SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2w6d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 7 LEU A  49
ALA A  38
LEU A  51
THR A  34
 None
 0.73A 1dvxB-2w6dA:
undetectable		 1dvxB-2w6dA:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		5 / 12 LEU A 549
ASN A 546
LEU A 548
ALA A 457
LEU A 461
 None
 1.19A 1gs4A-2w6dA:
undetectable		 1gs4A-2w6dA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 7 THR A  84
LEU A  94
GLY A  91
LEU A 300
 GDP  A1696 (-3.8A)
None
None
None
 1.03A 1gtiE-2w6dA:
undetectable		 1gtiE-2w6dA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 6 LEU A  49
ALA A  38
LEU A  51
THR A  34
 None
 0.80A 1ictB-2w6dA:
undetectable		 1ictB-2w6dA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 8 LEU A 231
SER A  62
ASN A  64
ASP A  57
 None
 1.11A 1ig3A-2w6dA:
undetectable
1ig3B-2w6dA:
undetectable		 1ig3A-2w6dA:
18.08
1ig3B-2w6dA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 6 LEU A  49
ALA A  38
LEU A  51
THR A  34
 None
 0.72A 1tyrA-2w6dA:
undetectable		 1tyrA-2w6dA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 5 ALA A 156
ALA A 104
TYR A 139
GLN A 128
 None
 1.06A 1xl6A-2w6dA:
2.5
1xl6B-2w6dA:
3.2		 1xl6A-2w6dA:
17.70
1xl6B-2w6dA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		5 / 12 LEU A  28
ASN A  29
LEU A  31
ALA A  32
LEU A 338
 None
 1.19A 2aa6A-2w6dA:
undetectable		 2aa6A-2w6dA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 8 ARG A 299
SER A 292
LEU A 205
LEU A 171
 None
GDP  A1696 (-4.6A)
None
None
 0.97A 2bfpB-2w6dA:
undetectable		 2bfpB-2w6dA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 8 SER A 626
PHE A 624
ALA A 470
ASP A 543
 None
 0.91A 2bxkA-2w6dA:
3.7		 2bxkA-2w6dA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		3 / 3 PHE A 385
VAL A 631
TRP A 517
 None
 0.81A 2cc8A-2w6dA:
undetectable		 2cc8A-2w6dA:
7.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		3 / 3 PHE A 385
VAL A 631
TRP A 517
 None
 0.80A 2ccbA-2w6dA:
undetectable		 2ccbA-2w6dA:
7.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		5 / 12 ALA A  88
VAL A  74
ASP A 180
GLY A  91
ILE A  90
 None
 1.25A 2dcfA-2w6dA:
undetectable		 2dcfA-2w6dA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		5 / 12 LEU A 549
ASN A 546
LEU A 548
ALA A 457
LEU A 461
 None
 1.15A 2oz7A-2w6dA:
undetectable		 2oz7A-2w6dA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_CHDA332_0
(CHOLOYLGLYCINE
HYDROLASE)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		5 / 12 THR A 565
ASN A 427
ILE A 561
ILE A 452
LEU A 426
 CPL  A1705 (-3.7A)
None
CPL  A1705 (-1.2A)
CPL  A1705 ( 4.8A)
CPL  A1708 (-4.9A)
 1.17A 2rlcA-2w6dA:
undetectable		 2rlcA-2w6dA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		5 / 6 LEU A  49
GLU A 663
ALA A  38
LEU A  51
THR A  34
 None
 1.26A 2roxB-2w6dA:
undetectable		 2roxB-2w6dA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		3 / 3 PHE A 385
VAL A 631
TRP A 517
 None
 0.79A 2vx9A-2w6dA:
undetectable		 2vx9A-2w6dA:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		3 / 3 GLU A  15
ASP A  13
TYR A 691
 None
 0.86A 2yvlB-2w6dA:
undetectable		 2yvlB-2w6dA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 4 THR A 565
VAL A 608
GLY A 556
THR A 553
 CPL  A1705 (-3.7A)
None
None
None
 1.09A 3cflA-2w6dA:
undetectable		 3cflA-2w6dA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 6 LEU A  49
ALA A  38
LEU A  51
THR A  34
 None
 0.76A 3cfqA-2w6dA:
undetectable		 3cfqA-2w6dA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 7 LEU A  49
ALA A  38
LEU A  51
THR A  34
 None
 0.76A 3cfqA-2w6dA:
undetectable
3cfqB-2w6dA:
undetectable		 3cfqA-2w6dA:
11.41
3cfqB-2w6dA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 7 LEU A  49
ALA A  38
LEU A  51
THR A  34
 None
 0.77A 3d2tA-2w6dA:
undetectable		 3d2tA-2w6dA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_A_C2FA995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		5 / 12 LEU A  28
GLN A 334
LEU A 338
LEU A  65
ARG A  21
 None
 1.39A 3fsuA-2w6dA:
2.5		 3fsuA-2w6dA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		3 / 3 ASN A 659
ASN A 362
GLU A 358
 None
 0.91A 3kpdB-2w6dA:
undetectable		 3kpdB-2w6dA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_A_VIBA223_1
(THIAMINE
