A 3ln1C-2w55B:
undetectable		 3ln1C-2w55B:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEE_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 PRO B 452
LEU B 414
VAL B 409
TYR B 319
PHE B 622
 None
 1.40A 3meeA-2w55B:
undetectable		 3meeA-2w55B:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEG_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 PRO B 452
LEU B 414
VAL B 409
TYR B 319
PHE B 622
 None
 1.39A 3megA-2w55B:
undetectable		 3megA-2w55B:
19.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NS1_C_PM6C1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 6 ARG B 310
PHE B 344
THR B 460
ALA B 528
ALA B 529
 HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
XAX  B1778 ( 3.2A)
HPA  B1780 ( 3.2A)
 0.44A 3ns1C-2w55B:
55.5		 3ns1C-2w55B:
40.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		6 / 8 ARG B 310
PHE B 344
THR B 460
LEU B 464
ALA B 528
ALA B 529
 HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
None
XAX  B1778 ( 3.2A)
HPA  B1780 ( 3.2A)
 0.42A 3ns1L-2w55B:
48.9		 3ns1L-2w55B:
40.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		3 / 3 ILE B 585
VAL B 555
ARG B 558
 None
 0.57A 3p73A-2w55B:
undetectable		 3p73A-2w55B:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 MET B 255
LEU B  35
LEU B  33
ALA B 103
GLY B  38
 None
 1.00A 3q95B-2w55B:
undetectable		 3q95B-2w55B:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 5 HIS B 483
ILE B 513
HIS B 493
LEU B 492
 None
None
None
XAX  B1778 (-3.9A)
 1.23A 3qpkA-2w55B:
undetectable		 3qpkA-2w55B:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 GLY B 415
VAL B 453
ARG B 362
ALA B 373
ARG B 372
 None
 1.07A 3sugA-2w55B:
undetectable		 3sugA-2w55B:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		3 / 3 SER B 530
ASP B 660
ASP B 714
 XAX  B1778 (-4.9A)
None
None
 0.90A 3uj7A-2w55B:
undetectable		 3uj7A-2w55B:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_A_SALA1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		6 / 9 LEU B 303
ARG B 310
PHE B 344
THR B 460
LEU B 464
ALA B 529
 None
HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
None
HPA  B1780 ( 3.2A)
 0.40A 3unaA-2w55B:
58.4		 3unaA-2w55B:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		6 / 9 LEU B 303
ARG B 310
PHE B 344
THR B 460
LEU B 464
ALA B 529
 None
HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
None
HPA  B1780 ( 3.2A)
 0.39A 3unaB-2w55B:
51.7		 3unaB-2w55B:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		6 / 9 LEU B 303
ARG B 310
PHE B 344
THR B 460
LEU B 464
ALA B 529
 None
HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
None
HPA  B1780 ( 3.2A)
 0.42A 3uncA-2w55B:
55.9		 3uncA-2w55B:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		6 / 9 LEU B 303
ARG B 310
PHE B 344
THR B 460
LEU B 464
ALA B 529
 None
HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
None
HPA  B1780 ( 3.2A)
 0.41A 3uncB-2w55B:
47.0		 3uncB-2w55B:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 7 ARG B 310
PHE B 344
THR B 460
LEU B 464
ALA B 529
 HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
None
HPA  B1780 ( 3.2A)
 0.39A 3uniA-2w55B:
51.7		 3uniA-2w55B:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		6 / 8 LEU B 303
ARG B 310
PHE B 344
THR B 460
LEU B 464
ALA B 529
 None
HPA  B1780 (-3.4A)
HPA  B1780 (-3.4A)
HPA  B1780 (-3.6A)
None
HPA  B1780 ( 3.2A)
 0.41A 3uniB-2w55B:
56.6		 3uniB-2w55B:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 6 HIS B 237
GLU B  83
ASP B  75
PRO B  78
 None
 1.39A 4apjA-2w55B:
undetectable
4apjP-2w55B:
undetectable		 4apjA-2w55B:
21.85
4apjP-2w55B:
1.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_F_ACTF701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 4 PHE B 291
HIS B 293
GLY B 352
ILE B 274
 None
 1.09A 4k50E-2w55B:
0.0		 4k50E-2w55B:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_M_ACTM503_0
(RNA POLYMERASE
3D-POL)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 4 PHE B 291
HIS B 293
GLY B 352
ILE B 274
 None
 1.05A 4k50M-2w55B:
0.1		 4k50M-2w55B:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 6 GLY B 671
PRO B 347
HIS B 314
ARG B 269
 None
 1.11A 4lajA-2w55B:
undetectable
4lajB-2w55B:
undetectable		 4lajA-2w55B:
18.22
4lajB-2w55B:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 ILE B 473
VAL B 479
VAL B 497
ALA B 500
LEU B 547
 None
