SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2w57'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		3 / 3 HIS A  90
HIS A  33
HIS A  71
 ZN  A 202 (-3.5A)
ZN  A 202 (-3.3A)
ZN  A 202 ( 4.9A)
 0.69A 1rjoA-2w57A:
undetectable		 1rjoA-2w57A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		3 / 3 HIS A  90
HIS A  33
HIS A  71
 ZN  A 202 (-3.5A)
ZN  A 202 (-3.3A)
ZN  A 202 ( 4.9A)
 0.62A 1w2zA-2w57A:
undetectable		 1w2zA-2w57A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		3 / 3 HIS A  90
HIS A  33
HIS A  71
 ZN  A 202 (-3.5A)
ZN  A 202 (-3.3A)
ZN  A 202 ( 4.9A)
 0.64A 1w2zB-2w57A:
undetectable		 1w2zB-2w57A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		3 / 3 HIS A  90
HIS A  33
HIS A  71
 ZN  A 202 (-3.5A)
ZN  A 202 (-3.3A)
ZN  A 202 ( 4.9A)
 0.67A 1w2zC-2w57A:
undetectable		 1w2zC-2w57A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		3 / 3 HIS A  90
HIS A  33
HIS A  71
 ZN  A 202 (-3.5A)
ZN  A 202 (-3.3A)
ZN  A 202 ( 4.9A)
 0.67A 1w2zD-2w57A:
undetectable		 1w2zD-2w57A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_1
(RETINOIC ACID
RECEPTOR, BETA)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A  26
LEU A  23
ILE A  22
LEU A  59
LEU A  82
 None
 0.81A 1xdkF-2w57A:
undetectable		 1xdkF-2w57A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		3 / 3 HIS A  90
HIS A  33
HIS A  71
 ZN  A 202 (-3.5A)
ZN  A 202 (-3.3A)
ZN  A 202 ( 4.9A)
 0.66A 2oqeA-2w57A:
undetectable		 2oqeA-2w57A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		3 / 3 HIS A  90
HIS A  33
HIS A  71
 ZN  A 202 (-3.5A)
ZN  A 202 (-3.3A)
ZN  A 202 ( 4.9A)
 0.66A 2oqeB-2w57A:
undetectable		 2oqeB-2w57A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		3 / 3 HIS A  90
HIS A  33
HIS A  71
 ZN  A 202 (-3.5A)
ZN  A 202 (-3.3A)
ZN  A 202 ( 4.9A)
 0.68A 2oqeC-2w57A:
undetectable		 2oqeC-2w57A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		3 / 3 HIS A  90
HIS A  33
HIS A  71
 ZN  A 202 (-3.5A)
ZN  A 202 (-3.3A)
ZN  A 202 ( 4.9A)
 0.67A 2oqeD-2w57A:
undetectable		 2oqeD-2w57A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		3 / 3 HIS A  90
HIS A  33
HIS A  71
 ZN  A 202 (-3.5A)
ZN  A 202 (-3.3A)
ZN  A 202 ( 4.9A)
 0.67A 2oqeF-2w57A:
undetectable		 2oqeF-2w57A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		4 / 4 HIS A  33
GLU A 101
HIS A  90
HIS A  71
 ZN  A 202 (-3.3A)
ZN  A 202 ( 4.6A)
ZN  A 202 (-3.5A)
ZN  A 202 ( 4.9A)
 1.14A 2ozrE-2w57A:
undetectable		 2ozrE-2w57A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		4 / 7 LEU A  39
LEU A  43
LEU A  59
PRO A  18
 None
 0.82A 2vq5B-2w57A:
undetectable		 2vq5B-2w57A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		3 / 3 HIS A  90
HIS A  33
HIS A  71
 ZN  A 202 (-3.5A)
ZN  A 202 (-3.3A)
ZN  A 202 ( 4.9A)
 0.69A 2w0qA-2w57A:
undetectable		 2w0qA-2w57A:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		3 / 3 HIS A  90
HIS A  33
