SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2w61'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_B_AG2B7001_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 6 GLU A 135
ARG A 105
ASP A 132
LEU A 131
 None
 1.03A 1mt1B-2w61A:
undetectable
1mt1C-2w61A:
undetectable		 1mt1B-2w61A:
11.89
1mt1C-2w61A:
6.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 169
THR A 103
LEU A 305
GLY A 304
PHE A  52
 None
 1.42A 1v8bA-2w61A:
undetectable		 1v8bA-2w61A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 169
THR A 103
LEU A 305
GLY A 304
PHE A  52
 None
 1.43A 1v8bC-2w61A:
undetectable		 1v8bC-2w61A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 133
LEU A 131
LEU A 168
ILE A 209
SER A 164
ALA A 161
 None
 1.45A 2bxqA-2w61A:
undetectable		 2bxqA-2w61A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 8 MET A 243
PHE A 273
ALA A 291
LEU A 292
 None
 0.69A 2o01A-2w61A:
undetectable		 2o01A-2w61A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 GLU A 263
GLY A 256
PHE A 273
ILE A 241
 None
 1.00A 2qmzA-2w61A:
undetectable
2qmzB-2w61A:
undetectable		 2qmzA-2w61A:
18.57
2qmzB-2w61A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 169
THR A 103
LEU A 305
GLY A 304
PHE A  52
 None
 1.37A 2zj0A-2w61A:
undetectable		 2zj0A-2w61A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 169
THR A 103
LEU A 305
GLY A 304
PHE A  52
 None
 1.41A 3ce6A-2w61A:
undetectable		 3ce6A-2w61A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 169
THR A 103
LEU A 305
GLY A 304
PHE A  52
 None
 1.37A 3g1uA-2w61A:
undetectable		 3g1uA-2w61A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 169
THR A 103
LEU A 305
GLY A 304
PHE A  52
 None
 1.40A 3glqB-2w61A:
undetectable		 3glqB-2w61A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_A_ADNA439_1
(ADENOSYLHOMOCYSTEINA
SE)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 10 LEU A 169
THR A 103
LEU A 305
GLY A 304
PHE A  52
 None
 1.44A 3h9uA-2w61A:
undetectable		 3h9uA-2w61A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 9 MET A 119
LEU A  83
ARG A 105
SER A 164
GLY A 170
 None
 1.26A 3hcnB-2w61A:
0.0		 3hcnB-2w61A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 10 MET A 119
LEU A  83
ARG A 105
SER A 164
GLY A 170
 None
 1.27A 3hcoB-2w61A:
0.0		 3hcoB-2w61A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 4 GLY A 304
GLY A  56
THR A 103
LEU A 130
 None
 0.74A 3si7C-2w61A:
undetectable
3si7D-2w61A:
undetectable		 3si7C-2w61A:
19.10
3si7D-2w61A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_B_QMRB1214_1
(CAPITELLA TELETA
ACHBP)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 9 ILE A  57
ILE A  54
PHE A  52
VAL A 101
TYR A 128
 None
 1.36A 4afgA-2w61A:
0.0
4afgE-2w61A:
0.0		 4afgA-2w61A:
16.79
4afgE-2w61A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 GLY A 212
VAL A 211
PHE A  43
ILE A  38
 None
 0.92A 4fglC-2w61A:
undetectable		 4fglC-2w61A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 169
THR A 103
LEU A 305
GLY A 304
PHE A  52
 None
 1.42A 4lvcA-2w61A:
undetectable		 4lvcA-2w61A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 418
SER A 416
LEU A 468
ASN A 144
 None
 1.04A 4n09B-2w61A:
2.9		 4n09B-2w61A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 5 ASN A 295
GLY A 294
ASP A  45
ASP A 344
 None
 1.11A 4n48B-2w61A:
undetectable		 4n48B-2w61A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 4 ASN A 295
GLY A 294
ASP A  45
ASP A 344
 None
 1.12A 4n49A-2w61A:
undetectable		 4n49A-2w61A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ASN A 141
PRO A 145
PHE A 189
TYR A 155
 None
 1.27A 4v2yA-2w61A:
0.0		 4v2yA-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_B_EF2B151_1
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ASN A 141
PRO A 145
PHE A 189
TYR A 155
 None
 1.33A 4v2yB-2w61A:
undetectable		 4v2yB-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_C_EF2C151_1
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ASN A 141
PRO A 145
PHE A 189
TYR A 155
 None
 1.14A 4v2yC-2w61A:
0.0		 4v2yC-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_C_EF2C151_1
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ASN A 141
PRO A 145
PHE A 189
TYR A 213
 None
 1.18A 4v2yC-2w61A:
0.0		 4v2yC-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_A_Y70A151_1
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ASN A 141
PRO A 145
PHE A 189
TYR A 155
 None
 1.28A 4v2zA-2w61A:
0.0		 4v2zA-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 141
PRO A 145
PHE A 189
TYR A 155
 None
 1.28A 4v2zB-2w61A:
undetectable		 4v2zB-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 141
PRO A 145
PHE A 189
TYR A 155
 None
 1.16A 4v2zC-2w61A:
