SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2w8s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ERR_B_RALB600_1 (ESTROGEN RECEPTOR)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 12	THR A 193 ALA A 196 LEU A 200 LEU A 210 LEU A 102	None	0.81A	1errB-2w8sA: undetectable	1errB-2w8sA: 18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UKB_A_BEZA1301_0 (2-HYDROXY-6-OXO-7-ME THYLOCTA-2,4-DIENOAT E HYDROLASE)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 6	LEU A 308 PHE A 305 ALA A 306 LEU A 200	None	0.99A	1ukbA-2w8sA: undetectable	1ukbA-2w8sA: 20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V54_C_CHDC3525_0 (CYTOCHROME C OXIDASE POLYPEPTIDE I CYTOCHROME C OXIDASE POLYPEPTIDE III)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.27A	1v54A-2w8sA: undetectable 1v54C-2w8sA: undetectable	1v54A-2w8sA: 19.33 1v54C-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V54_P_CHDP4525_0 (CYTOCHROME C OXIDASE POLYPEPTIDE I CYTOCHROME C OXIDASE POLYPEPTIDE III)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.29A	1v54N-2w8sA: undetectable 1v54P-2w8sA: undetectable	1v54N-2w8sA: 19.33 1v54P-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V55_C_CHDC3525_0 (CYTOCHROME C OXIDASE POLYPEPTIDE I CYTOCHROME C OXIDASE POLYPEPTIDE III)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.29A	1v55A-2w8sA: undetectable 1v55C-2w8sA: undetectable	1v55A-2w8sA: 19.33 1v55C-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYR_C_CHDC525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.26A	2dyrA-2w8sA: undetectable 2dyrC-2w8sA: undetectable	2dyrA-2w8sA: 19.33 2dyrC-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYR_P_CHDP1525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.30A	2dyrN-2w8sA: undetectable 2dyrP-2w8sA: undetectable	2dyrN-2w8sA: 19.33 2dyrP-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYS_C_CHDC304_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 6	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.27A	2dysA-2w8sA: undetectable 2dysC-2w8sA: undetectable	2dysA-2w8sA: 19.33 2dysC-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYS_P_CHDP304_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 6	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.31A	2dysN-2w8sA: undetectable 2dysP-2w8sA: undetectable	2dysN-2w8sA: 19.33 2dysP-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIJ_C_CHDC525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.28A	2eijA-2w8sA: undetectable 2eijC-2w8sA: undetectable	2eijA-2w8sA: 19.33 2eijC-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIJ_P_CHDP1525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.31A	2eijN-2w8sA: undetectable 2eijP-2w8sA: undetectable	2eijN-2w8sA: 19.33 2eijP-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIK_C_CHDC525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.27A	2eikA-2w8sA: undetectable 2eikC-2w8sA: undetectable	2eikA-2w8sA: 19.33 2eikC-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIK_P_CHDP1525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.30A	2eikN-2w8sA: undetectable 2eikP-2w8sA: undetectable	2eikN-2w8sA: 19.33 2eikP-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIL_C_CHDC525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.26A	2eilA-2w8sA: undetectable 2eilC-2w8sA: undetectable	2eilA-2w8sA: 19.33 2eilC-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIL_P_CHDP1525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.29A	2eilN-2w8sA: undetectable 2eilP-2w8sA: undetectable	2eilN-2w8sA: 19.33 2eilP-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIM_A_CHDA525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 6	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.27A	2eimA-2w8sA: undetectable 2eimC-2w8sA: undetectable	2eimA-2w8sA: 19.33 2eimC-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIM_P_CHDP1525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 6	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.30A	2eimN-2w8sA: undetectable 2eimP-2w8sA: undetectable	2eimN-2w8sA: 19.33 2eimP-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIN_C_CHDC525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 6	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.27A	2einA-2w8sA: undetectable 2einC-2w8sA: undetectable	2einA-2w8sA: 19.33 2einC-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIN_P_CHDP1525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 6	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.33A	2einN-2w8sA: undetectable 2einP-2w8sA: undetectable	2einN-2w8sA: 19.33 2einP-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F8L_A_SAMA400_0 (HYPOTHETICAL PROTEIN LMO1582)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 12	GLY A 67 ASN A 88 LEU A 89 ASP A 390 LEU A 68	None	0.95A	2f8lA-2w8sA: undetectable	2f8lA-2w8sA: 20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JFA_A_RALA600_1 (ESTROGEN RECEPTOR)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 12	THR A 193 ALA A 196 LEU A 200 LEU A 210 LEU A 102	None	0.84A	2jfaA-2w8sA: undetectable	2jfaA-2w8sA: 19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PLW_A_SAMA203_1 (RIBOSOMAL RNA METHYLTRANSFERASE, PUTATIVE)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	3 / 3	SER A 63 ASP A 372 ASP A 390	None	0.78A	2plwA-2w8sA: 2.2	2plwA-2w8sA: 16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q6H_A_CXXA801_1 (TRANSPORTER)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 11	LEU A 22 ARG A 24 ILE A 19 LEU A 37 ASP A 38	None	1.28A	2q6hA-2w8sA: undetectable	2q6hA-2w8sA: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QXS_A_RALA600_1 (ESTROGEN RECEPTOR)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 12	THR A 193 ALA A 196 LEU A 200 LEU A 210 LEU A 102	None	0.88A	2qxsA-2w8sA: undetectable	2qxsA-2w8sA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QXS_B_RALB600_1 (ESTROGEN RECEPTOR)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 12	THR A 193 ALA A 196 LEU A 200 LEU A 210 LEU A 102	None	0.90A	2qxsB-2w8sA: undetectable	2qxsB-2w8sA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WEK_A_DIFA1373_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 8	PHE A 450 TYR A 412 PHE A 458 ASN A 469	None	0.97A	2wekA-2w8sA: undetectable	2wekA-2w8sA: 21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WEK_B_DIFB1373_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 8	PHE A 450 TYR A 412 PHE A 458 ASN A 469	None	0.94A	2wekB-2w8sA: undetectable	2wekB-2w8sA: 21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y69_A_CHDA1517_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.28A	2y69A-2w8sA: undetectable 2y69C-2w8sA: undetectable	2y69A-2w8sA: 19.33 2y69C-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZXW_C_CHDC525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 6	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.30A	2zxwA-2w8sA: undetectable 2zxwC-2w8sA: undetectable	2zxwA-2w8sA: 19.33 2zxwC-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZXW_P_CHDP1525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 6	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.30A	2zxwN-2w8sA: undetectable 2zxwP-2w8sA: undetectable	2zxwN-2w8sA: 19.33 2zxwP-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A51_B_VDYB6178_1 (VITAMIN D HYDROXYLASE)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 12	PRO A 386 THR A 385 LEU A 378 THR A 322 VAL A 10	None	1.33A	3a51B-2w8sA: undetectable	3a51B-2w8sA: 23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABK_C_CHDC525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.28A	3abkA-2w8sA: undetectable 3abkC-2w8sA: undetectable	3abkA-2w8sA: 19.33 3abkC-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABK_P_CHDP1525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.26A	3abkN-2w8sA: undetectable 3abkP-2w8sA: undetectable	3abkN-2w8sA: 19.33 3abkP-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABM_P_CHDP1525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.28A	3abmN-2w8sA: undetectable 3abmP-2w8sA: undetectable	3abmN-2w8sA: 19.33 3abmP-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG1_C_CHDC525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 6	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.29A	3ag1A-2w8sA: undetectable 3ag1C-2w8sA: undetectable	3ag1A-2w8sA: 19.33 3ag1C-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG1_P_CHDP1525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 6	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.28A	3ag1N-2w8sA: undetectable 3ag1P-2w8sA: undetectable	3ag1N-2w8sA: 19.33 3ag1P-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG2_A_CHDA525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.30A	3ag2A-2w8sA: undetectable 3ag2C-2w8sA: undetectable	3ag2A-2w8sA: 19.33 3ag2C-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG2_P_CHDP1525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.33A	3ag2N-2w8sA: undetectable 3ag2P-2w8sA: undetectable	3ag2N-2w8sA: 19.33 