SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2w7q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 2w7q OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 THR A 106
PRO A 109
THR A 108
 None
 0.87A 1dscC-2w7qA:
undetectable		 1dscC-2w7qA:
4.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 2w7q OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 THR A 108
THR A 106
PRO A 109
 None
 0.82A 1dscC-2w7qA:
undetectable		 1dscC-2w7qA:
4.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 2w7q OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 THR A 108
THR A 106
PRO A 109
 None
 0.89A 1fjaC-2w7qA:
undetectable		 1fjaC-2w7qA:
4.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 2w7q OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 THR A 108
THR A 106
PRO A 109
 None
 0.88A 1fjaD-2w7qA:
undetectable		 1fjaD-2w7qA:
4.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 2w7q OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 THR A 106
PRO A 109
THR A 108
 None
 0.85A 1mnvD-2w7qA:
undetectable		 1mnvD-2w7qA:
4.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 2w7q OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 THR A 106
PRO A 109
THR A 108
 None
 0.88A 1ovfB-2w7qA:
undetectable		 1ovfB-2w7qA:
4.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 2w7q OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 THR A 108
THR A 106
PRO A 109
 None
 0.81A 1unjW-2w7qA:
undetectable		 1unjW-2w7qA:
4.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 2w7q OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 THR A 106
PRO A 109
THR A 108
 None
 0.85A 1unmE-2w7qA:
undetectable		 1unmE-2w7qA:
4.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 2w7q OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 THR A 108
THR A 106
PRO A 109
 None
 0.85A 1unmE-2w7qA:
undetectable		 1unmE-2w7qA:
4.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 2w7q OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  30
ASN A  31
LEU A  29
MET A 182
LEU A  36
 None
 1.45A 2q7kA-2w7qA:
undetectable		 2q7kA-2w7qA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 2w7q OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 SER A  41
THR A  71
PHE A  67
 None
 0.73A 2x91A-2w7qA:
undetectable		 2x91A-2w7qA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 2w7q OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 PHE A  67
GLY A  65
ILE A  80
ASN A  82
LEU A 111
 None
 0.99A 2zzmA-2w7qA:
undetectable		 2zzmA-2w7qA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 2w7q OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 THR A 106
PRO A 109
THR A 108
 None
 0.87A 316dC-2w7qA:
undetectable		 316dC-2w7qA:
4.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 2w7q OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 PHE A  67
GLY A  65
ILE A  80
ASN A  82
LEU A 111
 None
 0.99A 3ay0B-2w7qA:
undetectable		 3ay0B-2w7qA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IM2_A_BEZA401_0
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL)		 2w7q OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 180
PRO A 109
LEU A 113
LEU A 153
VAL A 160
 None
 1.17A 5im2A-2w7qA:
undetectable		 5im2A-2w7qA:
22.28