 1.14A 4m11C-2w55B:
undetectable		 4m11C-2w55B:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_1
(DIHYDROFOLATE
REDUCTASE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 ASP B 756
PHE B 166
LEU B 675
LEU B 351
ILE B 168
 None
 1.00A 4m2xA-2w55B:
undetectable		 4m2xA-2w55B:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 MET B 255
LEU B  35
LEU B  33
ALA B 103
GLY B  38
 None
 1.01A 4pxmA-2w55B:
undetectable		 4pxmA-2w55B:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UAC_A_ACRA501_2
(CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-))		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 7 PRO B   8
SER B  11
GLU B 487
ASP B  25
 None
 1.19A 4uacA-2w55B:
undetectable		 4uacA-2w55B:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 6 TYR B 319
PRO B 452
TYR B 624
LEU B 414
 None
 1.16A 5bmvB-2w55B:
undetectable		 5bmvB-2w55B:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 8 ILE B 722
PHE B 723
GLN B 498
SER B   2
 None
 1.16A 5dqyA-2w55B:
undetectable		 5dqyA-2w55B:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 7 ILE B  62
HIS B  34
LEU B  35
ALA B 109
 None
 0.89A 5hrqE-2w55B:
undetectable
5hrqF-2w55B:
undetectable
5hrqJ-2w55B:
undetectable		 5hrqE-2w55B:
2.58
5hrqF-2w55B:
4.45
5hrqJ-2w55B:
4.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		3 / 3 ARG B 581
ILE B 506
PHE B 582
 None
 0.72A 5kirA-2w55B:
undetectable		 5kirA-2w55B:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		3 / 3 GLU B 172
HIS B 173
ARG B 269
 BA  B1779 (-3.2A)
BA  B1779 (-4.3A)
None
 0.92A 5uunA-2w55B:
undetectable		 5uunA-2w55B:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		4 / 8 PRO B 306
THR B 460
TRP B 674
ALA B 528
 HPA  B1780 (-4.8A)
HPA  B1780 (-3.6A)
None
XAX  B1778 ( 3.2A)
 1.01A 5x2tI-2w55B:
undetectable
5x2tJ-2w55B:
undetectable
5x2tK-2w55B:
undetectable
5x2tL-2w55B:
undetectable		 5x2tI-2w55B:
11.04
5x2tJ-2w55B:
10.86
5x2tK-2w55B:
11.04
5x2tL-2w55B:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 PHE B 272
ARG B 330
TRP B 146
HIS B 404
THR B 460
 None
None
None
None
HPA  B1780 (-3.6A)
 1.36A 5xioA-2w55B:
undetectable		 5xioA-2w55B:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_B_HFGB802_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 PHE B 272
ARG B 330
TRP B 146
HIS B 404
THR B 460
 None
None
None
None
HPA  B1780 (-3.6A)
 1.35A 5xioB-2w55B:
undetectable		 5xioB-2w55B:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_B_HFGB1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 PHE B 272
ARG B 330
TRP B 146
HIS B 404
THR B 460
 None
None
None
None
HPA  B1780 (-3.6A)
 1.39A 5xipB-2w55B:
undetectable		 5xipB-2w55B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 PHE B 272
ARG B 330
TRP B 146
HIS B 404
THR B 460
 None
None
None
None
HPA  B1780 (-3.6A)
 1.43A 5xiqB-2w55B:
undetectable		 5xiqB-2w55B:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_C_HFGC1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 PHE B 272
ARG B 330
TRP B 146
HIS B 404
THR B 460
 None
None
None
None
HPA  B1780 (-3.6A)
 1.41A 5xiqC-2w55B:
undetectable		 5xiqC-2w55B:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 ALA B 588
ALA B 587
ILE B 473
ALA B 592
ILE B 506
 None
 1.08A 6a5zD-2w55B:
undetectable		 6a5zD-2w55B:
7.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 ILE B 585
ALA B 588
ALA B 587
ILE B 473
ALA B 592
 None
 1.13A 6a5zD-2w55B:
undetectable		 6a5zD-2w55B:
7.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AY4_A_TPFA506_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 10 PHE B 376
TYR B 319
ALA B 373
ALA B 369
LEU B 741
 None
 1.27A 6ay4A-2w55B:
undetectable		 6ay4A-2w55B:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 VAL B 190
LEU B 100
LEU B  86
ALA B 183
LEU B  35
 None
 1.09A 6ew0B-2w55B:
undetectable		 6ew0B-2w55B:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 VAL B 190
LEU B 100
LEU B  86
ALA B 183
LEU B  35
 None
 1.08A 6ew0D-2w55B:
undetectable		 6ew0D-2w55B:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 VAL B 190
LEU B 100
LEU B  86
ALA B 183
LEU B  35
 None
 1.08A 6ew0H-2w55B:
undetectable		 6ew0H-2w55B:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 2w55 XANTHINE
DEHYDROGENASE
(Rhodobacter
capsulatus) 		5 / 12 VAL B 190
LEU B 100
LEU B  86
ALA B 183
LEU B  35
 None
 1.09A 6ew0I-2w55B:
undetectable		 6ew0I-2w55B:
6.91