3ag2P-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG3_C_CHDC525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.28A	3ag3A-2w8sA: undetectable 3ag3C-2w8sA: undetectable	3ag3A-2w8sA: 19.33 3ag3C-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG3_P_CHDP1525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.28A	3ag3N-2w8sA: undetectable 3ag3P-2w8sA: undetectable	3ag3N-2w8sA: 19.33 3ag3P-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG4_C_CHDC525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.30A	3ag4A-2w8sA: undetectable 3ag4C-2w8sA: undetectable	3ag4A-2w8sA: 19.33 3ag4C-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG4_P_CHDP1525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.29A	3ag4N-2w8sA: undetectable 3ag4P-2w8sA: undetectable	3ag4N-2w8sA: 19.33 3ag4P-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASN_C_CHDC525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 6	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.26A	3asnA-2w8sA: undetectable 3asnC-2w8sA: undetectable	3asnA-2w8sA: 19.33 3asnC-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E23_A_SAMA221_1 (UNCHARACTERIZED PROTEIN RPA2492)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	3 / 3	TYR A 290 ASP A 17 HIS A 325	None None ZN A1515 ( 3.2A)	0.92A	3e23A-2w8sA: undetectable	3e23A-2w8sA: 18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_B_CHDB152_0 (ILEAL BILE ACID-BINDING PROTEIN)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	3 / 3	ASN A 72 HIS A 73 VAL A 76	None	0.61A	3elzB-2w8sA: undetectable	3elzB-2w8sA: 12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JUS_B_ECLB600_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 8	THR A 109 GLY A 58 ALA A 62 THR A 66	None FGL A 57 ( 2.7A) None None	0.80A	3jusB-2w8sA: undetectable	3jusB-2w8sA: 21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TGV_B_BEZB1_0 (HEME-BINDING PROTEIN HUTZ)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 6	ARG A 407 PHE A 397 PRO A 403 LEU A 394	SO4 A1517 (-4.4A) None None None	1.41A	3tgvB-2w8sA: undetectable	3tgvB-2w8sA: 14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TGV_C_BEZC1_0 (HEME-BINDING PROTEIN HUTZ)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 5	ARG A 407 PHE A 397 PRO A 403 LEU A 394	SO4 A1517 (-4.4A) None None None	1.38A	3tgvC-2w8sA: undetectable	3tgvC-2w8sA: 14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UPR_A_1KXA277_1 (HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 10	TYR A 199 ILE A 103 VAL A 135 SER A 134 ILE A 128	None	1.46A	3uprA-2w8sA: undetectable	3uprA-2w8sA: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V3N_B_MIYB2001_1 (TETX2 PROTEIN)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 8	PHE A 47 GLY A 366 GLY A 361 ASN A 357	None	0.99A	3v3nB-2w8sA: undetectable	3v3nB-2w8sA: 20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WIP_G_ACTG306_0 (ACETYLCHOLINE-BINDIN G PROTEIN)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	3 / 3	ARG A 28 ARG A 48 ASP A 17	None	1.01A	3wipG-2w8sA: undetectable 3wipH-2w8sA: undetectable	3wipG-2w8sA: 17.47 3wipH-2w8sA: 17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_J_ZPCJ1318_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 8	TYR A 340 VAL A 439 ILE A 440 GLU A 343	None	0.99A	4a97I-2w8sA: undetectable	4a97I-2w8sA: 19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_J_ZPCJ1318_2 (CYS-LOOP LIGAND-GATED ION CHANNEL)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 5	GLU A 466 GLU A 441 PHE A 458 TYR A 412	None	1.23A	4a97J-2w8sA: undetectable	4a97J-2w8sA: 19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PTH_A_FOLA201_1 (DIHYDROFOLATE REDUCTASE)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	3 / 3	ASP A 309 LEU A 308 PHE A 305	None	0.71A	4pthA-2w8sA: undetectable	4pthA-2w8sA: 15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QC6_B_KANB201_2 (BIFUNCTIONAL AAC/APH)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	3 / 3	LEU A 479 ASP A 482 TYR A 483	None	0.55A	4qc6B-2w8sA: undetectable	4qc6B-2w8sA: 15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XI3_B_29SB601_1 (ESTROGEN RECEPTOR)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 12	THR A 193 ALA A 196 LEU A 200 LEU A 210 LEU A 102	None	0.89A	4xi3B-2w8sA: undetectable	4xi3B-2w8sA: 17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XI3_C_29SC601_1 (ESTROGEN RECEPTOR)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 12	THR A 193 ALA A 196 LEU A 200 LEU A 210 LEU A 102	None	0.92A	4xi3C-2w8sA: undetectable	4xi3C-2w8sA: 