SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2w82'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_I_ZPCI1318_2 (CYS-LOOP LIGAND-GATED ION CHANNEL)	2w82	ORF18 (Enterococcus faecalis)	4 / 6	GLU A 162 ILE A 105 PHE A 153 TYR A 119	None	1.20A	4a97I-2w82A: undetectable	4a97I-2w82A: 19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EOH_B_TEPB402_1 (PYRIDOXAL KINASE)	2w82	ORF18 (Enterococcus faecalis)	4 / 5	SER A 155 HIS A 107 VAL A 116 ASP A 112	None	1.49A	4eohB-2w82A: undetectable	4eohB-2w82A: 18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MME_B_29QB603_1 (TRANSPORTER)	2w82	ORF18 (Enterococcus faecalis)	5 / 9	VAL A 116 ALA A 117 GLY A 151 PHE A 153 GLY A 144	None	1.19A	4mmeB-2w82A: undetectable	4mmeB-2w82A: 13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MMF_A_29QA603_1 (TRANSPORTER)	2w82	ORF18 (Enterococcus faecalis)	5 / 9	VAL A 116 ALA A 117 TYR A 120 GLY A 151 GLY A 144	None	1.38A	4mmfA-2w82A: undetectable	4mmfA-2w82A: 13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UMW_B_RBFB201_1 (GLYOXALASE/BLEOMYCIN RESISANCE PROTEIN/DIOXYGENASE)	2w82	ORF18 (Enterococcus faecalis)	4 / 7	VAL A 130 ARG A 118 TYR A 140 GLU A 122	None	1.05A	5umwB-2w82A: undetectable 5umwE-2w82A: undetectable	5umwB-2w82A: 16.57 5umwE-2w82A: 16.57

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4A97_I_ZPCI1318_2","CYS-LOOP LIGAND-GATED ION CHANNEL","2w82","ORF18","Enterococcus faecalis",4,"GLU A 162;ILE A 105;PHE A 153;TYR A 119","None","1.20A","4a97I-2w82A:undetectable","4a97I-2w82A:19.74"],["4EOH_B_TEPB402_1","PYRIDOXAL KINASE","2w82","ORF18","Enterococcus faecalis",4,"SER A 155;HIS A 107;VAL A 116;ASP A 112","None","1.49A","4eohB-2w82A:undetectable","4eohB-2w82A:18.39"],["4MME_B_29QB603_1","TRANSPORTER","2w82","ORF18","Enterococcus faecalis",5,"VAL A 116;ALA A 117;GLY A 151;PHE A 153;GLY A 144","None","1.19A","4mmeB-2w82A:undetectable","4mmeB-2w82A:13.98"],["4MMF_A_29QA603_1","TRANSPORTER","2w82","ORF18","Enterococcus faecalis",5,"VAL A 116;ALA A 117;TYR A 120;GLY A 151;GLY A 144","None","1.38A","4mmfA-2w82A:undetectable","4mmfA-2w82A:13.98"],["5UMW_B_RBFB201_1","GLYOXALASE\/BLEOMYCIN RESISANCE PROTEIN\/DIOXYGENASE;GLYOXALASE\/BLEOMYCIN RESISANCE PROTEIN\/DIOXYGENASE","2w82","ORF18","Enterococcus faecalis",4,"VAL A 130;ARG A 118;TYR A 140;GLU A 122","None","1.05A","5umwB-2w82A:undetectable;5umwE-2w82A:undetectable","5umwB-2w82A:16.57;5umwE-2w82A:16.57"]]