SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2w8m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_1_T441128_1
(TRANSTHYRETIN)		 2w8m ORF D212
(Sulfolobus
spindle-shaped
virus
8) 		4 / 5 LEU A 157
GLU A 125
ALA A 127
LEU A 154
 None
 1.21A 1eta1-2w8mA:
undetectable		 1eta1-2w8mA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_1_T441128_1
(TRANSTHYRETIN)		 2w8m ORF D212
(Sulfolobus
spindle-shaped
virus
8) 		4 / 6 LEU A 157
GLU A 125
ALA A 127
LEU A 154
 None
 1.19A 1etb1-2w8mA:
undetectable		 1etb1-2w8mA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 2w8m ORF D212
(Sulfolobus
spindle-shaped
virus
8) 		5 / 12 PHE A 203
TYR A 206
LEU A 207
ALA A  86
TYR A  68
 None
 1.05A 5h8tA-2w8mA:
undetectable		 5h8tA-2w8mA:
21.36