HIS A  71
 ZN  A 202 (-3.5A)
ZN  A 202 (-3.3A)
ZN  A 202 ( 4.9A)
 0.65A 2w0qB-2w57A:
undetectable		 2w0qB-2w57A:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_C_IBPC1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		5 / 10 THR A  16
ILE A  22
VAL A  68
GLN A  61
ARG A  19
 None
 1.11A 2wd9C-2w57A:
undetectable		 2wd9C-2w57A:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		4 / 8 PHE A  80
GLU A  38
ARG A  70
VAL A  55
 None
 1.49A 3b3pA-2w57A:
undetectable
3b3pB-2w57A:
undetectable		 3b3pA-2w57A:
16.90
3b3pB-2w57A:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		3 / 3 HIS A  90
HIS A  33
HIS A  71
 ZN  A 202 (-3.5A)
ZN  A 202 (-3.3A)
ZN  A 202 ( 4.9A)
 0.72A 3hiiA-2w57A:
undetectable		 3hiiA-2w57A:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		3 / 3 HIS A  90
HIS A  33
HIS A  71
 ZN  A 202 (-3.5A)
ZN  A 202 (-3.3A)
ZN  A 202 ( 4.9A)
 0.72A 3hiiB-2w57A:
undetectable		 3hiiB-2w57A:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		4 / 4 HIS A  86
GLU A 101
HIS A  33
LEU A  26
 None
ZN  A 202 ( 4.6A)
ZN  A 202 (-3.3A)
None
 1.47A 4m2rA-2w57A:
undetectable		 4m2rA-2w57A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		3 / 3 GLU A 101
THR A  69
HIS A  71
 ZN  A 202 ( 4.6A)
None
ZN  A 202 ( 4.9A)
 0.79A 4q15A-2w57A:
undetectable		 4q15A-2w57A:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		3 / 3 GLU A 101
THR A  69
HIS A  71
 ZN  A 202 ( 4.6A)
None
ZN  A 202 ( 4.9A)
 0.77A 4q15B-2w57A:
undetectable		 4q15B-2w57A:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		3 / 3 GLU A 101
THR A  69
HIS A  71
 ZN  A 202 ( 4.6A)
None
ZN  A 202 ( 4.9A)
 0.82A 4ydqB-2w57A:
undetectable		 4ydqB-2w57A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		4 / 7 HIS A  88
ILE A 100
VAL A  99
GLN A  32
 ZN  A 202 (-3.2A)
None
None
None
 1.01A 5kkzC-2w57A:
undetectable
5kkzE-2w57A:
undetectable		 5kkzC-2w57A:
22.45
5kkzE-2w57A:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_K_ASCK1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		4 / 7 HIS A  88
ILE A 100
VAL A  99
GLN A  32
 ZN  A 202 (-3.2A)
None
None
None
 1.02A 5kkzK-2w57A:
undetectable
5kkzQ-2w57A:
undetectable		 5kkzK-2w57A:
15.68
5kkzQ-2w57A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		4 / 7 HIS A  88
ILE A 100
VAL A  99
GLN A  32
 ZN  A 202 (-3.2A)
None
None
None
 1.00A 5kkzM-2w57A:
undetectable
5kkzO-2w57A:
undetectable		 5kkzM-2w57A:
22.45
5kkzO-2w57A:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		4 / 7 PHE A  80
GLU A  38
ARG A  70
VAL A  55
 None
 1.48A 5unwA-2w57A:
undetectable
5unwB-2w57A:
undetectable		 5unwA-2w57A:
16.90
5unwB-2w57A:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2w57 FERRIC UPTAKE
REGULATION PROTEIN
(Vibrio
cholerae) 		4 / 7 PHE A  80
GLU A  38
ARG A  70
VAL A  55
 None
 1.50A 5vuyA-2w57A:
undetectable
5vuyB-2w57A:
undetectable		 5vuyA-2w57A:
16.15
5vuyB-2w57A:
16.15