PYROPHOSPHOKINASE)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 7 LEU A 231
SER A  62
ASN A  64
ASP A  57
 None
 1.04A 3lm8A-2w6dA:
undetectable
3lm8C-2w6dA:
undetectable		 3lm8A-2w6dA:
15.88
3lm8C-2w6dA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_A_VIBA223_1
(THIAMINE
PYROPHOSPHOKINASE)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 7 LEU A 338
SER A  62
ASN A  64
ASP A  57
 None
 0.81A 3lm8A-2w6dA:
undetectable
3lm8C-2w6dA:
undetectable		 3lm8A-2w6dA:
15.88
3lm8C-2w6dA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 8 ASP A  57
LEU A 338
SER A  62
ASN A  64
 None
 0.88A 3lm8B-2w6dA:
undetectable
3lm8D-2w6dA:
undetectable		 3lm8B-2w6dA:
15.88
3lm8D-2w6dA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 7 LEU A  49
ALA A  38
LEU A  51
THR A  34
 None
 0.86A 3ozkB-2w6dA:
undetectable		 3ozkB-2w6dA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 7 LEU A  49
ALA A  38
LEU A  51
THR A  34
 None
 0.89A 4d7bA-2w6dA:
undetectable		 4d7bA-2w6dA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		3 / 3 ARG A 264
TYR A 274
ASN A 281
 None
 0.67A 4ffwB-2w6dA:
undetectable		 4ffwB-2w6dA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 6 LEU A  49
ALA A  38
LEU A  51
THR A  34
 None
 0.73A 4i89A-2w6dA:
undetectable		 4i89A-2w6dA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 6 LEU A  49
ALA A  38
LEU A  51
THR A  34
 None
 0.83A 4ikiB-2w6dA:
undetectable		 4ikiB-2w6dA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 7 LEU A  49
ALA A  38
LEU A  51
THR A  34
 None
 0.91A 4ikjA-2w6dA:
undetectable
4ikjB-2w6dA:
undetectable		 4ikjA-2w6dA:
12.22
4ikjB-2w6dA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 8 LEU A  49
ALA A  38
LEU A  51
THR A  34
 None
 0.90A 4ikjA-2w6dA:
undetectable
4ikjB-2w6dA:
undetectable		 4ikjA-2w6dA:
12.22
4ikjB-2w6dA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 8 LEU A  49
ALA A  38
LEU A  51
THR A  34
 None
 0.84A 4ikkA-2w6dA:
undetectable
4ikkB-2w6dA:
undetectable		 4ikkA-2w6dA:
12.22
4ikkB-2w6dA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 7 LEU A  49
ALA A  38
LEU A  51
THR A  34
 None
 0.86A 4ikkA-2w6dA:
undetectable
4ikkB-2w6dA:
undetectable		 4ikkA-2w6dA:
12.22
4ikkB-2w6dA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 7 LEU A  49
ALA A  38
LEU A  51
THR A  34
 None
 0.82A 4iklA-2w6dA:
undetectable
4iklB-2w6dA:
undetectable		 4iklA-2w6dA:
12.22
4iklB-2w6dA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 8 LEU A  49
ALA A  38
LEU A  51
THR A  34
 None
 0.81A 4iklA-2w6dA:
undetectable
4iklB-2w6dA:
undetectable		 4iklA-2w6dA:
12.22
4iklB-2w6dA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		3 / 3 GLU A 622
ILE A 389
ALA A 397
 None
 0.59A 4wnwB-2w6dA:
2.1		 4wnwB-2w6dA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		3 / 3 GLU A 464
LYS A 545
ASN A 550
 None
 1.01A 4y1dA-2w6dA:
undetectable
4y1dD-2w6dA:
undetectable		 4y1dA-2w6dA:
13.39
4y1dD-2w6dA:
0.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 6 LEU A  49
ALA A  38
LEU A  51
THR A  34
 None
 0.70A 5bojA-2w6dA:
undetectable		 5bojA-2w6dA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		3 / 3 ALA A  61
ASN A  64
LEU A  65
 None
 0.47A 5i1oA-2w6dA:
undetectable		 5i1oA-2w6dA:
5.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 6 LEU A  49
ALA A  38
LEU A  51
THR A  34
 None
 0.67A 5l4iA-2w6dA:
undetectable		 5l4iA-2w6dA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 6 LEU A  49
ALA A  38
LEU A  51
THR A  34
 None
 0.68A 5l4iB-2w6dA:
undetectable		 5l4iB-2w6dA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 5 TYR A 422
ARG A 421
THR A 414
LEU A 411
 None
CPL  A1701 (-4.4A)
CPL  A1701 (-1.4A)
None
 1.22A 5x19J-2w6dA:
undetectable		 5x19J-2w6dA:
7.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 5 TYR A 422
ARG A 421
THR A 414
LEU A 411
 None
CPL  A1701 (-4.4A)
CPL  A1701 (-1.4A)
None
 1.26A 5x1bJ-2w6dA:
undetectable		 5x1bJ-2w6dA:
7.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		3 / 3 ALA A 163
PHE A 121
GLN A 128
 None
 0.83A 6eceA-2w6dA:
2.3		 6eceA-2w6dA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H3D_A_DHIA601_0
(DUF2338
DOMAIN-CONTAINING
PROTEIN)		 2w6d DYNAMIN FAMILY
PROTEIN
(Nostoc
punctiforme) 		4 / 5 TYR A 274
ASN A 224
TYR A 221
PHE A 206
 None
 1.47A 6h3dA-2w6dA:
2.0		 6h3dA-2w6dA:
20.67