undetectable		 4v2zC-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 141
PRO A 145
PHE A 189
TYR A 213
 None
 1.19A 4v2zC-2w61A:
undetectable		 4v2zC-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_A_LVYA151_1
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ASN A 141
PRO A 145
PHE A 189
TYR A 155
 None
 1.26A 4v30A-2w61A:
0.0		 4v30A-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 141
PRO A 145
PHE A 189
TYR A 155
 None
 1.18A 4v30B-2w61A:
undetectable		 4v30B-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 244
TYR A 257
GLU A 275
ASP A 132
 None
 1.49A 4x61A-2w61A:
2.3		 4x61A-2w61A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMH_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ASN A 141
PRO A 145
PHE A 189
TYR A 155
 None
 1.08A 5amhA-2w61A:
0.0		 5amhA-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMH_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ASN A 141
PRO A 145
PHE A 189
TYR A 213
 None
 1.28A 5amhA-2w61A:
0.0		 5amhA-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ASN A 141
PRO A 145
PHE A 189
TYR A 155
 None
 1.30A 5amiA-2w61A:
0.0		 5amiA-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 141
PRO A 145
PHE A 189
TYR A 155
 None
 1.32A 5amiB-2w61A:
undetectable		 5amiB-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ASN A 141
PRO A 145
PHE A 189
TYR A 155
 None
 1.27A 5amjA-2w61A:
0.0		 5amjA-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_B_EF2B151_1
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ASN A 141
PRO A 145
PHE A 189
TYR A 155
 None
 1.28A 5amjB-2w61A:
undetectable		 5amjB-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 141
PRO A 145
PHE A 189
TYR A 155
 None
 1.39A 5amkA-2w61A:
undetectable		 5amkA-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_B_EF2B151_1
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ASN A 141
PRO A 145
PHE A 189
TYR A 155
 None
 1.26A 5amkB-2w61A:
0.0		 5amkB-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 209
VAL A 230
PHE A 229
ILE A 194
 None
 1.00A 5hieC-2w61A:
undetectable		 5hieC-2w61A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 8 SER A 146
ASP A 148
TYR A 155
ASN A 141
 None
 1.13A 5l1fA-2w61A:
undetectable
5l1fB-2w61A:
undetectable		 5l1fA-2w61A:
22.01
5l1fB-2w61A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 169
THR A 103
LEU A 305
GLY A 304
PHE A  52
 None
 1.46A 5m66B-2w61A:
undetectable		 5m66B-2w61A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 304
PHE A 238
SER A 274
TYR A 107
ALA A  58
 None
 1.17A 5n0oA-2w61A:
undetectable		 5n0oA-2w61A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 304
SER A 274
PHE A 172
TYR A 107
ALA A  58
 None
 1.12A 5n0oA-2w61A:
undetectable		 5n0oA-2w61A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 304
SER A 274
PHE A 172
TYR A 107
ALA A  58
 None
 1.12A 5n0oB-2w61A:
undetectable		 5n0oB-2w61A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_A_EF2A202_0
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ASN A 141
PRO A 145
PHE A 189
TYR A 155
 None
 1.25A 5oh1A-2w61A:
0.0		 5oh1A-2w61A:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ASN A 141
PRO A 145
PHE A 189
TYR A 155
 None
 1.29A 5oh1B-2w61A:
undetectable		 5oh1B-2w61A:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 141
PRO A 145
PHE A 189
TYR A 155
 None
 1.05A 5oh1C-2w61A:
undetectable		 5oh1C-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 141
PRO A 145
PHE A 189
TYR A 213
 None
 1.22A 5oh1C-2w61A:
undetectable		 5oh1C-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_A_9V2A202_0
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ASN A 141
PRO A 145
PHE A 189
TYR A 155
 None
 1.23A 5oh3A-2w61A:
0.0		 5oh3A-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_B_9V2B202_0
(CEREBLON ISOFORM 4)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ASN A 141
PRO A 145
PHE A 189
TYR A 155
 None
 1.32A 5oh3B-2w61A:
0.0		 5oh3B-2w61A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 207
PRO A 210
TYR A 128
 None
 0.96A 5tzoB-2w61A:
undetectable		 5tzoB-2w61A:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_1
(ADENOSYLHOMOCYSTEINA
SE)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 169
THR A 103
LEU A 305
GLY A 304
PHE A  52
 None
 1.50A 5utuH-2w61A:
undetectable		 5utuH-2w61A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 168
GLY A 170
THR A  33
MET A 162
ALA A 161
 None
 1.15A 5x5qB-2w61A:
undetectable		 5x5qB-2w61A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_1
(-)		 2w61 GLYCOLIPID-ANCHORED
SURFACE PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 169
THR A 103
LEU A 305
GLY A 304
PHE A  52
 None
 1.41A 6gbnA-2w61A:
undetectable		 6gbnA-2w61A:
20.52