17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XK8_A_PQNA844_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	MET A 129 PHE A 132 ALA A 92 LEU A 93	None	1.08A	4xk8A-2w8sA: undetectable	4xk8A-2w8sA: 21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1A_P_CHDP307_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.28A	5b1aN-2w8sA: undetectable 5b1aP-2w8sA: undetectable	5b1aN-2w8sA: 19.33 5b1aP-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1B_P_CHDP307_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.29A	5b1bN-2w8sA: undetectable 5b1bP-2w8sA: undetectable	5b1bN-2w8sA: 19.33 5b1bP-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B3S_P_CHDP301_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.29A	5b3sN-2w8sA: undetectable 5b3sP-2w8sA: undetectable	5b3sN-2w8sA: 19.33 5b3sP-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IY5_C_CHDC301_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.31A	5iy5A-2w8sA: undetectable 5iy5C-2w8sA: undetectable	5iy5A-2w8sA: 19.33 5iy5C-2w8sA: 17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L8D_B_ACTB601_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	3 / 3	THR A 277 PRO A 245 ASP A 246	None	0.83A	5l8dB-2w8sA: undetectable	5l8dB-2w8sA: 23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWU_B_ACTB601_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	3 / 3	THR A 277 PRO A 245 ASP A 246	None	0.83A	5mwuB-2w8sA: undetectable	5mwuB-2w8sA: 23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TIX_B_OQRB302_0 (SULFOTRANSFERASE)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 10	ILE A 347 LEU A 22 VAL A 350 LEU A 45 GLU A 364	None	1.30A	5tixB-2w8sA: undetectable	5tixB-2w8sA: 17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5U98_A_1KXA301_1 (HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 10	TYR A 199 ILE A 103 VAL A 135 SER A 134 ILE A 128	None	1.46A	5u98A-2w8sA: 3.4	5u98A-2w8sA: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5U98_D_1KXD301_1 (HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 10	TYR A 199 ILE A 103 VAL A 135 SER A 134 ILE A 128	None	1.47A	5u98D-2w8sA: 2.4	5u98D-2w8sA: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V1T_A_SAMA605_0 (RADICAL SAM)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 12	PHE A 209 LEU A 65 THR A 106 VAL A 135 TYR A 199	None	1.49A	5v1tA-2w8sA: undetectable	5v1tA-2w8sA: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VC0_A_RITA602_2 (CYTOCHROME P450 3A4)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	ILE A 377 LEU A 349 PHE A 47 THR A 53	None	0.78A	5vc0A-2w8sA: undetectable	5vc0A-2w8sA: 21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X19_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 6	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.28A	5x19N-2w8sA: undetectable 5x19P-2w8sA: undetectable	5x19N-2w8sA: 19.33 5x19P-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1B_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 6	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.28A	5x1bN-2w8sA: undetectable 5x1bP-2w8sA: undetectable	5x1bN-2w8sA: 19.33 5x1bP-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1F_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 6	LEU A 87 MET A 374 THR A 376 LEU A 378	None	1.05A	5x1fA-2w8sA: undetectable 5x1fJ-2w8sA: undetectable	5x1fA-2w8sA: 19.33 5x1fJ-2w8sA: 8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1F_P_CHDP305_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.32A	5x1fN-2w8sA: undetectable 5x1fP-2w8sA: undetectable	5x1fN-2w8sA: 19.33 5x1fP-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCQ_P_CHDP301_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.28A	5zcqN-2w8sA: undetectable 5zcqP-2w8sA: undetectable	5zcqN-2w8sA: 19.33 5zcqP-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_B_TA1B501_1 (TUBULIN BETA CHAIN)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 12	VAL A 373 ASP A 372 LEU A 40 LEU A 37 LEU A 398	None	1.01A	6ew0B-2w8sA: undetectable	6ew0B-2w8sA: 9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_D_TA1D501_1 (TUBULIN BETA CHAIN)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 12	VAL A 373 ASP A 372 LEU A 40 LEU A 37 LEU A 398	None	1.01A	6ew0D-2w8sA: undetectable	6ew0D-2w8sA: 9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_H_TA1H501_1 (TUBULIN BETA CHAIN)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 12	VAL A 373 ASP A 372 LEU A 40 LEU A 37 LEU A 398	None	1.01A	6ew0H-2w8sA: undetectable	6ew0H-2w8sA: 9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_I_TA1I501_1 (TUBULIN BETA CHAIN)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 12	VAL A 373 ASP A 372 LEU A 40 LEU A 37 LEU A 398	None	1.01A	6ew0I-2w8sA: undetectable	6ew0I-2w8sA: 9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNF_C_QPSC602_1 (-)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 10	GLY A 336 TYR A 290 TRP A 14 HIS A 325 VAL A 55	None None None ZN A1515 ( 3.2A) None	1.33A	6gnfC-2w8sA: undetectable	6gnfC-2w8sA: 20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNG_A_QPSA601_2 (-)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 12	GLY A 336 TYR A 290 TRP A 14 HIS A 325 VAL A 55	None None None ZN A1515 ( 3.2A) None	1.37A	6gngA-2w8sA: undetectable	6gngA-2w8sA: 22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNG_B_QPSB601_1 (-)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	5 / 12	TYR A 290 TRP A 14 HIS A 325 VAL A 55 GLY A 339	None None ZN A1515 ( 3.2A) None None	1.47A	6gngB-2w8sA: undetectable	6gngB-2w8sA: 22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NKN_C_CHDC301_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 6	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.31A	6nknA-2w8sA: undetectable 6nknC-2w8sA: undetectable	6nknA-2w8sA: 19.33 6nknC-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMP_C_CHDC303_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 6	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.27A	6nmpA-2w8sA: undetectable 6nmpC-2w8sA: undetectable	6nmpA-2w8sA: 19.33 6nmpC-2w8sA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMP_P_CHDP302_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	2w8s	PHOSPHONATE MONOESTER HYDROLASE (Paraburkholderia caryophylli)	4 / 7	HIS A 411 ASP A 482 TYR A 447 HIS A 494	None None None SO4 A1517 (-4.1A)	1.31A	6nmpN-2w8sA: undetectable 6nmpP-2w8sA: undetectable	6nmpN-2w8sA: 19.33 6nmpP-2w8sA: 17.78

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ERR_B_RALB600_1","ESTROGEN RECEPTOR","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"THR A 193;ALA A 196;LEU A 200;LEU A 210;LEU A 102","None","0.81A","1errB-2w8sA:undetectable","1errB-2w8sA:18.92"],["1UKB_A_BEZA1301_0","2-HYDROXY-6-OXO-7-METHYLOCTA-2,4-DIENOATE HYDROLASE","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"LEU A 308;PHE A 305;ALA A 306;LEU A 200","None","0.99A","1ukbA-2w8sA:undetectable","1ukbA-2w8sA:20.30"],["1V54_C_CHDC3525_0","CYTOCHROME C OXIDASE POLYPEPTIDE I;CYTOCHROME C OXIDASE POLYPEPTIDE III","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.27A","1v54A-2w8sA:undetectable;1v54C-2w8sA:undetectable","1v54A-2w8sA:19.33;1v54C-2w8sA:17.78"],["1V54_P_CHDP4525_0","CYTOCHROME C OXIDASE POLYPEPTIDE I;CYTOCHROME C OXIDASE POLYPEPTIDE III","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.29A","1v54N-2w8sA:undetectable;1v54P-2w8sA:undetectable","1v54N-2w8sA:19.33;1v54P-2w8sA:17.78"],["1V55_C_CHDC3525_0","CYTOCHROME C OXIDASE POLYPEPTIDE I;CYTOCHROME C OXIDASE POLYPEPTIDE III","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.29A","1v55A-2w8sA:undetectable;1v55C-2w8sA:undetectable","1v55A-2w8sA:19.33;1v55C-2w8sA:17.78"],["2DYR_C_CHDC525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.26A","2dyrA-2w8sA:undetectable;2dyrC-2w8sA:undetectable","2dyrA-2w8sA:19.33;2dyrC-2w8sA:17.78"],["2DYR_P_CHDP1525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.30A","2dyrN-2w8sA:undetectable;2dyrP-2w8sA:undetectable","2dyrN-2w8sA:19.33;2dyrP-2w8sA:17.78"],["2DYS_C_CHDC304_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.27A","2dysA-2w8sA:undetectable;2dysC-2w8sA:undetectable","2dysA-2w8sA:19.33;2dysC-2w8sA:17.78"],["2DYS_P_CHDP304_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.31A","2dysN-2w8sA:undetectable;2dysP-2w8sA:undetectable","2dysN-2w8sA:19.33;2dysP-2w8sA:17.78"],["2EIJ_C_CHDC525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.28A","2eijA-2w8sA:undetectable;2eijC-2w8sA:undetectable","2eijA-2w8sA:19.33;2eijC-2w8sA:17.78"],["2EIJ_P_CHDP1525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.31A","2eijN-2w8sA:undetectable;2eijP-2w8sA:undetectable","2eijN-2w8sA:19.33;2eijP-2w8sA:17.78"],["2EIK_C_CHDC525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.27A","2eikA-2w8sA:undetectable;2eikC-2w8sA:undetectable","2eikA-2w8sA:19.33;2eikC-2w8sA:17.78"],["2EIK_P_CHDP1525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.30A","2eikN-2w8sA:undetectable;2eikP-2w8sA:undetectable","2eikN-2w8sA:19.33;2eikP-2w8sA:17.78"],["2EIL_C_CHDC525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.26A","2eilA-2w8sA:undetectable;2eilC-2w8sA:undetectable","2eilA-2w8sA:19.33;2eilC-2w8sA:17.78"],["2EIL_P_CHDP1525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.29A","2eilN-2w8sA:undetectable;2eilP-2w8sA:undetectable","2eilN-2w8sA:19.33;2eilP-2w8sA:17.78"],["2EIM_A_CHDA525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.27A","2eimA-2w8sA:undetectable;2eimC-2w8sA:undetectable","2eimA-2w8sA:19.33;2eimC-2w8sA:17.78"],["2EIM_P_CHDP1525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.30A","2eimN-2w8sA:undetectable;2eimP-2w8sA:undetectable","2eimN-2w8sA:19.33;2eimP-2w8sA:17.78"],["2EIN_C_CHDC525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.27A","2einA-2w8sA:undetectable;2einC-2w8sA:undetectable","2einA-2w8sA:19.33;2einC-2w8sA:17.78"],["2EIN_P_CHDP1525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.33A","2einN-2w8sA:undetectable;2einP-2w8sA:undetectable","2einN-2w8sA:19.33;2einP-2w8sA:17.78"],["2F8L_A_SAMA400_0","HYPOTHETICAL PROTEIN LMO1582","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"GLY A  67;ASN A  88;LEU A  89;ASP A 390;LEU A  68","None","0.95A","2f8lA-2w8sA:undetectable","2f8lA-2w8sA:20.29"],["2JFA_A_RALA600_1","ESTROGEN RECEPTOR","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"THR A 193;ALA A 196;LEU A 200;LEU A 210;LEU A 102","None","0.84A","2jfaA-2w8sA:undetectable","2jfaA-2w8sA:19.12"],["2PLW_A_SAMA203_1","RIBOSOMAL RNA METHYLTRANSFERASE, PUTATIVE","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",3,"SER A  63;ASP A 372;ASP A 390","None","0.78A","2plwA-2w8sA:2.2","2plwA-2w8sA:16.38"],["2Q6H_A_CXXA801_1","TRANSPORTER","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"LEU A  22;ARG A  24;ILE A  19;LEU A  37;ASP A  38","None","1.28A","2q6hA-2w8sA:undetectable","2q6hA-2w8sA:22.13"],["2QXS_A_RALA600_1","ESTROGEN RECEPTOR","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"THR A 193;ALA A 196;LEU A 200;LEU A 210;LEU A 102","None","0.88A","2qxsA-2w8sA:undetectable","2qxsA-2w8sA:18.33"],["2QXS_B_RALB600_1","ESTROGEN RECEPTOR","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"THR A 193;ALA A 196;LEU A 200;LEU A 210;LEU A 102","None","0.90A","2qxsB-2w8sA:undetectable","2qxsB-2w8sA:18.33"],["2WEK_A_DIFA1373_1","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"PHE A 450;TYR A 412;PHE A 458;ASN A 469","None","0.97A","2wekA-2w8sA:undetectable","2wekA-2w8sA:21.47"],["2WEK_B_DIFB1373_1","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"PHE A 450;TYR A 412;PHE A 458;ASN A 469","None","0.94A","2wekB-2w8sA:undetectable","2wekB-2w8sA:21.47"],["2Y69_A_CHDA1517_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.28A","2y69A-2w8sA:undetectable;2y69C-2w8sA:undetectable","2y69A-2w8sA:19.33;2y69C-2w8sA:17.78"],["2ZXW_C_CHDC525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.30A","2zxwA-2w8sA:undetectable;2zxwC-2w8sA:undetectable","2zxwA-2w8sA:19.33;2zxwC-2w8sA:17.78"],["2ZXW_P_CHDP1525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.30A","2zxwN-2w8sA:undetectable;2zxwP-2w8sA:undetectable","2zxwN-2w8sA:19.33;2zxwP-2w8sA:17.78"],["3A51_B_VDYB6178_1","VITAMIN D HYDROXYLASE","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"PRO A 386;THR A 385;LEU A 378;THR A 322;VAL A  10","None","1.33A","3a51B-2w8sA:undetectable","3a51B-2w8sA:23.26"],["3ABK_C_CHDC525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.28A","3abkA-2w8sA:undetectable;3abkC-2w8sA:undetectable","3abkA-2w8sA:19.33;3abkC-2w8sA:17.78"],["3ABK_P_CHDP1525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.26A","3abkN-2w8sA:undetectable;3abkP-2w8sA:undetectable","3abkN-2w8sA:19.33;3abkP-2w8sA:17.78"],["3ABM_P_CHDP1525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.28A","3abmN-2w8sA:undetectable;3abmP-2w8sA:undetectable","3abmN-2w8sA:19.33;3abmP-2w8sA:17.78"],["3AG1_C_CHDC525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.29A","3ag1A-2w8sA:undetectable;3ag1C-2w8sA:undetectable","3ag1A-2w8sA:19.33;3ag1C-2w8sA:17.78"],["3AG1_P_CHDP1525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.28A","3ag1N-2w8sA:undetectable;3ag1P-2w8sA:undetectable","3ag1N-2w8sA:19.33;3ag1P-2w8sA:17.78"],["3AG2_A_CHDA525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.30A","3ag2A-2w8sA:undetectable;3ag2C-2w8sA:undetectable","3ag2A-2w8sA:19.33;3ag2C-2w8sA:17.78"],["3AG2_P_CHDP1525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.33A","3ag2N-2w8sA:undetectable;3ag2P-2w8sA:undetectable","3ag2N-2w8sA:19.33;3ag2P-2w8sA:17.78"],["3AG3_C_CHDC525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.28A","3ag3A-2w8sA:undetectable;3ag3C-2w8sA:undetectable","3ag3A-2w8sA:19.33;3ag3C-2w8sA:17.78"],["3AG3_P_CHDP1525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.28A","3ag3N-2w8sA:undetectable;3ag3P-2w8sA:undetectable","3ag3N-2w8sA:19.33;3ag3P-2w8sA:17.78"],["3AG4_C_CHDC525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.30A","3ag4A-2w8sA:undetectable;3ag4C-2w8sA:undetectable","3ag4A-2w8sA:19.33;3ag4C-2w8sA:17.78"],["3AG4_P_CHDP1525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.29A","3ag4N-2w8sA:undetectable;3ag4P-2w8sA:undetectable","3ag4N-2w8sA:19.33;3ag4P-2w8sA:17.78"],["3ASN_C_CHDC525_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.26A","3asnA-2w8sA:undetectable;3asnC-2w8sA:undetectable","3asnA-2w8sA:19.33;3asnC-2w8sA:17.78"],["3E23_A_SAMA221_1","UNCHARACTERIZED PROTEIN RPA2492","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",3,"TYR A 290;ASP A  17;HIS A 325","None;None; ZN A1515 ( 3.2A)","0.92A","3e23A-2w8sA:undetectable","3e23A-2w8sA:18.01"],["3ELZ_B_CHDB152_0","ILEAL BILE ACID-BINDING PROTEIN","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",3,"ASN A  72;HIS A  73;VAL A  76","None","0.61A","3elzB-2w8sA:undetectable","3elzB-2w8sA:12.94"],["3JUS_B_ECLB600_1","LANOSTEROL 14-ALPHA DEMETHYLASE","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"THR A 109;GLY A  58;ALA A  62;THR A  66","None;FGL A  57 ( 2.7A);None;None","0.80A","3jusB-2w8sA:undetectable","3jusB-2w8sA:21.70"],["3TGV_B_BEZB1_0","HEME-BINDING PROTEIN HUTZ","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"ARG A 407;PHE A 397;PRO A 403;LEU A 394","SO4 A1517 (-4.4A);None;None;None","1.41A","3tgvB-2w8sA:undetectable","3tgvB-2w8sA:14.55"],["3TGV_C_BEZC1_0","HEME-BINDING PROTEIN HUTZ","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"ARG A 407;PHE A 397;PRO A 403;LEU A 394","SO4 A1517 (-4.4A);None;None;None","1.38A","3tgvC-2w8sA:undetectable","3tgvC-2w8sA:14.55"],["3UPR_A_1KXA277_1","HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"TYR A 199;ILE A 103;VAL A 135;SER A 134;ILE A 128","None","1.46A","3uprA-2w8sA:undetectable","3uprA-2w8sA:20.85"],["3V3N_B_MIYB2001_1","TETX2 PROTEIN","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"PHE A  47;GLY A 366;GLY A 361;ASN A 357","None","0.99A","3v3nB-2w8sA:undetectable","3v3nB-2w8sA:20.68"],["3WIP_G_ACTG306_0","ACETYLCHOLINE-BINDING PROTEIN","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",3,"ARG A  28;ARG A  48;ASP A  17","None","1.01A","3wipG-2w8sA:undetectable;3wipH-2w8sA:undetectable","3wipG-2w8sA:17.47;3wipH-2w8sA:17.47"],["4A97_J_ZPCJ1318_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"TYR A 340;VAL A 439;ILE A 440;GLU A 343","None","0.99A","4a97I-2w8sA:undetectable","4a97I-2w8sA:19.39"],["4A97_J_ZPCJ1318_2","CYS-LOOP LIGAND-GATED ION CHANNEL","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"GLU A 466;GLU A 441;PHE A 458;TYR A 412","None","1.23A","4a97J-2w8sA:undetectable","4a97J-2w8sA:19.39"],["4PTH_A_FOLA201_1","DIHYDROFOLATE REDUCTASE","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",3,"ASP A 309;LEU A 308;PHE A 305","None","0.71A","4pthA-2w8sA:undetectable","4pthA-2w8sA:15.31"],["4QC6_B_KANB201_2","BIFUNCTIONAL AAC\/APH","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",3,"LEU A 479;ASP A 482;TYR A 483","None","0.55A","4qc6B-2w8sA:undetectable","4qc6B-2w8sA:15.38"],["4XI3_B_29SB601_1","ESTROGEN RECEPTOR","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"THR A 193;ALA A 196;LEU A 200;LEU A 210;LEU A 102","None","0.89A","4xi3B-2w8sA:undetectable","4xi3B-2w8sA:17.84"],["4XI3_C_29SC601_1","ESTROGEN RECEPTOR","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"THR A 193;ALA A 196;LEU A 200;LEU A 210;LEU A 102","None","0.92A","4xi3C-2w8sA:undetectable","4xi3C-2w8sA:17.84"],["4XK8_A_PQNA844_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"MET A 129;PHE A 132;ALA A  92;LEU A  93","None","1.08A","4xk8A-2w8sA:undetectable","4xk8A-2w8sA:21.47"],["5B1A_P_CHDP307_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.28A","5b1aN-2w8sA:undetectable;5b1aP-2w8sA:undetectable","5b1aN-2w8sA:19.33;5b1aP-2w8sA:17.78"],["5B1B_P_CHDP307_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.29A","5b1bN-2w8sA:undetectable;5b1bP-2w8sA:undetectable","5b1bN-2w8sA:19.33;5b1bP-2w8sA:17.78"],["5B3S_P_CHDP301_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.29A","5b3sN-2w8sA:undetectable;5b3sP-2w8sA:undetectable","5b3sN-2w8sA:19.33;5b3sP-2w8sA:17.78"],["5IY5_C_CHDC301_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.31A","5iy5A-2w8sA:undetectable;5iy5C-2w8sA:undetectable","5iy5A-2w8sA:19.33;5iy5C-2w8sA:17.94"],["5L8D_B_ACTB601_0","NICKEL-BINDING PERIPLASMIC PROTEIN","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",3,"THR A 277;PRO A 245;ASP A 246","None","0.83A","5l8dB-2w8sA:undetectable","5l8dB-2w8sA:23.20"],["5MWU_B_ACTB601_0","NICKEL-BINDING PERIPLASMIC PROTEIN","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",3,"THR A 277;PRO A 245;ASP A 246","None","0.83A","5mwuB-2w8sA:undetectable","5mwuB-2w8sA:23.20"],["5TIX_B_OQRB302_0","SULFOTRANSFERASE","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"ILE A 347;LEU A  22;VAL A 350;LEU A  45;GLU A 364","None","1.30A","5tixB-2w8sA:undetectable","5tixB-2w8sA:17.77"],["5U98_A_1KXA301_1","HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"TYR A 199;ILE A 103;VAL A 135;SER A 134;ILE A 128","None","1.46A","5u98A-2w8sA:3.4","5u98A-2w8sA:20.85"],["5U98_D_1KXD301_1","HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"TYR A 199;ILE A 103;VAL A 135;SER A 134;ILE A 128","None","1.47A","5u98D-2w8sA:2.4","5u98D-2w8sA:20.85"],["5V1T_A_SAMA605_0","RADICAL SAM","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"PHE A 209;LEU A  65;THR A 106;VAL A 135;TYR A 199","None","1.49A","5v1tA-2w8sA:undetectable","5v1tA-2w8sA:21.13"],["5VC0_A_RITA602_2","CYTOCHROME P450 3A4","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"ILE A 377;LEU A 349;PHE A  47;THR A  53","None","0.78A","5vc0A-2w8sA:undetectable","5vc0A-2w8sA:21.60"],["5X19_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.28A","5x19N-2w8sA:undetectable;5x19P-2w8sA:undetectable","5x19N-2w8sA:19.33;5x19P-2w8sA:17.78"],["5X1B_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.28A","5x1bN-2w8sA:undetectable;5x1bP-2w8sA:undetectable","5x1bN-2w8sA:19.33;5x1bP-2w8sA:17.78"],["5X1F_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"LEU A  87;MET A 374;THR A 376;LEU A 378","None","1.05A","5x1fA-2w8sA:undetectable;5x1fJ-2w8sA:undetectable","5x1fA-2w8sA:19.33;5x1fJ-2w8sA:8.11"],["5X1F_P_CHDP305_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.32A","5x1fN-2w8sA:undetectable;5x1fP-2w8sA:undetectable","5x1fN-2w8sA:19.33;5x1fP-2w8sA:17.78"],["5ZCQ_P_CHDP301_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.28A","5zcqN-2w8sA:undetectable;5zcqP-2w8sA:undetectable","5zcqN-2w8sA:19.33;5zcqP-2w8sA:17.78"],["6EW0_B_TA1B501_1","TUBULIN BETA CHAIN","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"VAL A 373;ASP A 372;LEU A  40;LEU A  37;LEU A 398","None","1.01A","6ew0B-2w8sA:undetectable","6ew0B-2w8sA:9.35"],["6EW0_D_TA1D501_1","TUBULIN BETA CHAIN","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"VAL A 373;ASP A 372;LEU A  40;LEU A  37;LEU A 398","None","1.01A","6ew0D-2w8sA:undetectable","6ew0D-2w8sA:9.35"],["6EW0_H_TA1H501_1","TUBULIN BETA CHAIN","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"VAL A 373;ASP A 372;LEU A  40;LEU A  37;LEU A 398","None","1.01A","6ew0H-2w8sA:undetectable","6ew0H-2w8sA:9.35"],["6EW0_I_TA1I501_1","TUBULIN BETA CHAIN","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"VAL A 373;ASP A 372;LEU A  40;LEU A  37;LEU A 398","None","1.01A","6ew0I-2w8sA:undetectable","6ew0I-2w8sA:9.35"],["6GNF_C_QPSC602_1","-","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"GLY A 336;TYR A 290;TRP A  14;HIS A 325;VAL A  55","None;None;None; ZN A1515 ( 3.2A);None","1.33A","6gnfC-2w8sA:undetectable","6gnfC-2w8sA:20.07"],["6GNG_A_QPSA601_2","-","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"GLY A 336;TYR A 290;TRP A  14;HIS A 325;VAL A  55","None;None;None; ZN A1515 ( 3.2A);None","1.37A","6gngA-2w8sA:undetectable","6gngA-2w8sA:22.31"],["6GNG_B_QPSB601_1","-","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",5,"TYR A 290;TRP A  14;HIS A 325;VAL A  55;GLY A 339","None;None; ZN A1515 ( 3.2A);None;None","1.47A","6gngB-2w8sA:undetectable","6gngB-2w8sA:22.31"],["6NKN_C_CHDC301_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.31A","6nknA-2w8sA:undetectable;6nknC-2w8sA:undetectable","6nknA-2w8sA:19.33;6nknC-2w8sA:17.78"],["6NMP_C_CHDC303_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.27A","6nmpA-2w8sA:undetectable;6nmpC-2w8sA:undetectable","6nmpA-2w8sA:19.33;6nmpC-2w8sA:17.78"],["6NMP_P_CHDP302_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 3","2w8s","PHOSPHONATE MONOESTER HYDROLASE","Paraburkholderia caryophylli",4,"HIS A 411;ASP A 482;TYR A 447;HIS A 494","None;None;None;SO4 A1517 (-4.1A)","1.31A","6nmpN-2w8sA:undetectable;6nmpP-2w8sA:undetectable","6nmpN-2w8sA:19.33;6nmpP-2w8sA:17.78"]]